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Clinical trials in Dublin – page 6

445 clinical trials in Dublin, Ireland across 14 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Dublin at a glance
445
clinical trials
  • Research sites14
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445 trials in Dublin

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Study comparing GSK5764227 and topotecan in adults with relapsed small cell lung cancer

Registered drugNo placebo
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:GSK5764227
  • Sponsor:Glaxosmithkline Research & Development Limited

Colitis ulcerative+1

Recruiting

Long-term safety study of subcutaneous vedolizumab in children and adolescents with ulcerative colitis or Crohn's disease

Registered drugNo placebo
Countries:IrelandIreland
  • Participants:0–17 years
  • Substances:Vedolizumab
  • Sponsor:Takeda Development Center Americas Inc.

Cardiomyopathy

Recruiting

Study of Nucresiran in Adults with Transthyretin Amyloidosis with Cardiomyopathy to Evaluate its Effects on Survival and Heart Problems

Investigational
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Sponsor:Alnylam Pharmaceuticals Inc.

Study of cemiplimab treatment after surgery in patients with stage II-IIIA non-small cell lung cancer who have not received chemotherapy and have PD-L1 expression of 1% or higher

Registered drugNo placebo
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Cemiplimab
  • Sponsor:ETOP IBCSG Partners Foundation

Study comparing daratumumab, lenalidomide and dexamethasone followed by linvoseltamab versus continued initial treatment in newly diagnosed multiple myeloma patients

Registered drugNo placebo
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Daratumumab
  • Sponsor:Emn Trial Office S.r.l. Impresa Sociale

Study of ficerafusp alfa and pembrolizumab as first treatment for patients with PD-L1-positive recurrent or metastatic head and neck cancer

Registered drug
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Bicara Therapeutics Inc.

Study of deupsilocin besilate (CYB003) in adults with major depressive disorder comparing two doses against placebo

Investigational
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Deupsilocin besilate
  • Sponsor:Cybin IRL Limited

Study of MTX-463 compared to placebo to assess its safety and effectiveness in adults with idiopathic pulmonary fibrosis

Registered drug
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Glucose Monohydrate
  • Sponsor:Mediar Therapeutics Inc.

Study comparing RMC-6236 and docetaxel in previously treated patients with advanced or metastatic non-small cell lung cancer who have RAS mutations

Registered drugNo placebo
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:Revolution Medicines Inc.

Study of sonrotoclax plus obinutuzumab or rituximab compared to venetoclax plus rituximab in patients with relapsed or refractory chronic lymphocytic leukemia

Registered drugNo placebo
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Obinutuzumab
  • Sponsor:BeOne Medicines AG

Long-term safety and effectiveness study of CYB003 (deupsilocin besilate) with optional additional doses for people with Major Depressive Disorder

InvestigationalNo placebo
Countries:IrelandIreland
  • Participants:18–64 years · 65+ years
  • Substances:Deupsilocin besilate
  • Sponsor:Cybin IRL Limited

Phenylketonuria

Recruiting

Study of Long-Term Neurocognitive Outcomes in Children with Phenylketonuria Treated with Sepiapterin

Registered drugNo placebo
Countries:IrelandIreland
  • Participants:0–17 years
  • Substances:Sepiapterin
  • Sponsor:PTC Therapeutics Inc.

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Clinical research in Dublin

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01 Oncology Research

Clinical trials investigating innovative treatments for various cancer types, including non-small cell lung cancer, diffuse large B-cell lymphoma, and multiple myeloma. Studies focus on evaluating novel therapeutic combinations and immunotherapy approaches.

  • Metastatic Breast Cancer Treatment
  • Prostate Cancer Therapies
  • Lymphoma Management

Research emphasizes improving patient outcomes through targeted therapies and combination treatments.

02 Infectious Disease Prevention

Studies examining preventive measures against infectious diseases, including HIV prevention and monkeypox vaccination. Research focuses on vaccine efficacy and prophylactic treatments.

  • Pre-exposure Prophylaxis
  • Vaccine Booster Studies
  • Immunogenicity Assessment

Trials aim to enhance protection against emerging infectious diseases through innovative approaches.

03 Chronic Disease Management

Investigations into treatments for chronic conditions, including Sjögren's Disease, Ulcerative Colitis, and Hereditary Angioedema. Studies evaluate both novel therapeutics and existing treatment optimization.

  • Autoimmune Disorders
  • Inflammatory Conditions
  • Metabolic Diseases

Research focuses on improving quality of life and disease management for patients with chronic conditions.

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