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Clinical trials in Frankfurt (oder)

7 clinical trials in Frankfurt (oder), Germany. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Frankfurt (oder) at a glance
7
clinical trials
  • Not yet recruiting0
  • Paediatric trials0
  • Research sites0
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7 trials in Frankfurt (oder)

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Study on Acalabrutinib with Rituximab and Drug Combination for Older Adults with Untreated Diffuse Large B-Cell Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Acalabrutinib
  • Sponsor:Universitaet Des Saarlandes

Plasma cell myeloma

Not recruiting

Study on Adding Isatuximab to Lenalidomide, Bortezomib, and Dexamethasone for Patients with Newly Diagnosed Multiple Myeloma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bortezomib
  • Sponsor:Universitaetsklinikum Heidelberg AöR

Study of RO7269162 in people at risk for or with early-stage Alzheimer's Disease: Effects on brain amyloid buildup

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Florbetaben (18F)
  • Sponsor:F. Hoffmann-La Roche AG

Study on the Effectiveness and Safety of Odronextamab Compared to Standard Treatment in Adults with Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Regeneron Pharmaceuticals Inc.

Follicular lymphoma+2

Not recruiting

Study Comparing Odronextamab and Lenalidomide with Rituximab and Lenalidomide for Patients with Relapsed/Refractory Follicular and Marginal Zone Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Lenalidomide
  • Sponsor:Regeneron Pharmaceuticals Inc.

Study Comparing Obinutuzumab and Venetoclax with Obinutuzumab and Chlorambucil for Untreated Chronic Lymphocytic Leukemia Patients with Other Health Conditions

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Chlorambucil
  • Sponsor:F. Hoffmann-La Roche AG

Acute myeloid leukaemia+1

Not recruiting

Study Comparing CPX-351 and Conventional Drug Combination for Patients with High-Risk Myelodysplastic Syndromes and Oligoblastic Acute Myeloid Leukemia Before Stem Cell Transplant

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:GWT-Tud GmbH

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Clinical research in Frankfurt (oder)

What the registry says about research in the country

01 Hemic and Lymphatic Diseases

Clinical research in Frankfurt (oder) is strongly focused on blood cancers, with studies covering follicular lymphoma, marginal zone lymphoma, chronic lymphocytic leukemia, and multiple myeloma. These trials are mainly testing new treatment combinations and comparing them with current standard care to improve response and disease control.

  • New approaches for follicular lymphoma and related indolent lymphomas
  • Treatment studies in relapsed or refractory lymphoma and B-cell non-Hodgkin’s lymphoma
  • Therapy comparisons for chronic lymphocytic leukemia in patients with other health conditions
  • Trials in multiple myeloma and other hematologic cancers

The overall goal is to find safer and more effective options for patients with complex hematologic malignancies, especially where long-term disease control is a priority.

02 Neoplasms

Another major area of trial activity is cancer research in broader tumor types, including diffuse large B-cell lymphoma and other aggressive lymphomas. These studies are evaluating whether newer targeted or combined therapies can improve outcomes for older adults and people who may not tolerate intensive treatment well.

  • Studies for diffuse large B-cell lymphoma and other aggressive B-cell lymphomas
  • Research in older or less fit patients needing gentler treatment options
  • Comparisons of new immunotherapy-based regimens with standard chemotherapy
  • Trials designed to improve remission rates and disease-free survival

This reflects a practical effort to refine treatment choices in oncology, with attention to both effectiveness and tolerability.

03 Nervous System Diseases

Clinical trials in nervous system disease are centered on Alzheimer’s disease, exploring whether an investigational therapy can be safe and well tolerated while also influencing disease-related brain changes. The research aims to support earlier intervention and improve understanding of how treatment may affect the course of memory and cognitive decline.

  • Studies in Alzheimer’s disease at risk and early symptom stages
  • Research on safety and tolerability of a potential new therapy
  • Evaluation of effects on brain amyloid accumulation
  • Work aimed at better treatment strategies for neurodegenerative disease

These trials contribute to efforts in neurology to slow progression and improve future care for people affected by cognitive disorders.

04 Mixed Hematologic and Oncology Research

Several studies in the city also bridge multiple areas of hematology and oncology, including treatment strategies for patients preparing for allogeneic stem cell transplantation. These trials are looking at whether alternative regimens can better control disease before transplant and improve outcomes afterward.

  • Research in higher-risk MDS and oligoblastic AML
  • Treatment planning before allogeneic blood cell transplantation
  • Studies comparing disease control strategies ahead of transplant
  • Focus on improving progression-free and event-free survival

The research supports more tailored treatment pathways for patients with challenging blood disorders and advanced cancer-related conditions.

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