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Clinical trials in Guarda

16 clinical trials in Guarda, Portugal across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Guarda at a glance
16
clinical trials
  • Paediatric trials0
  • Research sites1
Type of trial
Recruitment status
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16 trials in Guarda

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Study of Tucatinib, Trastuzumab, and mFOLFOX6 for Patients with HER2+ Metastatic Colorectal Cancer

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Seagen Inc.

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Depemokimab
  • Sponsor:Glaxosmithkline Research & Development Limited

Study on Long-Term Safety of Cenerimod for Adults with Moderate-to-Severe Systemic Lupus Erythematosus

InvestigationalNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Cenerimod
  • Sponsor:Viatris Innovation GmbH

Study on VE303 for Preventing Recurrent C. difficile Infection in Patients

Investigational
Countries:PortugalPortugal
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Bacilli, Cluster Xvii, Strain Relative Clostridium_Aq Innocuum, Live
  • Sponsor:Vedanta Biosciences Inc.

Type 2 diabetes mellitus

Not yet recruiting

Efficacy and Safety of Alogliptin Plus Empagliflozin Compared with Alogliptin Alone or Empagliflozin Alone in Adults with Type 2 Diabetes on Metformin

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Alogliptin
  • Sponsor:Tecnimede-Sociedade Tecnico-Medicinal S.A.

Cardiac failure

Not recruiting

A study comparing ziltivekimab to placebo in patients with heart failure with mildly reduced or preserved ejection fraction and inflammation

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Ziltivekimab
  • Sponsor:Novo Nordisk A/S

Psoriatic arthropathy

Not recruiting

Study on Guselkumab for Treating Psoriatic Arthritis in Patients New to Biologic Therapy

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Guselkumab
  • Sponsor:Janssen Cilag International

Study on the Effects of Semaglutide in Patients with Non-Alcoholic Steatohepatitis (NASH) and Fibrosis Stages 2 or 3

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Semaglutide
  • Sponsor:Novo Nordisk A/S

Giant cell arteritis

Not recruiting

Study on the Safety and Effectiveness of Upadacitinib and Prednisolone in Patients with Giant Cell Arteritis

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Prednisolone
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Study on Itepekimab for Former Smokers with Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Itepekimab
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Study on Preventing Infections After Abdominal Surgery Using D-PLEX with Doxycycline Hyclate for Patients Undergoing Abdominal Surgery

InvestigationalNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Doxycycline Hyclate
  • Sponsor:Polypid Ltd.

Rheumatoid arthritis

Not recruiting

Study on the Effects of Folate-Based Liposomes with Methotrexate for Patients with Moderate-to-Severe Rheumatoid Arthritis

InvestigationalNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Methotrexate
  • Sponsor:Solfarcos Solucoes Farmaceuticas E Cosmeticas Lda.

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Clinical research in Guarda

What the registry says about research in the country

01 Autoimmune Conditions

Clinical research focusing on innovative treatments for Sjögren's Syndrome and Systemic Lupus Erythematosus, evaluating new therapeutic approaches to manage these chronic conditions.

  • Sjögren's Syndrome Management
  • Lupus Treatment Innovations
  • Autoimmune Disease Therapy

Studies aim to improve quality of life and reduce disease activity in patients with autoimmune disorders.

02 Respiratory Medicine

Breakthrough research in treating severe asthma and COPD, with trials evaluating novel biologics and targeted therapies for patients with specific disease phenotypes.

  • Eosinophilic Asthma Treatment
  • COPD Management
  • Respiratory Disease Control

Focus on developing long-acting treatments to improve respiratory function and reduce exacerbations.

03 Oncology & Gastroenterology

Advanced studies in metastatic colorectal cancer treatment and research on non-alcoholic steatohepatitis, exploring targeted therapies and innovative treatment approaches.

  • HER2+ Colorectal Cancer Therapy
  • NASH Treatment Development
  • Liver Disease Management

Trials aim to improve survival rates and develop effective treatments for complex digestive system conditions.

04 Rheumatology

Innovative research on Rheumatoid Arthritis, Psoriatic Arthritis, and Giant Cell Arteritis, testing new therapeutic options and treatment combinations.

  • Advanced RA Treatments
  • Psoriatic Disease Management
  • Arteritis Therapy

Studies focus on improving disease control and reducing inflammation in rheumatic conditions.

05 Infection Prevention

Clinical studies addressing surgical site infections and Clostridioides difficile prevention, developing new approaches to combat healthcare-associated infections.

  • Post-Surgical Infection Prevention
  • C. difficile Treatment
  • Antimicrobial Strategies

Research aims to reduce infection rates and improve patient outcomes following medical procedures.

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