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Clinical trials in Sibiu

55 clinical trials in Sibiu, Romania. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Sibiu at a glance
55
clinical trials
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55 trials in Sibiu

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Cardiovascular disorder+1

Recruiting

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Zilebesiran
  • Sponsor:Alnylam Pharmaceuticals Inc.

Urinary incontinence+1

Recruiting

Orforglipron for stress urinary incontinence in women with obesity or overweight

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years
  • Sponsor:Eli Lilly & Co.

Dementia Alzheimer's type

Recruiting

Study of trospium chloride and xanomeline tartrate combination for agitation in Alzheimer's disease patients: Long-term safety evaluation

InvestigationalNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Trospium Chloride
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Acute respiratory failure

Recruiting

Study on Tozorakimab for Patients Hospitalized with Severe Viral Lung Infections Needing Oxygen

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Tozorakimab
  • Sponsor:AstraZeneca AB

Schizophrenia

Recruiting

Study on Vafidemstat for Treating Negative Symptoms and Cognitive Impairment in Adults with Schizophrenia

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years
  • Substances:Vafidemstat
  • Sponsor:Oryzon Genomics S.A.

Graves' disease

Recruiting

Phase 3 Randomized Placebo‑Controlled Study of Efgartigimod Alfa in Adults with Graves’ Disease Inadequately Controlled by Antithyroid Drugs

Registered drug
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Efgartigimod Alfa
  • Sponsor:Argenx

Acute lymphocytic leukaemia

Recruiting

Study of blinatumomab and a drug combination for older adults with newly diagnosed Philadelphia-negative B-cell precursor Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Asparaginase
  • Sponsor:Amgen Inc.

Chronic kidney disease+1

Recruiting

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Sponsor:Eli Lilly & Co.

Myasthenia gravis

Recruiting

Study of oral cladribine compared to placebo for patients with generalized myasthenia gravis

Registered drug
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Cladribine
  • Sponsor:Merck Healthcare KGaA

Schizophrenia

Recruiting

A Study Testing Brexpiprazole Given Once Weekly to Treat Sudden Worsening of Symptoms in Patients with Schizophrenia

Registered drug
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Brexpiprazole
  • Sponsor:Otsuka Pharmaceutical Co. Ltd.

Crohn's disease

Recruiting

Study of icotrokinra for adults with moderately to severely active Crohn's disease

Investigational
Countries:RomaniaRomania
  • Participants:18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

Colitis ulcerative

Recruiting

Testing icotrokinra compared to placebo for adults and adolescents with moderately to severely active ulcerative colitis

Investigational
Countries:RomaniaRomania
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

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Clinical research in Sibiu

What the registry says about research in the country

01 Neurological Disorders

Innovative trials focusing on Myasthenia Gravis and various forms of Multiple Sclerosis, including studies evaluating new therapeutic approaches for disease management and symptom control.

  • Relapsing Multiple Sclerosis
  • Generalized Myasthenia Gravis
  • Episodic Migraine in Pediatrics

Several trials are investigating novel compounds to improve daily living activities and reduce disease progression.

02 Oncology Research

Comprehensive studies on various cancer types, with particular focus on Non-Small Cell Lung Cancer and Lymphoma treatments, including innovative combination therapies.

  • Large B-Cell Lymphoma
  • Chronic Myeloid Leukemia
  • Bladder Cancer
  • Early Breast Cancer

Advanced therapeutic approaches combining immunotherapy with standard treatments.

03 Mental Health Studies

Research initiatives addressing Major Depressive Disorder and Schizophrenia, with specialized focus on treatment-resistant cases and cognitive symptoms.

  • Depression with Anhedonia
  • Depression with Insomnia
  • Alzheimer's Disease Psychosis

Novel therapeutic approaches targeting specific symptoms and comorbidities.

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