Clinical trials in Nijmegen – page 4

581 clinical trials in Nijmegen, The Netherlands across 7 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Nijmegen at a glance

581

clinical trials

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581 trials in Nijmegen

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Crohn's disease

Recruiting

A Phase 3b Study of Guselkumab Compared with Risankizumab in Adults with Moderately to Severely Active Crohn’s Disease

Registered drugNo placebo

A Phase 3b Study of Guselkumab Compared with Risankizumab in Adults with Moderately to Severely Active Crohn’s Disease

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Guselkumab
Sponsor:Janssen Cilag International

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Non-small cell lung cancer stage III

Recruiting

Pumitamig Versus Durvalumab in Patients With Unresectable Stage III Non-Small Cell Lung Cancer Without Progression After Chemoradiation

Registered drugNo placebo

Pumitamig Versus Durvalumab in Patients With Unresectable Stage III Non-Small Cell Lung Cancer Without Progression After Chemoradiation

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Durvalumab
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Plasma cell myeloma refractory

Recruiting

JNJ-79635322 versus Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma After at Least 3 Prior Treatments

InvestigationalNo placebo

JNJ-79635322 versus Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma After at Least 3 Prior Treatments

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Teclistamab
Sponsor:Janssen Cilag International

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Non-small cell lung cancer+1

Recruiting

Pumitamig Versus Pembrolizumab in Patients With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%

Registered drugNo placebo

Pumitamig Versus Pembrolizumab in Patients With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Pembrolizumab
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Dyslipidaemia

Recruiting

Comparison of Obicetrapib and Bempedoic Acid in Patients with Dyslipidemia at High to Very High Cardiovascular Risk

Registered drug

Comparison of Obicetrapib and Bempedoic Acid in Patients with Dyslipidemia at High to Very High Cardiovascular Risk

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bempedoic Acid

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Cervix carcinoma

Recruiting

Evaluation of pembrolizumab and bevacizumab in patients with metastatic cervical cancer

Registered drugNo placebo

Evaluation of pembrolizumab and bevacizumab in patients with metastatic cervical cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:Universitair Medisch Centrum Groningen

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Obesity

Recruiting

RO7795068 for Weight Loss in Adults With Obesity or Overweight Without Type 2 Diabetes

Investigational

RO7795068 for Weight Loss in Adults With Obesity or Overweight Without Type 2 Diabetes

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:F. Hoffmann-La Roche AG

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Inflammatory bowel disease+1

Recruiting

Modafinil for Severe Fatigue in Patients with Quiescent Inflammatory Bowel Disease

Registered drug

Modafinil for Severe Fatigue in Patients with Quiescent Inflammatory Bowel Disease

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Modafinil
Sponsor:Stichting Radboud universitair medisch centrum

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Myotonic dystrophy

Recruiting

A study to evaluate the efficacy and safety of DYNE-101 in patients with Myotonic Dystrophy Type 1

Registered drug

A study to evaluate the efficacy and safety of DYNE-101 in patients with Myotonic Dystrophy Type 1

Registered drug

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Humanised Igg1 Kappa Fragment Antibody Targeting Tfr1 Conjugated To P125 Oligonucleotide
Sponsor:Dyne Therapeutics Inc.

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Gastric cancer+4

Recruiting

A study to evaluate the use of [68Ga]BED003 for imaging colorectal, gastric, pancreatic, breast, and ovarian cancers.

InvestigationalNo placebo

A study to evaluate the use of [68Ga]BED003 for imaging colorectal, gastric, pancreatic, breast, and ovarian cancers.

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years

Contact Research Centre

HIV infection

Recruiting

A study to evaluate the effectiveness of lenalidomide, pyrimethamine, and topiramate in reducing the HIV reservoir in people living with HIV.

Registered drugNo placebo

A study to evaluate the effectiveness of lenalidomide, pyrimethamine, and topiramate in reducing the HIV reservoir in people living with HIV.

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Lenalidomide
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Progressive supranuclear palsy

Recruiting

A study to evaluate the safety and effectiveness of NIO752 in patients with progressive supranuclear palsy

Registered drug

A study to evaluate the safety and effectiveness of NIO752 in patients with progressive supranuclear palsy

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Sodium Chloride
Sponsor:Novartis Pharma AG

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Clinical research in Nijmegen

What the registry says about research in the country

01 Neurological Studies

Research focusing on various brain conditions, including glioblastoma imaging techniques and treatments for status epilepticus. Studies investigate brain tissue infiltration patterns and post-cardiac arrest neural conditions.

Brain tumor visualization
Serotonin's role in decision-making
Post-trauma stress disorders

Advanced imaging techniques and therapeutic interventions are being evaluated to improve patient outcomes.

02 Cardiovascular Research

Comprehensive studies examining heart failure prevention and treatment approaches. Investigations include new drug combinations and preventive strategies for cardiovascular events.

Heart failure prevention
Cardiovascular disease management
Post-cardiac arrest care

Clinical trials focus on both preventive measures and acute treatment protocols.

03 Cancer Studies

Innovative research in oncology, particularly focusing on advanced treatment approaches for various cancer types, including breast cancer and leukemia.

Breast cancer imaging
Leukemia treatments
Gastric cancer therapies

Studies evaluate new therapeutic combinations and diagnostic techniques.

04 Metabolic Disorders

Research examining gestational diabetes and obesity treatments, with emphasis on innovative imaging techniques and therapeutic approaches.

Diabetes management
Obesity treatments
Metabolic imaging

Focus on developing personalized treatment strategies.

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