Innovative clinical trials focusing on advanced cancer treatments, including studies for endometrial carcinoma, bladder cancer, and various solid tumors. Current research explores combination therapies with novel immunotherapy approaches.

Triple-negative breast cancer treatments
Gastric and esophageal cancer therapies
Advanced pancreatic adenocarcinoma

Multiple studies are evaluating targeted therapies and immunological approaches for various tumor types.

02 Immunology and Infectious Diseases

Groundbreaking research in immune system modulation and infectious disease prevention, including studies on COVID-19 vaccines and immune response in critical conditions.

Novel COVID-19 intranasal vaccine development
Yellow fever vaccine studies
ICU-acquired immunosuppression treatment

Focus on developing innovative vaccination strategies and immune system interventions.

03 Chronic Conditions

Studies addressing long-term health conditions, with particular emphasis on kidney disease, cardiovascular health, and metabolic disorders.

Chronic kidney disease management
Heart failure prevention
Hypertriglyceridemia treatment

Innovative approaches combining established and experimental treatments for improved patient outcomes.

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Clinical trials in Lyon – page 8

1 204 trials in Lyon

Lymphogranuloma venereum

Doxycycline for Asymptomatic Anal LGV Infection in Patients with Asymptomatic Anal LGV Infection

Systemic lupus erythematosus

Nipocalimab in Adults with Moderate to Severe Systemic Lupus Erythematosus

Neoplasm

Telisotuzumab Adizutecan for Locally Advanced or Metastatic Solid Tumors with MET Amplification in Patients 12 Years and Older

Chronic myeloid leukaemia

Long-Term Safety Study of Asciminib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Neuroendocrine carcinoma

Obrixtamig, Carboplatin, and Etoposide for First-Line Treatment of Advanced Extrapulmonary Neuroendocrine Carcinoma in DLL3-Positive Patients

Obesity

RO7795068 for Weight Loss in Adults With Obesity or Overweight and Type 2 Diabetes

Fallopian tube cancer+2

Phase 3 Study of LY4170156 (Sofetabart Mipitecan) with drug combination in platinum‑resistant and platinum‑sensitive ovarian cancer patients

Dry age-related macular degeneration

FWY003 in Geographic Atrophy Secondary to Age-Related Macular Degeneration in Patients

IgA nephropathy

Long-Term Safety Study of Zigakibart in Adults with IgA Nephropathy Who Have Completed Previous Zigakibart Trials

Kidney transplant rejection

Frexalimab versus Tacrolimus for Prevention of Kidney Transplant Rejection in Adult Kidney Transplant Recipients

Acute promyelocytic leukaemia

Treatment Study of Arsenic Trioxide, Tretinoin, and Gemtuzumab Ozogamicin for Children and Adolescents with Acute Promyelocytic Leukemia

Immunoglobulin G4 related disease

A study to evaluate the efficacy and safety of rilzabrutinib in adults with active IgG4-related disease

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