Clinical trials in Amsterdam – page 43

1 091 clinical trials in Amsterdam, The Netherlands across 13 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Amsterdam at a glance

1 091

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1 091 trials in Amsterdam

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Malignant melanoma stage IV+1

Not yet recruiting

A study of ipilimumab and nivolumab to observe immune system changes in patients with unresectable stage III or IV melanoma

Registered drugNo placebo

A study of ipilimumab and nivolumab to observe immune system changes in patients with unresectable stage III or IV melanoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ipilimumab
Sponsor:Amsterdam UMC Stichting

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Post-traumatic stress disorder

Not yet recruiting

A study to evaluate if hydrocortisone helps reduce symptoms of post-traumatic stress disorder in patients after exposure to a traumatic event.

Registered drug

A study to evaluate if hydrocortisone helps reduce symptoms of post-traumatic stress disorder in patients after exposure to a traumatic event.

Registered drug

The Netherlands

Participants:18–64 years · Healthy volunteers
Substances:Hydrocortisone
Sponsor:Amsterdam UMC Stichting

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Stomatitis

Not yet recruiting

Comparison of esketamine hydrochloride mouthwash and intravenous esketamine to reduce pain from oral mucositis in patients undergoing hematopoietic stem cell transplantation

Registered drugNo placebo

Comparison of esketamine hydrochloride mouthwash and intravenous esketamine to reduce pain from oral mucositis in patients undergoing hematopoietic stem cell transplantation

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Esketamine
Sponsor:Amsterdam UMC Stichting

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Idiopathic pulmonary fibrosis

Not yet recruiting

A study to evaluate the effectiveness and safety of admilparant in patients with idiopathic pulmonary fibrosis

Investigational

A study to evaluate the effectiveness and safety of admilparant in patients with idiopathic pulmonary fibrosis

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Admilparant
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Endometrial cancer+7

Not yet recruiting

A study to evaluate the safety of SGN-ALPV in patients with advanced solid tumors

InvestigationalNo placebo

A study to evaluate the safety of SGN-ALPV in patients with advanced solid tumors

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:SGN-ALPV
Sponsor:Seagen Inc.

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Glioblastoma

Not yet recruiting

Phase 3 Randomized Study of Niraparib Tosilate Monohydrate vs. Temozolomide in Newly Diagnosed MGMT Unmethylated Glioblastoma

Registered drugNo placebo

Phase 3 Randomized Study of Niraparib Tosilate Monohydrate vs. Temozolomide in Newly Diagnosed MGMT Unmethylated Glioblastoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Temozolomide
Sponsor:Neurotrials LLC

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Cerebral palsy

Not yet recruiting

Comparison of intrathecal baclofen pump and selective dorsal rhizotomy for children with cerebral palsy who cannot walk

Registered drugNo placebo

Comparison of intrathecal baclofen pump and selective dorsal rhizotomy for children with cerebral palsy who cannot walk

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Baclofen
Sponsor:UZ Leuven

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Type 1 diabetes mellitus+1

Not yet recruiting

A study testing dapagliflozin and SC0062 together compared to SC0062 alone in adults with type 1 diabetes and chronic kidney disease

Registered drugNo placebo

A study testing dapagliflozin and SC0062 together compared to SC0062 alone in adults with type 1 diabetes and chronic kidney disease

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Dapagliflozin
Sponsor:Universitair Medisch Centrum Groningen

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Hormone-dependent prostate cancer+1

Not yet recruiting

Study of Darolutamide to Increase PSMA Protein Expression in Patients with Hormone Sensitive Prostate Cancer

Registered drugNo placebo

Study of Darolutamide to Increase PSMA Protein Expression in Patients with Hormone Sensitive Prostate Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Darolutamide
Sponsor:Amsterdam UMC Stichting

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Lung neoplasm malignant

Not yet recruiting

Testing F-18-AraG imaging scan reliability in patients with lung cancer using repeat scans

Registered drugNo placebo

Testing F-18-AraG imaging scan reliability in patients with lung cancer using repeat scans

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Nelarabine
Sponsor:Amsterdam UMC Stichting

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Non-small cell lung cancer

Not yet recruiting

Study of Izalontamab Brengitecan versus Platinum-based Chemotherapy for Patients with EGFR-mutated Non-small Cell Lung Cancer after EGFR Inhibitor Treatment

Registered drugNo placebo

Study of Izalontamab Brengitecan versus Platinum-based Chemotherapy for Patients with EGFR-mutated Non-small Cell Lung Cancer after EGFR Inhibitor Treatment

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Cervix carcinoma

Not yet recruiting

A study of pembrolizumab and lenvatinib for patients with high risk locally advanced cervical cancer after chemoradiotherapy and brachytherapy

Registered drugNo placebo

A study of pembrolizumab and lenvatinib for patients with high risk locally advanced cervical cancer after chemoradiotherapy and brachytherapy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Lenvatinib
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Clinical research in Amsterdam

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01 Oncology Research

Innovative clinical trials focusing on colorectal cancer, bladder cancer, and gastric cancer treatments. Studies include novel combination therapies and immunological approaches to improve patient outcomes.

Advanced cancer treatments
Immunotherapy studies
Diagnostic imaging innovations

Research includes evaluation of new drug combinations and targeted therapies for various cancer types.

02 Neurological Studies

Groundbreaking research into Alzheimer's Disease and inflammatory polyneuropathy, focusing on early detection and treatment effectiveness. Studies include innovative biomarker research and twin-based investigations.

Preclinical Alzheimer's research
Neurological disorders
Biomarker studies

Emphasis on understanding disease progression and developing new therapeutic approaches.

03 Immunology and Infectious Diseases

Studies examining HPV prevention, mpox vaccination, and various immune-related conditions. Research includes vaccine effectiveness and novel treatment approaches for chronic conditions.

Vaccine studies
Viral infections
Immune system responses

Focus on preventive measures and treatment optimization for infectious diseases.

04 Specialized Therapeutics

Research involving eye conditions, dermatological treatments, and gastrointestinal disorders. Studies range from prosthetic eye care to innovative treatments for chronic conditions.

Ophthalmological care
Dermatology treatments
Digestive disorders

Investigating new therapeutic approaches for various specialized medical conditions.

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