Study on the Effectiveness of Inavolisib with Trastuzumab and Pertuzumab for Patients with HER2-Positive, HR-Positive, PIK3CA Mutant Early Breast Cancer

Registered drugNo placebo

Study on the Effectiveness of Inavolisib with Trastuzumab and Pertuzumab for Patients with HER2-Positive, HR-Positive, PIK3CA Mutant Early Breast Cancer

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Inavolisib
Sponsor:GBG Forschungs GmbH

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Clinical research in Kiel

What the registry says about research in the country

01 Oncology Research

Innovative clinical trials focusing on breast cancer treatments, including studies of ribociclib with endocrine therapy for HR-positive, HER2-negative cases. Additional research encompasses various blood cancers, including lymphomas and leukemia.

Early-stage breast cancer therapy
Diffuse large B-cell lymphoma treatments
Acute myeloid leukemia management

Cutting-edge research evaluating novel therapeutic combinations and treatment approaches for better patient outcomes.

02 Dermatological Studies

Comprehensive research into chronic skin conditions, including trials for plaque psoriasis and atopic dermatitis. Studies evaluate new therapeutic agents for moderate to severe cases.

Hidradenitis suppurativa treatments
Novel psoriasis therapies
Atopic dermatitis management

Focus on developing effective treatments for persistent skin conditions that significantly impact quality of life.

03 Gastrointestinal Research

Advanced studies in inflammatory bowel diseases, particularly Crohn's disease and ulcerative colitis. Trials investigate innovative therapies for moderate to severe cases.

Long-term disease management
Combination therapy approaches
Treatment-resistant cases

Investigation of new therapeutic options for patients with inadequate response to conventional treatments.

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Clinical trials in Kiel – page 14

433 trials in Kiel

Hormone receptor positive breast cancer+2

Study on Ribociclib and Drug Combination for Patients with Advanced HER2-Negative, Hormone Receptor Positive Breast Cancer

Parkinson's disease

Study on the Safety and Effects of ACI-7104.056 in Patients with Early Parkinson's Disease

Acute lymphocytic leukaemia

Study on Methotrexate and Dexamethasone for Infants Under One Year with Acute Lymphoblastic Leukemia

Anaplastic large cell lymphoma T- and null-cell types

Study on Vinblastine for Children and Adolescents with Standard Risk ALK-Positive Anaplastic Large Cell Lymphoma

Allogenic stem cell transplantation

Study on MaaT033 to Prevent Complications in Patients with Blood Cancer Undergoing Stem Cell Transplantation

Ewing's sarcoma

Study on Ewing Sarcoma Treatment with Vinorelbine and Drug Combination for Patients with Primary and Disseminated Disease

Alpha-1 antitrypsin deficiency

Study on Fazirsiran for Patients with Alpha-1 Antitrypsin Deficiency-Related Liver Disease and Fibrosis

Malignant melanoma

Study to Compare Fianlimab and Cemiplimab Combination with Pembrolizumab in Patients with High-Risk Melanoma After Surgery

Atypical teratoid/rhabdoid tumour of CNS

Study on Atypical Teratoid/Rhabdoid Tumors in Children Using Dactinomycin, Carboplatin, and Cyclophosphamide

Marginal zone lymphoma refractory

Study Comparing Mosunetuzumab and Lenalidomide with Other Treatments for Patients with Relapsed or Refractory Marginal Zone Lymphoma

Metastatic malignant melanoma+1

Study of Tebentafusp and Pembrolizumab for Patients with Previously Treated Advanced Melanoma

Breast cancer

Study on the Effectiveness of Inavolisib with Trastuzumab and Pertuzumab for Patients with HER2-Positive, HR-Positive, PIK3CA Mutant Early Breast Cancer

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