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Clinical trials in Pernik – page 3

39 clinical trials in Pernik, Bulgaria. Every trial is listed in the EU Clinical Trials Register and updated daily.

Pernik at a glance
39
clinical trials
  • Paediatric trials0
  • Research sites0
Type of trial
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39 trials in Pernik

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Study on the Effectiveness and Safety of AVP-786 (Quinidine Sulfate and Deudextromethorphan Hydrobromide) for Treating Agitation in Alzheimer's Dementia Patients

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Quinidine Sulfate
  • Sponsor:Otsuka Pharmaceutical Development & Commercialization Inc.

Arteriosclerosis

Not recruiting

Study of inclisiran to prevent heart attacks and strokes in people with atherosclerotic cardiovascular disease

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Atorvastatin
  • Sponsor:Novartis Pharma AG

Asthma

Not recruiting

Comparison of CHF5993 (glycopyrronium bromide, formoterol fumarate dihydrate, and beclometasone dipropionate) and a drug combination for patients with mild to moderate asthma

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Placebo
  • Sponsor:Chiesi Farmaceutici S.p.A.

Chronic kidney disease+1

Not recruiting

A study of ziltivekimab compared to placebo in people with heart and blood vessel disease, chronic kidney disease and inflammation

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Ziltivekimab
  • Sponsor:Novo Nordisk A/S

Arteriosclerosis

Not recruiting

Long-term safety study of pelacarsen in patients with atherosclerotic cardiovascular disease who completed the Lp(a)HORIZON trial

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Pelacarsen
  • Sponsor:Novartis Pharma AG

Asthmatic crisis

Not recruiting

Long-term safety and effectiveness study of verekitug injections in adults with severe asthma who completed the VALIANT trial

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Human IgG1 kappa monoclonal antibody against CRLF2
  • Sponsor:Upstream Bio Inc.

Study of AB-1002 gene therapy given through coronary arteries in adults with severe (NYHA Class III) heart failure caused by non-ischemic cardiomyopathy

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AB-1002
  • Sponsor:Askbio Inc.

Asthma

Not recruiting

Long-term safety study of dexpramipexole tablets in patients with severe eosinophilic asthma who completed EXHALE-2 or EXHALE-3 trials

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Dexpramipexole Dihydrochloride Monohydrate
  • Sponsor:Areteia Therapeutics Inc.

Asthma

Not recruiting

Study on the Effects of Dexpramipexole for Adolescents and Adults with Severe Eosinophilic Asthma

Investigational
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Dexpramipexole Dihydrochloride Monohydrate
  • Sponsor:Areteia Therapeutics Inc.

Asthma

Not recruiting

Study on the Effectiveness and Safety of Fluticasone Propionate and Salbutamol Sulfate for Patients with Asthma

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Salbutamol Sulfate
  • Sponsor:Teva Branded Pharmaceutical Products R&D LLC

Asthmatic crisis

Not recruiting

Study on the Effects of Verekitug (UPB-101) for Adults with Severe Asthma

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Human IgG1 kappa monoclonal antibody against CRLF2
  • Sponsor:Upstream Bio Inc.

Study on the Effectiveness and Safety of EDP-938 for Adults with High-Risk Respiratory Syncytial Virus (RSV) Infection

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Zelicapavir
  • Sponsor:Enanta Pharmaceuticals Inc.

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Clinical research in Pernik

What the registry says about research in the country

01 Respiratory Medicine

Innovative clinical research focusing on respiratory conditions, including studies of new treatments for severe asthma and COPD. Multiple trials are evaluating medications like verekitug and astegolimab to reduce disease exacerbations and improve patient outcomes.

  • Severe Asthma Management
  • COPD Treatment Advances
  • Respiratory Viral Infections

Several studies are exploring novel therapeutic approaches for patients with inadequate response to standard treatments.

02 Cardiovascular Research

Comprehensive studies targeting cardiovascular diseases, from acute myocardial infarction to stroke prevention. Trials are investigating innovative treatments like selatogrel for acute cardiac events and new approaches for atherosclerotic cardiovascular disease management.

  • Heart Attack Prevention
  • Stroke Risk Reduction
  • Atrial Fibrillation Treatment

Research focuses on both preventive measures and acute treatment strategies.

03 Chronic Disease Management

Groundbreaking research in chronic kidney disease and related conditions. Studies evaluate combination therapies and novel approaches for managing complex medical conditions including hypertension and urticaria.

  • Kidney Disease Therapy
  • Hypertension Management
  • Chronic Urticaria Treatment

Trials aim to improve long-term outcomes and quality of life for patients with chronic conditions.

04 Neurological Studies

Advanced research targeting Alzheimer's disease and associated symptoms. Clinical trials are evaluating new treatments for managing behavioral symptoms in dementia patients.

  • Dementia Management
  • Agitation Treatment
  • Behavioral Interventions

Focus on improving quality of life for patients and caregivers through innovative therapeutic approaches.

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