Clinical trials in Sofia – page 26

772 clinical trials in Sofia, Bulgaria across 17 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Sofia at a glance

772

clinical trials

Research sites17

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772 trials in Sofia

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Bipolar I disorder

Not yet recruiting

A study to evaluate the effectiveness and safety of azetukalner in patients experiencing depressive episodes associated with bipolar disorder.

Investigational

A study to evaluate the effectiveness and safety of azetukalner in patients experiencing depressive episodes associated with bipolar disorder.

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Azetukalner
Sponsor:Xenon Pharmaceuticals Inc.

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Pancreatic carcinoma metastatic+1

Not yet recruiting

A Study of Ponsegromab Combined with Chemotherapy for Adults with Pancreatic Cancer that has Spread and Caused Weight Loss

Registered drug

A Study of Ponsegromab Combined with Chemotherapy for Adults with Pancreatic Cancer that has Spread and Caused Weight Loss

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Ponsegromab
Sponsor:Pfizer Inc.

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Conjunctivitis allergic+1

Not yet recruiting

A Study Comparing Tacrolimus and Ciclosporin Eye Drops for Children and Adults with Moderate to Severe Vernal Keratoconjunctivitis

Registered drugNo placebo

A Study Comparing Tacrolimus and Ciclosporin Eye Drops for Children and Adults with Moderate to Severe Vernal Keratoconjunctivitis

Registered drugNo placebo

Bulgaria

Participants:0–17 years
Substances:Ciclosporin
Sponsor:Laboratoires Thea

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Immune thrombocytopenia

Not yet recruiting

Study on the Safety and Effectiveness of Budoprutug in Patients with Immune Thrombocytopenia

InvestigationalNo placebo

Study on the Safety and Effectiveness of Budoprutug in Patients with Immune Thrombocytopenia

InvestigationalNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Budoprutug
Sponsor:Climb Bio Inc.

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Abdominal infection+5

Not yet recruiting

Study on Aztreonam, Avibactam, and Metronidazole for Treating Infections in Neonates and Infants Under 9 Months with Gram-Negative Bacterial Infections

Registered drugNo placebo

Study on Aztreonam, Avibactam, and Metronidazole for Treating Infections in Neonates and Infants Under 9 Months with Gram-Negative Bacterial Infections

Registered drugNo placebo

Bulgaria

Participants:0–17 years
Substances:Avibactam Sodium
Sponsor:Pfizer Inc.

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Prostate cancer

Not yet recruiting

Study Comparing Rezvilutamide and Bicalutamide with Hormone Therapy for Patients with Advanced Prostate Cancer

Registered drugNo placebo

Study Comparing Rezvilutamide and Bicalutamide with Hormone Therapy for Patients with Advanced Prostate Cancer

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Bicalutamide
Sponsor:Jiangsu Hengrui Pharmaceuticals Co. Ltd.

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Colitis ulcerative

Not yet recruiting

Study on the Safety and Effectiveness of Lutikizumab and Adalimumab for Adults with Moderate to Severe Ulcerative Colitis

Registered drugNo placebo

Study on the Safety and Effectiveness of Lutikizumab and Adalimumab for Adults with Moderate to Severe Ulcerative Colitis

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Adalimumab
Sponsor:AbbVie Deutschland GmbH & Co. KG

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Angina pectoris

Not yet recruiting

Study on the Effects of T89 and Glyceryl Trinitrate for Patients with Stable Angina

Registered drug

Study on the Effects of T89 and Glyceryl Trinitrate for Patients with Stable Angina

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Glyceryl Trinitrate
Sponsor:Tasly Pharmaceuticals Inc.

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Anaemia of chronic disease

Not yet recruiting

Study on Efepoetin Alfa and Darbepoetin Alfa for Treating Anemia in Patients with Chronic Kidney Disease on Dialysis

Registered drugNo placebo

Study on Efepoetin Alfa and Darbepoetin Alfa for Treating Anemia in Patients with Chronic Kidney Disease on Dialysis

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Darbepoetin Alfa
Sponsor:Genexine Inc.

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Magnetic resonance imaging

Not yet recruiting

Study on How Gadoquatrane Works and Its Safety in Children Undergoing MRI Scans

InvestigationalNo placebo

Study on How Gadoquatrane Works and Its Safety in Children Undergoing MRI Scans

InvestigationalNo placebo

Bulgaria

Participants:0–17 years
Substances:Gadoquatrane
Sponsor:Bayer AG

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Bacterial infection

Not yet recruiting

Study on Cefiderocol for Treating Gram-negative Bacterial Infections in Hospitalized Infants Under 3 Months

Registered drugNo placebo

Study on Cefiderocol for Treating Gram-negative Bacterial Infections in Hospitalized Infants Under 3 Months

Registered drugNo placebo

Bulgaria

Participants:0–17 years
Substances:Cefiderocol
Sponsor:Shionogi B.V.

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Factor VIII deficiency+1

Not yet recruiting

Study on Joint Health in Hemophilia A and B Patients Using Efmoroctocog Alfa or Eftrenonacog Alfa

Registered drugNo placebo

Study on Joint Health in Hemophilia A and B Patients Using Efmoroctocog Alfa or Eftrenonacog Alfa

Registered drugNo placebo

Bulgaria

Participants:0–17 years · 18–64 years · 65+ years
Substances:Efmoroctocog Alfa
Sponsor:Swedish Orphan Biovitrum AB (publ)

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Clinical research in Sofia

What the registry says about research in the country

01 Respiratory Research

Clinical studies focusing on respiratory infections and conditions, including trials for RSV, human metapneumovirus, and influenza vaccines in older adults. Research also includes investigations into asthma treatments and chronic rhinosinusitis management.

Respiratory Syncytial Virus (RSV)
Influenza Prevention
Chronic Rhinosinusitis
Asthma Management

02 Dermatological Studies

Comprehensive research into various skin conditions, evaluating new treatments for chronic urticaria, hidradenitis suppurativa, and different forms of psoriasis. These trials aim to improve patient outcomes through innovative therapeutic approaches.

Chronic Spontaneous Urticaria
Hidradenitis Suppurativa
Genital Psoriasis
Plaque Psoriasis

03 Autoimmune Disorders

Groundbreaking studies examining treatments for various autoimmune conditions, including multiple sclerosis, Sjögren's disease, and systemic sclerosis. Research focuses on developing targeted therapies to manage these chronic conditions.

Multiple Sclerosis
Sjögren's Disease
Systemic Sclerosis
Psoriatic Arthritis

04 Metabolic and Cardiovascular Research

Studies investigating treatments for metabolic disorders and heart conditions, including research on hypertriglyceridemia, obesity management, and heart failure prevention. Focus on both therapeutic interventions and preventive measures.

Hypertriglyceridemia
Obesity Management
Heart Failure Prevention
Cardiovascular Health

05 Oncology Research

Advanced clinical trials focusing on breast cancer treatments and blood disorders, particularly investigating new therapeutic approaches for advanced/metastatic breast cancer and myelodysplastic syndrome.

Advanced Breast Cancer
Myelodysplastic Syndrome
Targeted Therapies

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