Abemaciclib plus drug combination in women with early-stage hormone‑positive HER2‑negative breast cancer: phase II study to reduce chemotherapy and surgery

Registered drugNo placebo

Abemaciclib plus drug combination in women with early-stage hormone‑positive HER2‑negative breast cancer: phase II study to reduce chemotherapy and surgery

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Abemaciclib
Sponsor:Istituto Di Ricerche Farmacologiche Mario Negri

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Clinical research in Bergamo

What the registry says about research in the country

01 Cardiovascular Research

Innovative trials exploring treatments for heart failure prevention and cardiovascular disease. Studies include evaluation of novel drug combinations and therapies for patients with elevated cardiovascular risks.

Heart Failure Prevention
Myocardial Infarction Treatment
Cardiovascular Risk Management

02 Oncology Studies

Comprehensive research focusing on various cancer types, including non-small cell lung cancer and prostate cancer. Studies evaluate innovative treatment approaches combining immunotherapy with traditional methods.

Lung Cancer Therapies
Prostate Cancer Treatment
Breast Cancer Research

03 Rare Diseases

Specialized trials investigating treatments for conditions like Alagille syndrome and amyotrophic lateral sclerosis. Research focuses on improving patient outcomes and quality of life.

Genetic Disorders
Neurological Conditions
Rare Blood Disorders

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Clinical trials in Bergamo – page 14

388 trials in Bergamo

Malignant lymphoid neoplasm

Long-Term Follow-Up Study for Patients Treated with Idecabtagene Vicleucel or Lisocabtagene Maraleucel for Cancer

Study on the Effectiveness and Safety of Ademetionine with Antidepressants for Patients with Major Depressive Disorder

Study on the Effectiveness and Safety of Ademetionine with Antidepressants for Patients with Major Depressive Disorder

Antithrombin III deficiency

Study on the Effectiveness of Atenativ for Patients with Congenital Antithrombin Deficiency Undergoing Surgery or Childbirth

Inflammatory bowel disease

Study on the Effectiveness of Infliximab for Children with Inflammatory Bowel Disease

Alcoholic liver disease

Study on the Safety and Effectiveness of GSK4532990 for Adults Aged 18-65 with Alcohol-Related Liver Disease

Triple negative breast cancer

Study of Sacituzumab Govitecan and Pembrolizumab for Patients with Triple Negative Breast Cancer with Residual Disease After Surgery and Therapy

Atrial fibrillation

Prevention of Stroke and Systemic Embolism in Atrial Fibrillation Patients Treated with REGN7508 (cenvacibart) versus Apixaban

Ocular myasthenia

Phase 3 Open‑Label Extension Study of Long‑Term Safety and Efficacy of Rozanolixizumab in Adults with Ocular Myasthenia Gravis

Ocular myasthenia

A Phase 3 Randomized Study of Rozanolixizumab for Safety and Efficacy in Adults with Ocular Myasthenia Gravis

C3 glomerulopathy

Pegcetacoplan to Prevent Recurrence of C3 Glomerulopathy or Primary Immune‑Complex MPGN in Adolescent and Adult Kidney Transplant Recipients

Non-small cell lung cancer stage IV

Osimertinib and drug combination in metastatic non‑small cell lung cancer with targetable genomic driver alterations

Hormone receptor positive breast cancer+2

Abemaciclib plus drug combination in women with early-stage hormone‑positive HER2‑negative breast cancer: phase II study to reduce chemotherapy and surgery

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Clinical research in Bergamo

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