Clinical trials in Milan – page 23

2 423 clinical trials in Milan, Italy across 15 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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2 423 trials in Milan

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Non-small cell lung cancer

Recruiting

A study of MK-1084 and a drug combination for patients with advanced or metastatic non-small cell lung cancer with KRAS G12C mutations.

Registered drugNo placebo

A study of MK-1084 and a drug combination for patients with advanced or metastatic non-small cell lung cancer with KRAS G12C mutations.

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Cetuximab
Sponsor:Merck Sharp & Dohme LLC

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Hereditary angioedema

Recruiting

A study of donidalorsen for children with hereditary angioedema

InvestigationalNo placebo

A study of donidalorsen for children with hereditary angioedema

InvestigationalNo placebo

Italy

Participants:0–17 years
Substances:Donidalorsen
Sponsor:Ionis Pharmaceuticals Inc.

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Cataract

Recruiting

Comparing the effectiveness of nepafenac and dexamethasone sodium phosphate for treating eye inflammation after cataract surgery

Registered drugNo placebo

Comparing the effectiveness of nepafenac and dexamethasone sodium phosphate for treating eye inflammation after cataract surgery

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Nepafenac
Sponsor:Medivis S.r.l.

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Chronic kidney disease+1

Recruiting

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

Italy

Participants:18–64 years · 65+ years
Sponsor:Eli Lilly & Co.

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Colitis ulcerative

Recruiting

A study to evaluate the efficacy and safety of etrasimod arginine in children with moderately to severely active ulcerative colitis

InvestigationalNo placebo

A study to evaluate the efficacy and safety of etrasimod arginine in children with moderately to severely active ulcerative colitis

InvestigationalNo placebo

Italy

Participants:0–17 years
Substances:Etrasimod Arginine
Sponsor:Pfizer Inc.

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Breast cancer metastatic

Recruiting

A study of palazestrant and ribociclib compared to letrozole and ribociclib for patients with advanced ER+ HER2- breast cancer

Registered drug

A study of palazestrant and ribociclib compared to letrozole and ribociclib for patients with advanced ER+ HER2- breast cancer

Registered drug

Italy

Participants:18–64 years · 65+ years
Substances:Letrozole
Sponsor:Olema Pharmaceuticals Inc.

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Fungal infection

Recruiting

A study to compare the effectiveness of EL219 against liposomal amphotericin B and voriconazole for patients with suspected invasive mould infections.

Registered drug

A study to compare the effectiveness of EL219 against liposomal amphotericin B and voriconazole for patients with suspected invasive mould infections.

Registered drug

Italy

Participants:18–64 years · 65+ years
Substances:Amphotericin B
Sponsor:Elion Therapeutics Inc.

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Polyneuropathy

Recruiting

A study to evaluate the safety and effectiveness of nucresiran and vutrisiran in patients with hereditary transthyretin amyloidosis with polyneuropathy

Registered drugNo placebo

A study to evaluate the safety and effectiveness of nucresiran and vutrisiran in patients with hereditary transthyretin amyloidosis with polyneuropathy

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Vutrisiran
Sponsor:Alnylam Pharmaceuticals Inc.

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Myasthenia gravis

Recruiting

A study to evaluate the safety and effectiveness of empasiprubart and efgartigimod alfa in patients with generalized myasthenia gravis.

InvestigationalNo placebo

A study to evaluate the safety and effectiveness of empasiprubart and efgartigimod alfa in patients with generalized myasthenia gravis.

InvestigationalNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Efgartigimod Alfa
Sponsor:Argenx

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Myasthenia gravis

Recruiting

A study of IM-101 in adults with generalized myasthenia gravis or ocular myasthenia gravis

Registered drug

A study of IM-101 in adults with generalized myasthenia gravis or ocular myasthenia gravis

Registered drug

Italy

Participants:18–64 years · 65+ years
Substances:IM-101
Sponsor:Immunabs Inc.

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K-ras gene mutation+1

Recruiting

A study of pembrolizumab, cetuximab, and MK-1084 for patients with advanced or metastatic non-small cell lung cancer with KRAS G12C mutations

Registered drugNo placebo

A study of pembrolizumab, cetuximab, and MK-1084 for patients with advanced or metastatic non-small cell lung cancer with KRAS G12C mutations

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Merck Sharp & Dohme LLC

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Mantle cell lymphoma

Recruiting

A study to evaluate the effectiveness of pirtobrutinib in elderly and frail patients with mantle cell lymphoma who have not yet received treatment.

Registered drugNo placebo

A study to evaluate the effectiveness of pirtobrutinib in elderly and frail patients with mantle cell lymphoma who have not yet received treatment.

Registered drugNo placebo

Italy

Participants:65+ years
Substances:Pirtobrutinib
Sponsor:Fondazione Italiana Linfomi Ets

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Clinical research in Milan

What the registry says about research in the country

01 Oncology Research

Innovative clinical trials focusing on colorectal cancer, breast cancer prevention, and advanced solid tumors. Studies include evaluation of novel therapeutic approaches and diagnostic methods.

Metastatic Colorectal Cancer Treatment
Breast Cancer Prevention Strategies
Advanced Solid Malignancies

Research emphasizes personalized treatment approaches and preventive interventions for high-risk patients.

02 Neurological Disorders

Research initiatives targeting neurodegenerative conditions and chronic headache disorders, with studies examining innovative therapeutic approaches.

Frontotemporal Dementia
Parkinson's Disease
Migraine Treatment

Focus on developing targeted therapies and understanding disease mechanisms.

03 Immunology and Infectious Diseases

Studies investigating treatments for autoimmune conditions and infectious diseases, including preventive approaches and therapeutic interventions.

Immune Thrombocytopenia
RSV Prevention
HIV Prevention

Emphasis on developing novel preventive strategies and therapeutic solutions.

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