Clinical trials in Brezno

20 clinical trials in Brezno, Slovakia. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Brezno at a glance

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20 trials in Brezno

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Cardiovascular disorder+1

Recruiting

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational

Slovakia

Participants:18–64 years · 65+ years
Substances:Zilebesiran
Sponsor:Alnylam Pharmaceuticals Inc.

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Arteriosclerosis

Recruiting

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational

Slovakia

Participants:18–64 years · 65+ years
Substances:Laroprovstat
Sponsor:AstraZeneca AB

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Study on Baxdrostat and Dapagliflozin for Preventing Heart Failure in Patients at High Risk

Recruiting

Registered drug

Study on Baxdrostat and Dapagliflozin for Preventing Heart Failure in Patients at High Risk

Registered drug

Slovakia

Participants:18–64 years · 65+ years
Substances:Baxdrostat
Sponsor:AstraZeneca AB

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Chronic obstructive pulmonary disease

Recruiting

Study on the Effects of Budesonide, Glycopyrronium, and Formoterol Fumarate for Patients with Chronic Obstructive Pulmonary Disease (COPD)

Registered drugNo placebo

Study on the Effects of Budesonide, Glycopyrronium, and Formoterol Fumarate for Patients with Chronic Obstructive Pulmonary Disease (COPD)

Registered drugNo placebo

Slovakia

Participants:18–64 years · 65+ years
Substances:Budesonide
Sponsor:AstraZeneca AB

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Heart failure with preserved ejection fraction

Recruiting

Effect of elecoglipron plus dapagliflozin on cardiovascular outcomes in adults with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF)

Registered drug

Effect of elecoglipron plus dapagliflozin on cardiovascular outcomes in adults with heart failure with preserved or mildly reduced ejection fraction (HFpEF/HFmrEF)

Registered drug

Slovakia

Participants:18–64 years · 65+ years
Substances:AZD5004
Sponsor:AstraZeneca AB

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Cardiac failure

Recruiting

Evaluating the Effect of Vicadrostat and Empagliflozin Combination Compared to Empagliflozin Alone in Patients with Heart Failure and Reduced Left Ventricular Function

Registered drug

Evaluating the Effect of Vicadrostat and Empagliflozin Combination Compared to Empagliflozin Alone in Patients with Heart Failure and Reduced Left Ventricular Function

Registered drug

Slovakia

Participants:18–64 years · 65+ years
Substances:BI 690517
Sponsor:Boehringer Ingelheim International GmbH

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Cardiac failure

Recruiting

Study on Balcinrenone and Dapagliflozin for Patients with Heart Failure and Kidney Problems

Registered drug

Study on Balcinrenone and Dapagliflozin for Patients with Heart Failure and Kidney Problems

Registered drug

Slovakia

Participants:18–64 years · 65+ years
Substances:Balcinrenone
Sponsor:AstraZeneca AB

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Arteriosclerosis

Not recruiting

A study to evaluate the effect of olpasiran on major cardiovascular events in patients with atherosclerotic cardiovascular disease and high levels of lipoprotein(a)

Investigational

A study to evaluate the effect of olpasiran on major cardiovascular events in patients with atherosclerotic cardiovascular disease and high levels of lipoprotein(a)

Investigational

Slovakia

Participants:18–64 years · 65+ years
Sponsor:Amgen Inc.

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Cardiac failure

Not recruiting

A study comparing ziltivekimab to placebo in patients with heart failure with mildly reduced or preserved ejection fraction and inflammation

Investigational

A study comparing ziltivekimab to placebo in patients with heart failure with mildly reduced or preserved ejection fraction and inflammation

Investigational

Slovakia

Participants:18–64 years · 65+ years
Substances:Ziltivekimab
Sponsor:Novo Nordisk A/S

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Arteriosclerosis

Not recruiting

Study on the Effects of Pelacarsen on Heart Disease in Patients with Cardiovascular Conditions

Investigational

Study on the Effects of Pelacarsen on Heart Disease in Patients with Cardiovascular Conditions

Investigational

Slovakia

Participants:18–64 years · 65+ years
Substances:Pelacarsen
Sponsor:Novartis Pharma AG

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Dyslipidaemia

Not recruiting

Study of Evolocumab to Prevent Heart Disease Events in High-Risk Patients Without Previous Heart Attack or Stroke

Registered drug

Study of Evolocumab to Prevent Heart Disease Events in High-Risk Patients Without Previous Heart Attack or Stroke

Registered drug

Slovakia

Participants:18–64 years · 65+ years
Substances:Evolocumab
Sponsor:Amgen Inc.

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Familial hypertriglyceridaemia+1

Not recruiting

Study of Olezarsen (ISIS 678354) in Patients with Severe Hypertriglyceridemia: Testing Effects on Triglyceride Levels

Investigational

Study of Olezarsen (ISIS 678354) in Patients with Severe Hypertriglyceridemia: Testing Effects on Triglyceride Levels

Investigational

Slovakia

Participants:18–64 years · 65+ years
Substances:ISIS 678354 sodium salt
Sponsor:Ionis Pharmaceuticals Inc.

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Clinical research in Brezno

What the registry says about research in the country

01 Cardiovascular Research

Advanced clinical trials focusing on heart failure prevention and innovative treatments for cardiovascular disease. Studies are evaluating new therapeutic combinations and investigating treatments for atherosclerotic conditions.

Heart Failure Prevention
Atherosclerotic Disease Management
Cardiovascular Risk Reduction

Breakthrough research combining established treatments with novel compounds to enhance patient outcomes.

02 Blood Disorders & Stroke Prevention

Innovative trials examining new approaches to prevent stroke and manage atrial fibrillation. Research focuses on comparing novel anticoagulants with existing treatments.

Stroke Prevention Therapies
Atrial Fibrillation Management
Blood Clot Prevention

Studies aim to improve protection against stroke while enhancing safety profiles.

03 Metabolic & Lipid Disorders

Research targeting severe hypertriglyceridemia and dyslipidemia. Studies evaluate new compounds for managing blood lipid levels and associated cardiovascular risks.

Lipid Level Management
Triglyceride Reduction
Cholesterol Control

Trials focus on developing targeted therapies for complex metabolic conditions.

04 Respiratory Medicine

Clinical studies examining advanced treatments for Chronic Obstructive Pulmonary Disease. Research evaluates combination therapies for improved respiratory outcomes.

COPD Management
Respiratory Function
Cardiopulmonary Outcomes

Investigating innovative inhaler combinations for enhanced therapeutic benefits.

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