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Clinical trials in Bielefeld – page 5

146 clinical trials in Bielefeld, Germany across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Bielefeld at a glance
146
clinical trials
  • Research sites1
Type of trial
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146 trials in Bielefeld

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Herpes simplex+1

Recruiting

Study on the Effect of Acyclovir in ICU Patients with Pneumonia and Herpes Simplex Virus Type 1 Detected in Lung Fluid

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Aciclovir
  • Sponsor:Friedrich-Schiller-Universitaet Jena

Generalised tonic-clonic seizure+1

Recruiting

Study on the Long-term Safety and Tolerability of Azetukalner for Patients with Epilepsy, Including Focal-onset and Primary Generalized Tonic-Clonic Seizures

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Schizoaffective disorder+2

Recruiting

Study on the Effect of Clozapine and Drug Combination for Patients with Schizophrenia Experiencing First-Line Treatment Failure

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Amisulpride
  • Sponsor:Universitair Medisch Centrum Utrecht

Neurodevelopmental disorder

Recruiting

Study on the Safety and Effects of Radiprodil for Children with GRIN-related Disorder

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years
  • Substances:Radiprodil
  • Sponsor:Grin Therapeutics Inc.

Bipolar disorder

Recruiting

Study on the Effect of Citalopram, Sertraline, and Lithium for Patients with Bipolar Depression After First-Line Treatment Failure

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Citalopram
  • Sponsor:Universitair Medisch Centrum Utrecht

Major depression

Recruiting

Study on the Effect of Ketamine and Esketamine in Patients with Major Depressive Disorder After First-Line Treatment Failure

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Agomelatine
  • Sponsor:Universitair Medisch Centrum Utrecht

Nasopharyngeal cancer

Recruiting

Study of Nivolumab, Cisplatin, and 5-Fluorouracil for Children and Adults with EBV-Positive Nasopharyngeal Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years
  • Substances:Carboplatin
  • Sponsor:GPOH gGmbH

Anaplastic large cell lymphoma T- and null-cell types

Recruiting

Study on Vinblastine for Children and Adolescents with Standard Risk ALK-Positive Anaplastic Large Cell Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Vinblastine Sulfate
  • Sponsor:GPOH gGmbH

Ewing's sarcoma

Recruiting

Study on Ewing Sarcoma Treatment with Vinorelbine and Drug Combination for Patients with Primary and Disseminated Disease

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years
  • Substances:Cyclophosphamide
  • Sponsor:GPOH gGmbH

Partial seizures

Recruiting

Study on the Effects of Azetukalner in Patients with Focal-Onset Seizures

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Generalised tonic-clonic seizure

Recruiting

Study on the Effects of XEN1101 and Placebo for Patients with Primary Generalized Tonic-Clonic Seizures

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Azetukalner
  • Sponsor:Xenon Pharmaceuticals Inc.

Breast cancer

Recruiting

Study on the Effectiveness of Inavolisib with Trastuzumab and Pertuzumab for Patients with HER2-Positive, HR-Positive, PIK3CA Mutant Early Breast Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Inavolisib
  • Sponsor:GBG Forschungs GmbH

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Clinical research in Bielefeld

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01 Oncology Research

Extensive studies focusing on breast cancer treatments, including innovative therapies for HR-positive and HER2-negative variants. Research extends to gastric cancer and advanced ovarian cancer treatments.

  • Early-stage breast cancer therapies
  • Gastroesophageal junction cancer treatments
  • Ovarian cancer maintenance therapy

Novel combinations of targeted therapies and immunotherapies are being evaluated for improved patient outcomes.

02 Neurological Disorders

Comprehensive research into epilepsy and seizure disorders, with particular focus on both focal onset and generalized seizures. Studies include investigations of new treatments for Dravet Syndrome.

  • Seizure frequency reduction therapies
  • Extended-release anticonvulsant medications
  • Migraine prevention treatments

Emphasis on developing long-term treatment solutions for various seizure types.

03 Dermatology Studies

Investigation of treatments for plaque psoriasis and preventive measures for atopic dermatitis in high-risk populations. Focus on both adult and pediatric patients.

  • Moderate to severe psoriasis treatments
  • Preventive dermatological care
  • Long-term safety evaluations

Studies aim to develop effective management strategies for chronic skin conditions.

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