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Clinical trials in Negrar di Valpolicella – page 2

71 clinical trials in Negrar di Valpolicella, Italy across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Negrar di Valpolicella at a glance
71
clinical trials
  • Paediatric trials0
  • Research sites1
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71 trials in Negrar di Valpolicella

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Testing icotrokinra compared to placebo for adults and adolescents with moderately to severely active ulcerative colitis

Investigational
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

Study of ONL1204 eye injections to slow vision loss in patients with age-related macular degeneration and geographic atrophy

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Xelafaslatide
  • Sponsor:ONL Therapeutics Inc.

Study of 177Lu-FAP-2286 alone and with drug combinations for patients with advanced solid tumors including non-small cell lung cancer, breast cancer, and pancreatic cancer

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Novartis Pharma AG

Study of RO7837195 injection compared to placebo to treat moderate to severe ulcerative colitis

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:RO7837195
  • Sponsor:Genentech Inc.

Study on Cetuximab and Drug Combination for Patients with Metastatic Colorectal Cancer

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Gruppo Oncologico Dell'Italia Meridionale

Crohn's disease

Recruiting

Study on the Effectiveness and Safety of RO7790121 for Patients with Moderate to Severe Crohn's Disease

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:RO7790121
  • Sponsor:F. Hoffmann-La Roche AG

Crohn's disease

Recruiting

Study on the Effectiveness and Safety of Obefazimod for Patients with Moderate to Severe Crohn's Disease After Inadequate Response to Other Treatments

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Obefazimod
  • Sponsor:Abivax

Study on Tedopi and Nivolumab for Patients with Advanced Non-Small Cell Lung Cancer After Initial Treatment

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:MPS-102
  • Sponsor:Fondazione Ricerca Traslazionale

Study Comparing Atezolizumab Alone and Atezolizumab with Bevacizumab for First-Line Treatment in Patients with Advanced Non-Small-Cell Lung Cancer

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Atezolizumab
  • Sponsor:Fondazione Ricerca Traslazionale

Study on Elacestrant and Everolimus for Patients with Advanced ER+/HER2- Breast Cancer Resistant to Endocrine Therapy and CDK4/6 Inhibitors

Registered drug
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Elacestrant
  • Sponsor:Medica Scientia Innovation Research S.L.

Study on Long-Term Safety of Ranibizumab for Patients with Wet Age-Related Macular Degeneration Using a Port Delivery System

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Ranibizumab
  • Sponsor:F. Hoffmann-La Roche AG

Study on Lutetium (177Lu) Vipivotide Tetraxetan to Delay Recurrence in Adult Men with PSMA-Positive Oligometastatic Prostate Cancer

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Gozetotide
  • Sponsor:Novartis Pharma AG

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Clinical research in Negrar di Valpolicella

What the registry says about research in the country

01 Oncology

Clinical research in Negrar di Valpolicella is strongly focused on breast cancer, prostate cancer, lung cancer, and other advanced solid tumors, with studies spanning both early and metastatic disease.

  • Testing new treatment strategies for HER2-positive and ER-positive breast cancer
  • Evaluating therapies for prostate cancer, including high-risk and metastatic forms
  • Studying treatment options for non-small cell lung cancer and pancreatic cancer
  • Exploring improved cancer control, relapse prevention, and survival outcomes

These trials aim to refine cancer care by comparing new approaches with standard treatments and identifying more effective options for patients.

02 Gastroenterology and Digestive Diseases

A major area of research centers on inflammatory bowel disease, especially Crohn’s disease and ulcerative colitis, alongside related digestive conditions.

  • Investigating therapies for moderately to severely active Crohn’s disease
  • Studying treatment approaches for ulcerative colitis
  • Addressing difficult subtypes such as fibrostenotic and fistulizing Crohn’s disease
  • Assessing maintenance of remission and long-term disease control

Many of these studies focus on easing symptoms, improving endoscopic outcomes, and helping patients achieve more durable remission.

03 Ophthalmology

Eye research in this city includes studies on age-related macular degeneration, especially neovascular AMD and geographic atrophy.

  • Testing new therapies for wet age-related macular degeneration
  • Evaluating options for atrophic age-related macular degeneration
  • Studying vision-preserving approaches and treatment durability
  • Exploring improved delivery systems for ocular therapy

The goal is to preserve sight, slow disease progression, and improve convenience for people living with chronic retinal disease.

04 Urology and Genitourinary Oncology

Several trials examine prostate cancer across localized, oligometastatic, and castration-resistant stages, reflecting a broad interest in genitourinary cancer care.

  • Studying treatment for high-risk localized prostate cancer
  • Assessing care for oligometastatic and metastatic castration-resistant disease
  • Using advanced imaging to improve detection of spread
  • Evaluating ways to delay progression and improve quality of life

These studies are designed to support earlier intervention and more precise treatment selection for patients with prostate cancer.

05 Breast Cancer Research

Breast cancer remains one of the most active fields of investigation, with trials covering early-stage, locally advanced, and metastatic breast cancer.

  • Testing therapies for HER2-positive, HER2-low, and HER2-negative disease
  • Studying ESR1-mutated and node-positive breast cancer
  • Exploring adjuvant and neoadjuvant treatment strategies
  • Aiming to improve response rates and reduce recurrence risk

Research in this area is centered on finding more personalized approaches that can better match treatment to tumor biology.

06 Respiratory Diseases and Lung Cancer

Trials in respiratory medicine focus mainly on non-small cell lung cancer, including advanced and recurrent disease, with some work also touching on infection-related respiratory conditions.

  • Evaluating new options for advanced non-small cell lung cancer
  • Studying treatments for recurrent or metastatic lung cancer
  • Exploring targeted and immune-based approaches
  • Supporting better disease control in hard-to-treat cases

This research aims to improve outcomes where current treatments may not be enough on their own.

07 Immunology and Autoimmune Diseases

Another important area involves immune-mediated diseases, especially inflammatory bowel disease and related immune system disorders.

  • Studying immune-targeted therapies for Crohn’s disease and ulcerative colitis
  • Examining inflammation control and mucosal healing
  • Assessing long-term safety of immune-modulating treatments
  • Looking at ways to maintain remission over time

These trials are aimed at improving symptom control while reducing the burden of chronic immune-related disease.

08 Cardiovascular and Stroke Prevention

Research in cardiovascular disease includes studies aimed at preventing recurrent events after ischemic stroke or transient ischemic attack.

  • Testing new approaches to reduce stroke recurrence
  • Evaluating balance between clot prevention and bleeding risk
  • Supporting secondary prevention after acute vascular events

These trials are focused on safer, more effective ways to protect patients at high risk of another cerebrovascular event.

09 Diagnostic Imaging and Investigative Techniques

Several studies in Negrar di Valpolicella use advanced diagnostic techniques to improve disease detection, staging, and treatment monitoring.

  • Assessing imaging tools for prostate cancer and metastatic spread
  • Studying methods that better identify response to therapy
  • Supporting more accurate diagnosis in oncology and eye disease
  • Helping guide treatment decisions with more reliable data

These projects reflect a strong interest in precision diagnostics and in tools that can make clinical care more tailored and timely.

10 Virus Diseases and Vaccination

Some trials address virus diseases, including studies related to respiratory syncytial virus, with a focus on immune protection in older adults.

  • Evaluating the immune response to RSV vaccination
  • Studying protection in adults aged 60 and older
  • Looking at vaccine safety and sustained immune benefit

These studies aim to strengthen prevention against seasonal respiratory infection in vulnerable populations.

11 Other Digestive and Metabolic Conditions

Additional research includes cholestatic and other digestive-related conditions, broadening the city’s profile beyond the main cancer and bowel disease programs.

  • Studying symptoms linked to cholestasis and related liver-bile disorders
  • Exploring ways to improve comfort and disease management
  • Supporting longer-term treatment tolerability

These trials add to a diverse research environment that combines common chronic diseases with more specialized clinical questions.

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