Clinical trials in Almelo – page 3

61 clinical trials in Almelo, The Netherlands across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Almelo at a glance

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Paediatric trials0
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61 trials in Almelo

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Non-small cell lung cancer

Recruiting

Study of MK-1084 and Pembrolizumab for First-Line Treatment in Patients with Metastatic Non-Small Cell Lung Cancer with KRAS G12C Mutation and High PD-L1 Levels

Registered drug

Study of MK-1084 and Pembrolizumab for First-Line Treatment in Patients with Metastatic Non-Small Cell Lung Cancer with KRAS G12C Mutation and High PD-L1 Levels

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:MK-1084
Sponsor:Merck Sharp & Dohme LLC

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Prostate cancer

Recruiting

Study on Shortened Treatment with Apalutamide and Enzalutamide for Patients with Low-Volume Metastatic Castration-Sensitive Prostate Cancer

Registered drugNo placebo

Study on Shortened Treatment with Apalutamide and Enzalutamide for Patients with Low-Volume Metastatic Castration-Sensitive Prostate Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Apalutamide
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Rectal cancer

Recruiting

Study of drug combination (capecitabine, fluorouracil, oxaliplatin, calcium folinate) to prevent cancer recurrence in patients with detectable ctDNA after rectal cancer surgery

Registered drugNo placebo

Study of drug combination (capecitabine, fluorouracil, oxaliplatin, calcium folinate) to prevent cancer recurrence in patients with detectable ctDNA after rectal cancer surgery

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Calcium Folinate
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Hormone-refractory prostate cancer

Recruiting

Study on Docetaxel, Cabazitaxel, and Darolutamide for Men with Metastatic Castration-Resistant Prostate Cancer

Registered drugNo placebo

Study on Docetaxel, Cabazitaxel, and Darolutamide for Men with Metastatic Castration-Resistant Prostate Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Cabazitaxel
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Chronic lymphocytic leukaemia+1

Not yet recruiting

Study of Ibrutinib Plus Ritonavir in Adults with Chronic Lymphocytic Leukemia, Lymphoplasmacytic Lymphoma, and Mantle Cell Lymphoma

Registered drugNo placebo

Study of Ibrutinib Plus Ritonavir in Adults with Chronic Lymphocytic Leukemia, Lymphoplasmacytic Lymphoma, and Mantle Cell Lymphoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ibrutinib
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Chronic kidney disease

Not yet recruiting

A study to evaluate the effect of survodutide on protein levels in the urine for patients with chronic kidney disease

Investigational

A study to evaluate the effect of survodutide on protein levels in the urine for patients with chronic kidney disease

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:BI 456906
Sponsor:Universitair Medisch Centrum Groningen

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Thyroid mass+4

Not yet recruiting

Study Comparing Radiofrequency Ablation and Sodium Iodide (131I) for Treating Hyperthyroidism in Patients with Overactive Thyroid Nodules

Registered drugNo placebo

Study Comparing Radiofrequency Ablation and Sodium Iodide (131I) for Treating Hyperthyroidism in Patients with Overactive Thyroid Nodules

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Sodium iodide (131I)
Sponsor:Rijnstate Ziekenhuis Stichting

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Breast cancer

Not yet recruiting

Study Comparing Imlunestrant with Standard Endocrine Therapy for Patients with Early ER+, HER2- Breast Cancer at Increased Risk of Recurrence

Registered drugNo placebo

Study Comparing Imlunestrant with Standard Endocrine Therapy for Patients with Early ER+, HER2- Breast Cancer at Increased Risk of Recurrence

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Anastrozole
Sponsor:Eli Lilly & Co.

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Arteriosclerosis

Not recruiting

Study of maridebart cafraglutide to reduce cardiovascular problems in overweight or obese patients with atherosclerotic cardiovascular disease

Investigational

Study of maridebart cafraglutide to reduce cardiovascular problems in overweight or obese patients with atherosclerotic cardiovascular disease

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Maridebart Cafraglutide
Sponsor:Amgen Inc.

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Neuralgia

Not recruiting

Study on Capsaicin for Treating Post-Surgical Neuropathic Pain in Patients

Registered drugNo placebo

Study on Capsaicin for Treating Post-Surgical Neuropathic Pain in Patients

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capsaicin
Sponsor:Averitas Pharma Inc.

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Dyslipidaemia

Not recruiting

Study of Evolocumab to Prevent Heart Disease Events in High-Risk Patients Without Previous Heart Attack or Stroke

Registered drug

Study of Evolocumab to Prevent Heart Disease Events in High-Risk Patients Without Previous Heart Attack or Stroke

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Evolocumab
Sponsor:Amgen Inc.

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Atrial fibrillation

Not recruiting

Study on Milvexian and Apixaban for Preventing Stroke in Patients with Atrial Fibrillation

Registered drug

Study on Milvexian and Apixaban for Preventing Stroke in Patients with Atrial Fibrillation

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Andexanet Alfa
Sponsor:Janssen Cilag International

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Clinical research in Almelo

What the registry says about research in the country

01 Oncology Research

Innovative clinical trials focusing on advanced gastric cancer, prostate cancer, and breast cancer treatments. Studies include evaluation of new imaging techniques and therapeutic approaches for better disease management.

Gastric cancer staging and treatment
Prostate cancer diagnostics
HER2-positive breast cancer therapy

Research includes novel approaches to peritoneal dissemination and esophageal cancer treatment protocols.

02 Cardiovascular Studies

Comprehensive research into heart failure prevention and cardiovascular disease management, with emphasis on innovative drug combinations and preventive strategies.

Heart failure risk reduction
Atherosclerotic disease management
Post-surgical cardiac complications

Trials focus on both preventive measures and treatment optimization for various cardiac conditions.

03 Renal and Metabolic Disorders

Studies examining treatments for chronic kidney disease and type 2 diabetes, with particular focus on innovative therapeutic combinations and personalized treatment approaches.

Albuminuria management
Diabetic kidney disease
Treatment optimization strategies

Research emphasizes remote trial methodologies and personalized treatment protocols.

04 Hematology Research

Advanced studies in multiple myeloma and lymphoma treatments, exploring new therapeutic approaches and treatment-free intervals.

Multiple myeloma therapy
Non-Hodgkin lymphoma treatment
Targeted anti-cancer approaches

Focus on developing personalized treatment strategies and improving patient outcomes.

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