Clinical trials in Leiden – page 29

406 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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406

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406 trials in Leiden

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Uveal melanoma+2

Not recruiting

Study on the Effectiveness and Safety of Belzupacap Sarotalocan for Patients with Small Choroidal Melanoma or Indeterminate Lesions

Investigational

Study on the Effectiveness and Safety of Belzupacap Sarotalocan for Patients with Small Choroidal Melanoma or Indeterminate Lesions

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Belzupacap Sarotalocan
Sponsor:Aura Biosciences Inc.

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Chronic lymphocytic leukaemia

Not recruiting

Study on Obinutuzumab and Venetoclax for Elderly Patients with Chronic Lymphocytic Leukemia Unfit for Standard Treatments

Registered drugNo placebo

Study on Obinutuzumab and Venetoclax for Elderly Patients with Chronic Lymphocytic Leukemia Unfit for Standard Treatments

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Obinutuzumab
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Type IIa hyperlipidaemia

Not recruiting

Study on the Effectiveness of Enlicitide Chloride in Reducing Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease

Investigational

Study on the Effectiveness of Enlicitide Chloride in Reducing Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Merck Sharp & Dohme LLC

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Escherichia urinary tract infection

Not recruiting

Study of ExPEC9V vaccine for preventing invasive E.

Investigational

Study of ExPEC9V vaccine for preventing invasive E.

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:ECOO15
Sponsor:Janssen Vaccines & Prevention B.V.

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Eosinophilic granulomatosis with polyangiitis

Not recruiting

Study on the Effectiveness and Safety of Depemokimab vs. Mepolizumab for Adults with Relapsing or Refractory Eosinophilic Granulomatosis with Polyangiitis

Registered drug

Study on the Effectiveness and Safety of Depemokimab vs. Mepolizumab for Adults with Relapsing or Refractory Eosinophilic Granulomatosis with Polyangiitis

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Depemokimab
Sponsor:Glaxosmithkline Research & Development Limited

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Adenocarcinoma gastric

Not recruiting

Study on the Effectiveness of Paclitaxel, Docetaxel, and Oxaliplatin in Patients with Resectable Gastric Cancer

Registered drugNo placebo

Study on the Effectiveness of Paclitaxel, Docetaxel, and Oxaliplatin in Patients with Resectable Gastric Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Malignant melanoma+1

Not recruiting

Study Comparing Ipilimumab and Nivolumab with Standard Nivolumab for Patients with Stage III Melanoma

Registered drugNo placebo

Study Comparing Ipilimumab and Nivolumab with Standard Nivolumab for Patients with Stage III Melanoma

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Ipilimumab
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Oesophageal squamous cell carcinoma

Not recruiting

Study on Bintrafusp Alfa with Chemoradiation for Patients with Esophageal Squamous Cell Carcinoma

InvestigationalNo placebo

Study on Bintrafusp Alfa with Chemoradiation for Patients with Esophageal Squamous Cell Carcinoma

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bintrafusp Alfa
Sponsor:Amsterdam UMC Stichting

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Cardiac operation

Not recruiting

Study on Preventing Acute Kidney Injury in Cardiac Surgery Patients Using Dapagliflozin

Registered drugNo placebo

Study on Preventing Acute Kidney Injury in Cardiac Surgery Patients Using Dapagliflozin

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Dapagliflozin
Sponsor:Amsterdam UMC Stichting

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Prophylaxis against transplant rejection

Not recruiting

Study on the Safety of TX200-TR101 for Preventing Kidney Transplant Rejection in Patients Receiving a Living Donor Transplant

InvestigationalNo placebo

Study on the Safety of TX200-TR101 for Preventing Kidney Transplant Rejection in Patients Receiving a Living Donor Transplant

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:TX200-TR101
Sponsor:Sangamo Therapeutics France

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Myasthenia gravis

Not recruiting

Study on Vimseltinib for Patients with Tenosynovial Giant Cell Tumor

Investigational

Study on Vimseltinib for Patients with Tenosynovial Giant Cell Tumor

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Vimseltinib
Sponsor:Deciphera Pharmaceuticals Inc.

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C3 glomerulopathy

Not recruiting

Study on the Effectiveness and Safety of Iptacopan for Patients with Complement 3 Glomerulopathy

Investigational

Study on the Effectiveness and Safety of Iptacopan for Patients with Complement 3 Glomerulopathy

Investigational

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Iptacopan
Sponsor:Novartis Pharma AG

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Clinical research in Leiden

What the registry says about research in the country

01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

Influenza vaccine efficacy in elderly
Yellow fever prophylaxis
Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

Parkinson's Disease treatments
CNS response analysis
Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

Advanced solid tumors
Gastric cancer diagnosis
Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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