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Clinical trials in Karlsruhe – page 6

128 clinical trials in Karlsruhe, Germany across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Karlsruhe at a glance
128
clinical trials
  • Research sites1
Type of trial
Recruitment status
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128 trials in Karlsruhe

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Overweight

Not yet recruiting

Study of Orforglipron in Overweight Adults at Risk of Developing Obesity‑Related Complications or Class 1 Obesity

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Sponsor:Eli Lilly & Co.

Influenza

Not yet recruiting

A Phase 3 Study of Efitazanamivir Alfa for Preventing Influenza in Adults and Adolescents at High Risk of Complications

Investigational
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years · 65+ years

Acute lymphocytic leukaemia

Not yet recruiting

Study of blinatumomab plus drug combination in children and adolescents with acute lymphoblastic leukemia

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Blinatumomab
  • Sponsor:Universitaetsklinikum Schleswig-Holstein AöR

Chronic kidney disease

Not yet recruiting

A study to evaluate the effect of survodutide on protein levels in the urine for patients with chronic kidney disease

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:BI 456906
  • Sponsor:Universitair Medisch Centrum Groningen

K-ras gene mutation+2

Not yet recruiting

Study of divarasib and pembrolizumab compared to standard chemotherapy in previously untreated KRAS G12C-mutated advanced non-small cell lung cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:F. Hoffmann-La Roche AG

Medulloblastoma

Not yet recruiting

Comparing two treatment regimens with drug combination for newly diagnosed low-risk medulloblastoma to evaluate cognitive function outcomes

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Carboplatin
  • Sponsor:GPOH gGmbH

Diffuse large B-cell lymphoma+2

Not yet recruiting

Study of Loncastuximab Tesirine and Epcoritamab for Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma, High-grade B-cell Lymphoma, or Follicular Lymphoma Grade 3B

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Epcoritamab
  • Sponsor:Universitaet Muenster

Study on Datopotamab Deruxtecan and Rilvegostomig for Stage I Non-Small Cell Lung Cancer Patients with ctDNA-Positive or High-Risk Features

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:AstraZeneca AB

Breast cancer female

Not yet recruiting

Study of Atezolizumab, Pertuzumab, and Trastuzumab for Patients with HER2 Positive Early High-Risk and Locally Advanced Breast Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Atezolizumab
  • Sponsor:Fondazione Michelangelo

Acute myeloid leukaemia

Not yet recruiting

Study on Treating Acute Myeloid Leukemia in Children and Adolescents Using CPX-351, Gemtuzumab Ozogamicin, and a Drug Combination

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years
  • Substances:Busulfan
  • Sponsor:GPOH gGmbH

Acute myeloid leukaemia+1

Not yet recruiting

Study of Cytarabine and Daunorubicin for Treating Myeloid Leukemia in Children with Down Syndrome

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years
  • Substances:Cytarabine
  • Sponsor:GPOH gGmbH

Neuroblastoma

Not yet recruiting

Study on Melphalan and Drug Combination for Low and Intermediate Risk Neuroblastoma Patients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:0–17 years · 18–64 years
  • Substances:Busulfan
  • Sponsor:University Of Cologne

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Clinical research in Karlsruhe

What the registry says about research in the country

01 Oncology Research

Extensive research focusing on colorectal cancer, breast cancer, and various types of lymphomas. Studies evaluate novel combination therapies and targeted treatments for patients with different stages of disease.

  • Metastatic colorectal cancer treatments
  • Triple-negative breast cancer therapy
  • B-cell lymphoma interventions

Advanced trials exploring immunotherapy combinations and precision medicine approaches.

02 Hematologic Malignancies

Groundbreaking studies in acute myeloid leukemia and chronic lymphocytic leukemia, testing innovative drug combinations and targeted therapies.

  • Novel AML treatment combinations
  • CLL/SLL therapeutic approaches
  • Multiple myeloma interventions

Focus on improving survival rates through personalized treatment strategies.

03 Chronic Conditions

Research addressing chronic kidney disease, pulmonary diseases, and metabolic disorders. Studies evaluate new therapeutic options for managing long-term health conditions.

  • COPD treatment innovations
  • Kidney disease management
  • Sleep apnea interventions

Emphasis on improving quality of life and disease outcomes.

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