Clinical trials in Nijmegen – page 13

581 clinical trials in Nijmegen, The Netherlands across 7 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Our site in the NetherlandsKlinischOnderzoek.nl

Nijmegen at a glance

581

clinical trials

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581 trials in Nijmegen

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Tuberculosis

Recruiting

Study on High-Dose Rifampicin Safety for Adults with Complex Tuberculosis Using Isoniazid, Pyrazinamide, and Ethambutol Combination

Registered drugNo placebo

Study on High-Dose Rifampicin Safety for Adults with Complex Tuberculosis Using Isoniazid, Pyrazinamide, and Ethambutol Combination

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Isoniazid
Sponsor:Fundacio Hospital Universitari Vall D’Hebron Institut De Recerca

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Paroxysmal nocturnal haemoglobinuria

Recruiting

Study on Optimizing Ravulizumab Dosing for Adults with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Registered drugNo placebo

Study on Optimizing Ravulizumab Dosing for Adults with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ravulizumab
Sponsor:Stichting Radboud universitair medisch centrum

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Breast cancer

Recruiting

Study of olaparib and chemotherapy combination in stage III breast cancer patients with HER2-negative, hormone receptor impaired or deficient disease

Registered drugNo placebo

Study of olaparib and chemotherapy combination in stage III breast cancer patients with HER2-negative, hormone receptor impaired or deficient disease

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Subarachnoid haemorrhage

Recruiting

Study on Deferoxamine for Patients with Aneurysmal Subarachnoid Hemorrhage

Registered drug

Study on Deferoxamine for Patients with Aneurysmal Subarachnoid Hemorrhage

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Deferoxamine Mesilate
Sponsor:Stichting Radboud universitair medisch centrum

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Malignant melanoma

Recruiting

Study on Stopping Nivolumab or Pembrolizumab in Advanced Melanoma Patients After Achieving a Response

Registered drugNo placebo

Study on Stopping Nivolumab or Pembrolizumab in Advanced Melanoma Patients After Achieving a Response

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Nivolumab
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Hormone-refractory prostate cancer+1

Recruiting

Study of PF-06821497 and Enzalutamide for Men with Advanced Prostate Cancer Resistant to Hormone Therapy

Registered drug

Study of PF-06821497 and Enzalutamide for Men with Advanced Prostate Cancer Resistant to Hormone Therapy

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Enzalutamide
Sponsor:Pfizer Inc.

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Non-small cell lung cancer

Recruiting

Study of JNJ-90301900 with Chemoradiation and Durvalumab for Patients with Advanced Non-Small Cell Lung Cancer

InvestigationalNo placebo

Study of JNJ-90301900 with Chemoradiation and Durvalumab for Patients with Advanced Non-Small Cell Lung Cancer

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Hafnium oxide
Sponsor:Johnson & Johnson Enterprise Innovation Inc.

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Breast cancer

Recruiting

Study on Low-Dose Gadolinium for Breast Cancer MRI in Patients Using Gadoteric Acid

Registered drugNo placebo

Study on Low-Dose Gadolinium for Breast Cancer MRI in Patients Using Gadoteric Acid

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Gadoteric Acid
Sponsor:Stichting Radboud universitair medisch centrum

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Crohn's disease

Recruiting

Study on the Effectiveness and Safety of Vedolizumab and Upadacitinib in Adults with Moderate to Severe Crohn's Disease

Registered drug

Study on the Effectiveness and Safety of Vedolizumab and Upadacitinib in Adults with Moderate to Severe Crohn's Disease

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Upadacitinib
Sponsor:Takeda Development Center Americas Inc.

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Extra-osseous Ewing's sarcoma+5

Recruiting

Study of drug combination therapy for patients with recurrent and primary refractory Ewing Sarcoma

Registered drugNo placebo

Study of drug combination therapy for patients with recurrent and primary refractory Ewing Sarcoma

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Anhydrous Docetaxel
Sponsor:The University Of Birmingham

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Hypothyroidism

Recruiting

Study on Levothyroxine and Liothyronine for Patients with Autoimmune Hypothyroidism and Persistent Tiredness

Registered drug

Study on Levothyroxine and Liothyronine for Patients with Autoimmune Hypothyroidism and Persistent Tiredness

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Colorectal cancer

Recruiting

Study Comparing Amivantamab and Chemotherapy Versus Cetuximab and Chemotherapy for Patients with Advanced Colorectal Cancer

Registered drugNo placebo

Study Comparing Amivantamab and Chemotherapy Versus Cetuximab and Chemotherapy for Patients with Advanced Colorectal Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Amivantamab
Sponsor:Janssen Cilag International

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Clinical research in Nijmegen

What the registry says about research in the country

01 Neurological Studies

Research focusing on various brain conditions, including glioblastoma imaging techniques and treatments for status epilepticus. Studies investigate brain tissue infiltration patterns and post-cardiac arrest neural conditions.

Brain tumor visualization
Serotonin's role in decision-making
Post-trauma stress disorders

Advanced imaging techniques and therapeutic interventions are being evaluated to improve patient outcomes.

02 Cardiovascular Research

Comprehensive studies examining heart failure prevention and treatment approaches. Investigations include new drug combinations and preventive strategies for cardiovascular events.

Heart failure prevention
Cardiovascular disease management
Post-cardiac arrest care

Clinical trials focus on both preventive measures and acute treatment protocols.

03 Cancer Studies

Innovative research in oncology, particularly focusing on advanced treatment approaches for various cancer types, including breast cancer and leukemia.

Breast cancer imaging
Leukemia treatments
Gastric cancer therapies

Studies evaluate new therapeutic combinations and diagnostic techniques.

04 Metabolic Disorders

Research examining gestational diabetes and obesity treatments, with emphasis on innovative imaging techniques and therapeutic approaches.

Diabetes management
Obesity treatments
Metabolic imaging

Focus on developing personalized treatment strategies.

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