Clinical trials in Hoofddorp – page 3

77 clinical trials in Hoofddorp, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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77 trials in Hoofddorp

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Colorectal cancer metastatic

Recruiting

Dose-Reduced Oxaliplatin and Drug Combination Study for Older Patients with Metastatic Colorectal Cancer

Registered drugNo placebo

Dose-Reduced Oxaliplatin and Drug Combination Study for Older Patients with Metastatic Colorectal Cancer

Registered drugNo placebo

The Netherlands

Participants:65+ years
Substances:Capecitabine
Sponsor:Leiden University Medical Center

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Myelofibrosis+1

Recruiting

Study on the Effectiveness and Safety of Selinexor for Patients with Myelofibrosis and Moderate Thrombocytopenia Who Have Not Used JAK Inhibitors

Registered drugNo placebo

Study on the Effectiveness and Safety of Selinexor for Patients with Myelofibrosis and Moderate Thrombocytopenia Who Have Not Used JAK Inhibitors

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Aprepitant
Sponsor:Karyopharm Therapeutics Inc.

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Study Comparing Clindamycin to Rifampicin and Drug Combination for Patients with Prosthetic Joint Infection

Recruiting

Registered drugNo placebo

Study Comparing Clindamycin to Rifampicin and Drug Combination for Patients with Prosthetic Joint Infection

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Clindamycin
Sponsor:Leiden University Medical Center

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Study of Camizestrant for Patients with ER+/HER2- Early Breast Cancer After 2 Years of Standard Endocrine Therapy

Recruiting

Registered drugNo placebo

Study of Camizestrant for Patients with ER+/HER2- Early Breast Cancer After 2 Years of Standard Endocrine Therapy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Anastrozole
Sponsor:AstraZeneca AB

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Neoplasm malignant

Recruiting

Study on Preventing Opioid-Induced Constipation in Advanced Cancer Patients Using Magnesium Hydroxide and Macrogol 3350 Combination

Registered drugNo placebo

Study on Preventing Opioid-Induced Constipation in Advanced Cancer Patients Using Magnesium Hydroxide and Macrogol 3350 Combination

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Macrogol 3350
Sponsor:Amsterdam UMC Stichting

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Chronic lymphocytic leukaemia+1

Not yet recruiting

Study of Ibrutinib Plus Ritonavir in Adults with Chronic Lymphocytic Leukemia, Lymphoplasmacytic Lymphoma, and Mantle Cell Lymphoma

Registered drugNo placebo

Study of Ibrutinib Plus Ritonavir in Adults with Chronic Lymphocytic Leukemia, Lymphoplasmacytic Lymphoma, and Mantle Cell Lymphoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ibrutinib
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Diffuse large B-cell lymphoma

Not yet recruiting

Epcoritamab plus rituximab versus rituximab alone in elderly, frail or unfit patients with newly diagnosed diffuse large B‑cell lymphoma

Registered drugNo placebo

Epcoritamab plus rituximab versus rituximab alone in elderly, frail or unfit patients with newly diagnosed diffuse large B‑cell lymphoma

Registered drugNo placebo

The Netherlands

Participants:65+ years
Substances:Epcoritamab
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Hepatic cirrhosis

Not yet recruiting

Low‑dose human serum albumin versus standard dose during large‑volume paracentesis in patients with liver cirrhosis

Registered drugNo placebo

Low‑dose human serum albumin versus standard dose during large‑volume paracentesis in patients with liver cirrhosis

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Human Serum Albumin
Sponsor:Amsterdam UMC Stichting

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Cholelithiasis+2

Not yet recruiting

A study to evaluate if atorvastatin prevents gallstones in patients undergoing bariatric surgery

Registered drugNo placebo

A study to evaluate if atorvastatin prevents gallstones in patients undergoing bariatric surgery

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Atorvastatin
Sponsor:Spaarne Gasthuis Stichting

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Plasma cell myeloma refractory

Not yet recruiting

A Study of Linvoseltamab Alone and Linvoseltamab with Carfilzomib Compared to Standard Treatment in Adults with Relapsed or Refractory Multiple Myeloma

Registered drugNo placebo

A Study of Linvoseltamab Alone and Linvoseltamab with Carfilzomib Compared to Standard Treatment in Adults with Relapsed or Refractory Multiple Myeloma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Aciclovir
Sponsor:Regeneron Pharmaceuticals Inc.

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Bronchiectasis

Not yet recruiting

Study of Nebulized Human Normal Immunoglobulin (CSL787) for Adults with Non-cystic Fibrosis Bronchiectasis to Find Best Dose and Test Safety

Investigational

Study of Nebulized Human Normal Immunoglobulin (CSL787) for Adults with Non-cystic Fibrosis Bronchiectasis to Find Best Dose and Test Safety

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Human Normal Immunoglobulin
Sponsor:CSL Behring LLC

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Bladder transitional cell carcinoma+1

Not yet recruiting

Study on Avelumab for Patients with Advanced Urothelial Cancer After Initial Chemotherapy

Registered drugNo placebo

Study on Avelumab for Patients with Advanced Urothelial Cancer After Initial Chemotherapy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Avelumab
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Clinical research in Hoofddorp

What the registry says about research in the country

01 Oncology Research

Extensive research focusing on various cancer types including breast cancer, bladder cancer, and melanoma. Studies are evaluating novel treatment combinations and maintenance therapies for improved patient outcomes.

Advanced/Metastatic Breast Cancer Treatments
Urothelial Cancer Therapies
Hematologic Malignancies

Multiple trials are investigating innovative approaches for both solid tumors and blood cancers, with particular emphasis on targeted therapies.

02 Hematologic Disorders

Comprehensive studies examining treatments for various blood disorders, including chronic myeloid leukemia, myelofibrosis, and lymphomas. Focus on developing targeted therapies and combination treatments.

B-Cell Lymphoma Treatments
Myelofibrosis Therapies
Leukemia Management

Research aims to improve treatment outcomes and quality of life for patients with blood disorders.

03 Metabolic and Surgical Studies

Research initiatives addressing obesity management and surgical conditions like appendicitis. Studies include weight management therapies and surgical technique improvements.

Weight Management Interventions
Surgical Techniques
Prevention Studies

Trials focus on both therapeutic and surgical interventions for better patient outcomes.

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