Clinical trials in Palermo – page 4

384 clinical trials in Palermo, Italy across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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384 trials in Palermo

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Acute promyelocytic leukaemia

Recruiting

Treatment Study of Arsenic Trioxide, Tretinoin, and Gemtuzumab Ozogamicin for Children and Adolescents with Acute Promyelocytic Leukemia

Registered drugNo placebo

Treatment Study of Arsenic Trioxide, Tretinoin, and Gemtuzumab Ozogamicin for Children and Adolescents with Acute Promyelocytic Leukemia

Registered drugNo placebo

Italy

Participants:0–17 years
Substances:Arsenic Trioxide
Sponsor:Associazione Italiana Ematologia Oncologia Pediatrica

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A study to assess the safety of anumigilimab in adults with sickle cell disease

Recruiting

Investigational

A study to assess the safety of anumigilimab in adults with sickle cell disease

Investigational

Italy

Participants:18–64 years · 65+ years
Substances:Anumigilimab
Sponsor:CSL Behring LLC

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Cardiac failure+1

Recruiting

Study of Zenagamtide (NNC0487-0111) versus placebo in patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational

Study of Zenagamtide (NNC0487-0111) versus placebo in patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational

Italy

Participants:18–64 years · 65+ years
Sponsor:Novo Nordisk A/S

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Breast cancer+1

Recruiting

Maintenance Therapy Study of Inavolisib with Pertuzumab and Trastuzumab in Patients with HER2‑Positive, PIK3CA‑Mutated Locally Advanced or Metastatic Breast Cancer

Registered drug

Maintenance Therapy Study of Inavolisib with Pertuzumab and Trastuzumab in Patients with HER2‑Positive, PIK3CA‑Mutated Locally Advanced or Metastatic Breast Cancer

Registered drug

Italy

Participants:18–64 years · 65+ years
Substances:Anastrozole
Sponsor:F. Hoffmann-La Roche AG

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Mantle cell lymphoma

Recruiting

Study of glofitamab, obinutuzumab and tocilizumab in patients with mantle cell lymphoma relapsed or refractory after CAR‑T therapy

Registered drugNo placebo

Study of glofitamab, obinutuzumab and tocilizumab in patients with mantle cell lymphoma relapsed or refractory after CAR‑T therapy

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Glofitamab
Sponsor:Fondazione Italiana Linfomi Ets

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Bronchiectasis

Recruiting

A study to evaluate the safety and effectiveness of AZD0292 in people aged 12 years and older with bronchiectasis and chronic Pseudomonas aeruginosa infection

Investigational

A study to evaluate the safety and effectiveness of AZD0292 in people aged 12 years and older with bronchiectasis and chronic Pseudomonas aeruginosa infection

Investigational

Italy

Participants:18–64 years · 65+ years
Substances:AZD0292
Sponsor:AstraZeneca AB

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Interstitial lung disease+1

Recruiting

A study to evaluate the safety and effectiveness of inhaled treprostinil in patients with pulmonary hypertension associated with interstitial lung disease

Investigational

A study to evaluate the safety and effectiveness of inhaled treprostinil in patients with pulmonary hypertension associated with interstitial lung disease

Investigational

Italy

Participants:18–64 years · 65+ years
Substances:Treprostinil
Sponsor:Liquidia Technologies Inc.

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Cardiac function disturbance postoperative+1

Recruiting

A study to evaluate the effectiveness of R2R01 in preventing acute kidney injury in patients at high risk following heart surgery.

Registered drug

A study to evaluate the effectiveness of R2R01 in preventing acute kidney injury in patients at high risk following heart surgery.

Registered drug

Italy

Participants:18–64 years · 65+ years
Substances:R2R01
Sponsor:River 2 Renal Corp.

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Cataract

Recruiting

Comparing the effectiveness of nepafenac and dexamethasone sodium phosphate for treating eye inflammation after cataract surgery

Registered drugNo placebo

Comparing the effectiveness of nepafenac and dexamethasone sodium phosphate for treating eye inflammation after cataract surgery

Registered drugNo placebo

Italy

Participants:18–64 years · 65+ years
Substances:Nepafenac
Sponsor:Medivis S.r.l.

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Chronic kidney disease+1

Recruiting

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

Italy

Participants:18–64 years · 65+ years
Sponsor:Eli Lilly & Co.

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Mantle cell lymphoma

Recruiting

A study to evaluate the effectiveness of pirtobrutinib in elderly and frail patients with mantle cell lymphoma who have not yet received treatment.

Registered drugNo placebo

A study to evaluate the effectiveness of pirtobrutinib in elderly and frail patients with mantle cell lymphoma who have not yet received treatment.

Registered drugNo placebo

Italy

Participants:65+ years
Substances:Pirtobrutinib
Sponsor:Fondazione Italiana Linfomi Ets

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Clostridium difficile infection

Recruiting

A study to evaluate the effectiveness of AZD5148 in preventing the recurrence of Clostridioides difficile infection in adults.

Investigational

A study to evaluate the effectiveness of AZD5148 in preventing the recurrence of Clostridioides difficile infection in adults.

Investigational

Italy

Participants:18–64 years · 65+ years
Substances:AZD5148
Sponsor:AstraZeneca AB

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Clinical research in Palermo

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01 Oncology Research

Innovative clinical trials focusing on metastatic colorectal cancer treatments and novel approaches for multiple myeloma. Studies are evaluating targeted therapies for diffuse large B-cell lymphoma and investigating new treatment combinations for various cancer types.

Colorectal Cancer Treatment Strategies
Lymphoma Therapy Development
Multiple Myeloma Management

Advanced research includes evaluation of targeted therapies and immunotherapy combinations.

02 Cardiovascular Studies

Comprehensive research into heart failure prevention and cardiovascular disease management. Clinical trials are examining new therapeutic approaches for pulmonary arterial hypertension and innovative treatments for cardiovascular complications.

Heart Failure Prevention
Cardiovascular Risk Management
Hypertension Treatment

Focus on developing preventive strategies and novel therapeutic interventions.

03 Autoimmune Disorders

Groundbreaking research investigating treatments for multiple sclerosis and systemic sclerosis. Studies evaluate new biological therapies and innovative approaches for managing autoimmune conditions including psoriatic arthritis.

Multiple Sclerosis Therapies
Inflammatory Disease Management
Autoimmune Treatment Innovation

Emphasis on developing targeted therapies for various autoimmune conditions.

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