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Clinical trials in Halle (Saale) – page 4

337 clinical trials in Halle (Saale), Germany across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Halle (Saale) at a glance
337
clinical trials
  • Research sites2
Type of trial
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337 trials in Halle (Saale)

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A study of PF-08634404 and a drug combination in adults with advanced or metastatic non-small cell lung cancer

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Pfizer Inc.

Bronchiectasis

Recruiting

A study to evaluate the safety and effectiveness of AZD0292 in people aged 12 years and older with bronchiectasis and chronic Pseudomonas aeruginosa infection

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:AZD0292
  • Sponsor:AstraZeneca AB

A study to evaluate the effectiveness and safety of REGN13335 in adults with pulmonary arterial hypertension

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:HUMAN IGG4 KAPPA MONOCLONAL ANTIBODY AGAINST PLATELET-DERIVED GROWTH FACTOR SUBUNIT B
  • Sponsor:Regeneron Pharmaceuticals Inc.

A study of the humanised IgG1 lalaps-yte monoclonal antibody against lysophosphatidic acid receptor 1 to treat adults with idiopathic pulmonary fibrosis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:HUMANISED IGG1 LALAPS-YTE MONOCLONAL ANTIBODY AGAINST LYSOPHOSPHATIDIC ACID RECEPTOR 1
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

A study to evaluate the effectiveness and safety of remibrutinib in patients with secondary progressive multiple sclerosis

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Remibrutinib
  • Sponsor:Novartis Pharma AG

Study of ziftomenib with drug combinations for adults with newly diagnosed acute myeloid leukemia with NPM1 or KMT2A genetic changes

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Kura Oncology Inc.

A Study of S-606001 Added to Enzyme Replacement Therapy for Patients with Late-Onset Pompe Disease

Investigational
Countries:GermanyGermany
  • Participants:18–64 years
  • Sponsor:Shionogi B.V.

A study of bleximenib combined with intensive chemotherapy for adults with newly diagnosed acute myeloid leukemia with specific genetic changes.

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bleximenib
  • Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

Testing MK-2870 with pembrolizumab compared to pembrolizumab alone after surgery in patients with non-small cell lung cancer who did not respond fully to treatment

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Merck Sharp & Dohme LLC

A study of onfekafusp alfa and bifikafusp alfa injected into tumors for patients with advanced skin squamous cell cancer who did not respond to or could not tolerate previous treatment

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bifikafusp Alfa
  • Sponsor:Philogen S.p.A.

Study of bifikafusp alfa and onfekafusp alfa injected into tumors for patients with locally advanced basal cell carcinoma who progressed on or cannot tolerate systemic treatment

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bifikafusp Alfa
  • Sponsor:Philogen S.p.A.

Testing bifikafusp alfa and onfekafusp alfa injections in patients with locally advanced basal cell carcinoma

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bifikafusp Alfa
  • Sponsor:Philogen S.p.A.

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Clinical research in Halle (Saale)

What the registry says about research in the country

01 Oncology and Hematologic Malignancies

Clinical research in Halle (Saale) is strongly focused on cancer and blood disorders, with studies exploring new treatment options for solid tumors and leukemia, lymphoma, and related conditions.

  • Neoplasms and hematologic malignancies
  • Acute myeloid leukemia, lymphoma, and multiple myeloma
  • Testing newer combinations and more effective treatment strategies
  • Evaluating outcomes in advanced, relapsed, or high-risk disease

Many studies in this area aim to improve survival, disease control, and treatment options for patients with limited standard choices.

02 Lung and Respiratory Diseases

Another major research area covers respiratory tract diseases, especially non-small cell lung cancer, small cell lung cancer, and chronic lung conditions such as COPD and pulmonary fibrosis.

  • Non-small cell lung cancer and small cell lung cancer
  • Chronic obstructive pulmonary disease, bronchiectasis, and idiopathic pulmonary fibrosis
  • Assessing new therapies and maintenance approaches
  • Improving symptom control and long-term respiratory outcomes

The studies often focus on better disease management for both advanced cancers and chronic inflammatory lung disease.

03 Gastroenterology and Inflammatory Bowel Disease

Trials in digestive system diseases and immune-related disorders include important work on Crohn’s disease, ulcerative colitis, and other inflammatory conditions of the gut.

  • Crohn’s disease and ulcerative colitis
  • Coeliac disease and gastrointestinal inflammation
  • Studying new immune-targeted treatments
  • Improving control of active disease and remission rates

These projects aim to reduce symptoms, support remission, and improve quality of life for people with chronic intestinal disease.

04 Cardiovascular and Stroke Research

Cardiovascular diseases are represented by studies on heart failure, atrial fibrillation, stroke, and related complications after surgery or acute vascular events.

  • Heart failure and atrial fibrillation
  • Acute ischemic stroke and vascular occlusion
  • Testing ways to prevent complications and improve recovery
  • Evaluating safer and more effective cardiovascular care

Research in this field is aimed at lowering risk, improving emergency treatment, and supporting long-term heart and brain health.

05 Autoimmune and Immune-Mediated Disorders

Halle’s trial portfolio includes a broad set of studies on immune system diseases, including rheumatologic, skin-related, and other inflammatory conditions.

  • Lupus erythematosus, hidradenitis suppurativa, and giant cell arteritis
  • Atopic dermatitis and chronic spontaneous urticaria
  • Exploring immune-modulating therapies
  • Looking to reduce inflammation and improve daily functioning

These studies reflect a strong interest in better control of chronic immune-driven disease.

06 Hematology, Bone Marrow Transplantation, and Blood Clotting Disorders

A significant share of research addresses myeloid disorders, myeloproliferative neoplasms, and complications linked to stem cell transplantation.

  • Myelodysplastic syndromes, myelofibrosis, and essential thrombocythemia
  • Graft-versus-host disease and transplant-related complications
  • Evaluating better blood cancer and transplant treatments
  • Improving safety and disease control in high-risk patients

Much of this work focuses on patients with difficult-to-treat disease and the need for more precise supportive care.

07 Pediatric Oncology and Rare Childhood Diseases

The city also supports research into children’s cancers and other rare pediatric conditions, including tumors of the brain, blood, and soft tissue.

  • Medulloblastoma, neuroblastoma, and rhabdomyosarcoma
  • Acute lymphoblastic leukemia in children and adolescents
  • Testing more effective and less burdensome treatment approaches
  • Seeking better survival and long-term outcomes for young patients

These trials often aim to refine treatment so that cure rates improve while limiting lasting harm.

08 Neurology and Nervous System Conditions

Research also includes nervous system diseases such as stroke, multiple sclerosis, spinal cord injury, and certain rare neurological disorders.

  • Secondary progressive multiple sclerosis
  • Acute spinal cord injury and idiopathic sudden hearing loss
  • Evaluating therapies that may improve recovery or slow progression
  • Exploring care options for serious and uncommon neurological conditions

These studies are aimed at improving function, symptom relief, and neurological outcomes over time.

09 Metabolic, Kidney, and Endocrine Conditions

Trials in nutritional and metabolic diseases and kidney-related disorders focus on conditions that affect energy balance, organ function, and long-term health.

  • Obesity, metabolic disease, and mitochondrial disease
  • Chronic kidney disease and kidney-related complications
  • Studying ways to slow disease progression
  • Assessing treatments that may improve overall organ health

This area reflects interest in both common chronic illness and rarer inherited disorders.

10 Eye, Ear, and Other Diagnostic Research

Several studies address eye diseases, ear and nose conditions, and broader diagnostic techniques, showing a strong interest in improving how disease is detected and managed.

  • Diabetic macular edema and other vision-threatening eye conditions
  • Hearing loss and otologic disorders
  • Improving diagnosis and monitoring
  • Testing therapies that may preserve vision or sensory function

These projects highlight the role of better diagnostics alongside treatment development in everyday clinical care.

11 Infectious Diseases, Surgery, and Public Health

There is also work on bacterial infections, viral diseases, surgical complications, and public health questions, including prevention and perioperative care.

  • Viral and bacterial infections
  • Surgical bleeding, infection prevention, and post-operative complications
  • Evaluating supportive treatments and preventive strategies
  • Improving safety in hospital and surgical settings

These trials focus on practical clinical needs, from infection control to safer recovery after procedures.

12 Psychiatry and Behavioral Health

Some research in Halle addresses mental disorders and behavioral disciplines, reflecting interest in both emotional health and broader patient well-being.

  • Attention deficit hyperactivity disorder and borderline personality disorder
  • Studying approaches that may improve symptoms and functioning
  • Supporting better understanding of complex behavioral conditions
  • Exploring patient-centered care in mental health

These studies contribute to broader clinical research beyond traditional somatic disease areas.

13 Women’s Health, Fertility, and Urogenital Disorders

Trials also include female and male urogenital diseases, pregnancy-related issues, and fertility-related concerns, showing a balanced interest in reproductive health.

  • Pregnancy complications and vaginal infections
  • Infertility and urogenital disorders
  • Testing therapies for symptom relief and prevention
  • Improving health outcomes for women and men

These studies often aim to make everyday gynecologic and reproductive care more effective.

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