Clinical trials in Ruse – page 4

184 clinical trials in Ruse, Bulgaria. Every trial is listed in the EU Clinical Trials Register and updated daily.

Ruse at a glance

184

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184 trials in Ruse

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Ischaemic stroke

Recruiting

A study to evaluate the effectiveness of tenecteplase in patients with acute ischemic stroke who are more than 4.5 hours after their last known well time.

Registered drugNo placebo

A study to evaluate the effectiveness of tenecteplase in patients with acute ischemic stroke who are more than 4.5 hours after their last known well time.

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Tenecteplase
Sponsor:Boehringer Ingelheim International GmbH

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Chronic kidney disease+1

Recruiting

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Sponsor:Eli Lilly & Co.

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Systemic lupus erythematosus

Recruiting

Evaluation of Long-Term Safety and Efficacy of Litifilimab in Adults with Active Systemic Lupus Erythematosus: A Phase 3 Multicenter, Randomized, Dose-Blind Study

Investigational

Evaluation of Long-Term Safety and Efficacy of Litifilimab in Adults with Active Systemic Lupus Erythematosus: A Phase 3 Multicenter, Randomized, Dose-Blind Study

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Litifilimab
Sponsor:Biogen Idec Research Limited

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Chronic obstructive pulmonary disease

Recruiting

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

Registered drug

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Depemokimab
Sponsor:Glaxosmithkline Research & Development Limited

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Asthma

Recruiting

Testing WIN378 Safety and Effects in Adults with Moderate or Severe Asthma

Investigational

Testing WIN378 Safety and Effects in Adults with Moderate or Severe Asthma

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Human IgG1 monoclonal antibody against TSLP
Sponsor:Windward Bio AG

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Non-small cell lung cancer stage IV+2

Recruiting

A Study of BMS-986504 with Drug Combination Compared to Placebo with Drug Combination in Patients with Advanced Non-Small Cell Lung Cancer Starting First Treatment

Registered drug

A Study of BMS-986504 with Drug Combination Compared to Placebo with Drug Combination in Patients with Advanced Non-Small Cell Lung Cancer Starting First Treatment

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Dementia of the Alzheimer's type with delusions

Recruiting

A Study of fesoterodine and 5-[(1R,5R)-3-Azabicyclo[3.

Investigational

A Study of fesoterodine and 5-[(1R,5R)-3-Azabicyclo[3.

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Fesoterodine
Sponsor:Maplight Therapeutics Inc.

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Small cell lung cancer recurrent

Recruiting

Study comparing GSK5764227 and topotecan in adults with relapsed small cell lung cancer

Registered drugNo placebo

Study comparing GSK5764227 and topotecan in adults with relapsed small cell lung cancer

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:GSK5764227
Sponsor:Glaxosmithkline Research & Development Limited

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Major depression

Recruiting

Safety and Tolerability Study of NBI-1065845 as Additional Treatment for Adults with Major Depressive Disorder

InvestigationalNo placebo

Safety and Tolerability Study of NBI-1065845 as Additional Treatment for Adults with Major Depressive Disorder

InvestigationalNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:9-(4-CYCLOHEXYLOXYPHENYL)-7-METHYL-3,4-DIHYDROPYRAZINO[2,1-C][1,2,4]THIADIAZINE 2,2-DIOXIDE
Sponsor:Neurocrine Biosciences Inc.

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Hypertriglyceridaemia

Recruiting

Study of plozasiran to prevent acute pancreatitis in adults with severe hypertriglyceridemia

Investigational

Study of plozasiran to prevent acute pancreatitis in adults with severe hypertriglyceridemia

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Synthetic Double-Stranded Sirna Oligonucleotide Directed Against Apolipoprotein C-Iii Mrna And Covalently Linked To A Ligand Containing Three N-Acetylgalactosamine Residues
Sponsor:Arrowhead Pharmaceuticals Inc.

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Cardiac failure

Recruiting

Evaluating the Effect of Vicadrostat and Empagliflozin Combination Compared to Empagliflozin Alone in Patients with Heart Failure and Reduced Left Ventricular Function

Registered drug

Evaluating the Effect of Vicadrostat and Empagliflozin Combination Compared to Empagliflozin Alone in Patients with Heart Failure and Reduced Left Ventricular Function

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:BI 690517
Sponsor:Boehringer Ingelheim International GmbH

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Major depression

Recruiting

Assessment of NBI-1065845 as an Additional Treatment for Adults with Major Depressive Disorder

Investigational

Assessment of NBI-1065845 as an Additional Treatment for Adults with Major Depressive Disorder

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:9-(4-CYCLOHEXYLOXYPHENYL)-7-METHYL-3,4-DIHYDROPYRAZINO[2,1-C][1,2,4]THIADIAZINE 2,2-DIOXIDE
Sponsor:Neurocrine Biosciences Inc.

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Clinical research in Ruse

What the registry says about research in the country

01 Respiratory Diseases

Current clinical research focuses on asthma management and innovative treatments for respiratory conditions, including trials of new inhaler formulations and targeted therapies for uncontrolled asthma patients.

Asthma treatment optimization
Severe viral lung infections
Influenza prevention

Studies are evaluating both novel compounds and improved delivery systems for existing medications.

02 Cardiovascular Health

Breakthrough research in cardiovascular disease prevention and treatment, with particular attention to heart failure prevention and innovative approaches to managing cardiac conditions.

Heart failure prevention
Hypertrophic cardiomyopathy
Major cardiovascular events reduction

Multiple trials are exploring combination therapies and new molecular entities for cardiac conditions.

03 Immunology and Inflammation

Extensive research into psoriatic arthritis treatments, including both biologic-naive and biologic-experienced patient populations.

Psoriatic arthritis therapies
Prurigo nodularis treatment
Inflammatory conditions

Studies are evaluating novel therapeutic approaches for various inflammatory conditions.

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