Clinical trials in Freiburg Im Breisgau – page 27

Neoplasms research in Freiburg covers a broad mix of cancer studies, from lung and colorectal cancer to breast, endometrial, prostate, sarcoma, and childhood leukemia. These trials are mainly focused on testing new treatments, improving cancer control, and refining treatment combinations for better outcomes.

• Advanced and metastatic solid tumors
• ALK+ NSCLC and small cell lung cancer
• HER2+ early breast cancer and HER2-expressing endometrial cancer
• Metastatic colorectal cancer, prostate cancer, sarcoma, and pediatric leukemia

Several studies are evaluating whether new cancer therapies can improve survival, delay recurrence, or support earlier and more effective treatment choices.

Clinical trials in nervous system diseases are examining acute stroke care and childhood cerebrovascular disorders. The research aims to improve recovery after stroke, reduce recurrence, and assess new treatment options for difficult cases.

• Acute ischemic stroke with incomplete reperfusion
• Stroke in children with focal cerebral arteriopathy
• Patients using direct oral anticoagulants who experience stroke

This area includes studies of thrombolysis and anti-inflammatory treatment strategies designed to improve functional outcomes and neurological recovery.

Freiburg also hosts studies in respiratory tract diseases and neonatal lung care, with a strong focus on preterm infants and oxygen-related support. These trials are evaluating ways to improve breathing outcomes and reduce complications in vulnerable newborns.

• Respiratory distress syndrome in preterm infants
• Extremely premature infants needing respiratory support
• Small cell lung cancer treatment combinations

In addition to newborn care, lung cancer research is testing whether newer oncology approaches can improve disease control in advanced respiratory malignancies.

A major part of the research landscape in Freiburg is dedicated to congenital, hereditary, and neonatal diseases. These studies focus on safer care for preterm infants, childhood stroke, and pediatric leukemia, with the goal of improving long-term health and survival.

• Preterm infants with very low gestational age
• Childhood leukemia
• Focal cerebral arteriopathy in children
• Long-term respiratory and neurological outcomes

The trials are designed to support better early treatment decisions and to reduce complications that can affect development later in life.

Studies in cardiovascular diseases and chronic kidney disease are exploring ways to slow disease progression and lower the risk of major heart-related events. The goal is to strengthen preventive care for people with long-term metabolic and organ-related conditions.

• Familial hypercholesterolemia
• Chronic kidney disease
• Heart and kidney protection strategies

These trials are looking at whether new treatment combinations can improve long-term safety and reduce complications in high-risk patients.

Trials in hormonal diseases and related metabolic conditions are addressing disorders that affect both quality of life and long-term health. This includes research on hormone-sensitive cancers, lipid disorders, and treatment approaches linked to kidney and heart protection.

• Metastatic hormone sensitive prostate cancer
• Familial hypercholesterolemia
• Metabolic support for patients with kidney disease

The studies aim to improve disease control and better tailor treatment to patients with chronic hormonal or metabolic risk factors.

Research in psychological phenomena includes clinical trials for ADHD in adults. These studies are focused on comparing treatment options that may help improve attention, daily functioning, and symptom control.

• Adult patients with ADHD
• Comparing stimulant treatment options with placebo

This area reflects an interest in evidence-based approaches for managing neurodevelopmental symptoms in adult care.

Freiburg’s clinical trials also include skin and connective tissue diseases, especially hair loss conditions. The research is evaluating new ways to improve hair growth and address androgen-related hair loss in both men and women.

• Androgenetic alopecia in men
• Female androgenetic alopecia
• Testing topical and oral treatment approaches

These studies are aimed at finding more effective and better-tolerated options for common hair disorders.

The city’s research portfolio includes otorhinolaryngologic diseases, with trials focused on sudden hearing loss. The main purpose is to assess whether new treatment options can improve hearing recovery more effectively than current care.

• Idiopathic sudden sensorineural hearing loss
• Comparing a novel ear treatment with standard steroid therapy

This work is especially relevant for rapid intervention in conditions where early treatment may influence long-term hearing outcomes.

Trials in digestive system diseases include research on bowel and rectal complications related to cancer treatment. These studies aim to reduce symptoms and improve comfort for patients undergoing oncologic care.

• Acute radiation proctitis
• Symptoms in men treated for prostate cancer
• Supportive care during cancer therapy

The focus is on symptom relief and improving quality of life during or after radiotherapy.

Research in male urogenital diseases includes prostate cancer studies and work on hair and hormonal conditions affecting men. The trials are testing whether new treatment strategies can improve disease control and patient well-being.

• Metastatic prostate cancer
• Prostate cancer with treatment-related rectal symptoms

In Freiburg, this area combines cancer research with supportive care questions that matter for everyday treatment experience.

A smaller set of studies addresses reproductive and urinary physiological phenomena, especially kidney-related health and treatment effects that influence urinary function. These trials are aimed at better protection of organ function over time.

• Chronic kidney disease
• Heart-kidney protection in patients with renal risk

The research reflects growing interest in preserving both cardiovascular and urinary system health in chronic disease.

Several Freiburg trials explore inflammatory mechanisms across different diseases, from stroke-related vessel disease to cancer and radiation injury. The main purpose is to see whether targeted anti-inflammatory or immune-based approaches can improve outcomes.

• Focal cerebral arteriopathy
• Acute radiation proctitis
• Immune-based cancer vaccination strategies

This field links inflammation research with practical treatment questions in both neurology and oncology.