Clinical trials in Amsterdam – page 5

1 091 clinical trials in Amsterdam, The Netherlands across 13 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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1 091

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1 091 trials in Amsterdam

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Gastrooesophageal cancer+6

Recruiting

Study of Rinatabart Sesutecan with glatiramer acetate in patients with advanced gastrointestinal cancers

Registered drugNo placebo

Study of Rinatabart Sesutecan with glatiramer acetate in patients with advanced gastrointestinal cancers

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Glatiramer Acetate
Sponsor:Genmab A/S

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Adenocarcinoma pancreas

Recruiting

First‑line Study of RMC‑9805 with Investigator’s Choice Chemotherapy Drug Combination vs Chemotherapy Alone in Patients with Metastatic KRAS G12D‑Mutated Pancreatic Adenocarcinoma

Investigational

First‑line Study of RMC‑9805 with Investigator’s Choice Chemotherapy Drug Combination vs Chemotherapy Alone in Patients with Metastatic KRAS G12D‑Mutated Pancreatic Adenocarcinoma

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:(2S)-2-CYCLOPENTYL-2-[(5S)-2-[(2R,3R)-3-CYCLOPROPYL-1-METHYLAZIRIDINE-2-CARBONYL]-2,7-DIAZASPIRO[4.4]NONAN-7-YL]-N-[(6S,8S,14S)-21-[5-(4-CYCLOPROPYLPIPERAZIN-1-YL)-2-[(1S)-1-METHOXYETHYL]PYRIDIN-3-YL]-18,18-DIMETHYL-9,15-DIOXO-22-(2,2,2-TRIFLUOROETHYL)-5,16-DIOXA-2,10,22,28-TETRAZAPENTACYCLO[18.5.2.12,6.110,14.023,27]NONACOSA-1(26),20,23(27),24-TETRAEN-8-YL]ACETAMIDE
Sponsor:Revolution Medicines Inc.

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Gastrointestinal stromal tumour

Recruiting

Phase 3 Study of GSK6042981 versus Imatinib in Adults with Previously Untreated Metastatic or Unresectable Gastrointestinal Stromal Tumors (GIST)

InvestigationalNo placebo

Phase 3 Study of GSK6042981 versus Imatinib in Adults with Previously Untreated Metastatic or Unresectable Gastrointestinal Stromal Tumors (GIST)

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Imatinib Mesilate
Sponsor:Glaxosmithkline Research & Development Limited

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Lipoprotein (a) increased

Recruiting

Phase 2 study of MK-7262 and enlicitide decanoate in adults with high lipoprotein(a)

Investigational

Phase 2 study of MK-7262 and enlicitide decanoate in adults with high lipoprotein(a)

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Merck Sharp & Dohme LLC

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Obesity+1

Recruiting

Efficacy and safety of oral semaglutide for weight loss in adults with overweight or obesity

Registered drug

Efficacy and safety of oral semaglutide for weight loss in adults with overweight or obesity

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Semaglutide
Sponsor:Novo Nordisk A/S

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Idiopathic pulmonary fibrosis

Recruiting

Phase IIb Study of AZD8965 versus Placebo in Adults with Idiopathic Pulmonary Fibrosis

Investigational

Phase IIb Study of AZD8965 versus Placebo in Adults with Idiopathic Pulmonary Fibrosis

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:AstraZeneca AB

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Colitis ulcerative

Recruiting

Efficacy and Safety of JNJ-78934804 (guselkumab and golimumab) in Adults with Moderately to Severely Active Ulcerative Colitis

InvestigationalNo placebo

Efficacy and Safety of JNJ-78934804 (guselkumab and golimumab) in Adults with Moderately to Severely Active Ulcerative Colitis

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Golimumab
Sponsor:Janssen Cilag International

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Infectious pleural effusion

Recruiting

Intrapleural Alteplase and Dornase Alfa versus VATS for Patients with Pleural Empyema (Parapneumonic Pleural Infection)

Registered drugNo placebo

Intrapleural Alteplase and Dornase Alfa versus VATS for Patients with Pleural Empyema (Parapneumonic Pleural Infection)

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Alteplase
Sponsor:Amsterdam UMC Stichting

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Dementia Alzheimer's type

Recruiting

Phase 2 Randomized Study of Mivelsiran in Adults with Early-Stage Down Syndrome-Associated Alzheimer’s Disease

Investigational

Phase 2 Randomized Study of Mivelsiran in Adults with Early-Stage Down Syndrome-Associated Alzheimer’s Disease

Investigational

The Netherlands

Participants:18–64 years
Substances:ALN-961583
Sponsor:Alnylam Pharmaceuticals Inc.

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Cholangitis sclerosing

Recruiting

A Phase III Study of Elafibranor in Adults with Primary Sclerosing Cholangitis to Assess Efficacy and Safety

Investigational

A Phase III Study of Elafibranor in Adults with Primary Sclerosing Cholangitis to Assess Efficacy and Safety

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Elafibranor
Sponsor:Ipsen Bioscience Inc.

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HIV infection

Recruiting

Switching to Lenacapavir, Teropavimab, and Zinlirvimab in Virologically Suppressed Adults with HIV-1: A Phase 3 Randomized Study

Registered drugNo placebo

Switching to Lenacapavir, Teropavimab, and Zinlirvimab in Virologically Suppressed Adults with HIV-1: A Phase 3 Randomized Study

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Abacavir
Sponsor:Gilead Sciences Inc.

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Prostate cancer

Recruiting

Phase 1/2 First‑in‑Human Study of Oral GSK5471713B in Adults with Metastatic Castration‑Resistant Prostate Cancer

InvestigationalNo placebo

Phase 1/2 First‑in‑Human Study of Oral GSK5471713B in Adults with Metastatic Castration‑Resistant Prostate Cancer

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Glaxosmithkline Research & Development Limited

Contact Research Centre

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Clinical research in Amsterdam

What the registry says about research in the country

01 Oncology Research

Innovative clinical trials focusing on colorectal cancer, bladder cancer, and gastric cancer treatments. Studies include novel combination therapies and immunological approaches to improve patient outcomes.

Advanced cancer treatments
Immunotherapy studies
Diagnostic imaging innovations

Research includes evaluation of new drug combinations and targeted therapies for various cancer types.

02 Neurological Studies

Groundbreaking research into Alzheimer's Disease and inflammatory polyneuropathy, focusing on early detection and treatment effectiveness. Studies include innovative biomarker research and twin-based investigations.

Preclinical Alzheimer's research
Neurological disorders
Biomarker studies

Emphasis on understanding disease progression and developing new therapeutic approaches.

03 Immunology and Infectious Diseases

Studies examining HPV prevention, mpox vaccination, and various immune-related conditions. Research includes vaccine effectiveness and novel treatment approaches for chronic conditions.

Vaccine studies
Viral infections
Immune system responses

Focus on preventive measures and treatment optimization for infectious diseases.

04 Specialized Therapeutics

Research involving eye conditions, dermatological treatments, and gastrointestinal disorders. Studies range from prosthetic eye care to innovative treatments for chronic conditions.

Ophthalmological care
Dermatology treatments
Digestive disorders

Investigating new therapeutic approaches for various specialized medical conditions.

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