Clinical trials in Sofia – page 55

772 clinical trials in Sofia, Bulgaria across 17 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Sofia at a glance

772

clinical trials

Research sites17

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772 trials in Sofia

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Myelofibrosis+1

Not recruiting

Study on the Safety and Effects of Navitoclax and Ruxolitinib for Patients with Myelofibrosis and Myeloproliferative Neoplasms

Registered drugNo placebo

Study on the Safety and Effects of Navitoclax and Ruxolitinib for Patients with Myelofibrosis and Myeloproliferative Neoplasms

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Celecoxib
Sponsor:AbbVie Deutschland GmbH & Co. KG

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Gastrointestinal melanoma+7

Not recruiting

Study of Encorafenib, Binimetinib, and Pembrolizumab for Patients with Advanced Melanoma with BRAF V600E/K Mutation

Registered drug

Study of Encorafenib, Binimetinib, and Pembrolizumab for Patients with Advanced Melanoma with BRAF V600E/K Mutation

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Binimetinib
Sponsor:Pfizer Inc.

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Heart failure with preserved ejection fraction

Not recruiting

Study on the Safety and Effectiveness of Tovinontrine for Adults with Chronic Heart Failure with Preserved Ejection Fraction

Investigational

Study on the Safety and Effectiveness of Tovinontrine for Adults with Chronic Heart Failure with Preserved Ejection Fraction

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Tovinontrine
Sponsor:Cardurion Pharmaceuticals Inc.

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Chronic cutaneous lupus erythematosus

Not recruiting

Study of daxdilimab injection for adults with moderate to severe discoid lupus erythematosus

Investigational

Study of daxdilimab injection for adults with moderate to severe discoid lupus erythematosus

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Daxdilimab
Sponsor:Horizon Therapeutics Ireland Designated Activity Company

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Dementia Alzheimer's type

Not recruiting

Study of ACP-204 for Treating Psychosis in Adults with Alzheimer's Disease

Investigational

Study of ACP-204 for Treating Psychosis in Adults with Alzheimer's Disease

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:ACP-204 tartrate
Sponsor:Acadia Pharmaceuticals Inc.

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Hidradenitis

Not recruiting

Study on Long-Term Use of Spesolimab for Patients with Hidradenitis Suppurativa Who Completed a Previous Spesolimab Study

Investigational

Study on Long-Term Use of Spesolimab for Patients with Hidradenitis Suppurativa Who Completed a Previous Spesolimab Study

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Spesolimab
Sponsor:Boehringer Ingelheim Espana S.A.

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Small cell lung cancer limited stage

Not recruiting

Study of Tarlatamab for Patients with Limited-Stage Small-Cell Lung Cancer After Chemoradiotherapy

Registered drug

Study of Tarlatamab for Patients with Limited-Stage Small-Cell Lung Cancer After Chemoradiotherapy

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Argipressin
Sponsor:Amgen Inc.

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Non-small cell lung cancer

Not recruiting

Study of Datopotamab Deruxtecan, Durvalumab, and Carboplatin for Advanced Non-Small Cell Lung Cancer in Patients Without Actionable Genomic Alterations

Registered drugNo placebo

Study of Datopotamab Deruxtecan, Durvalumab, and Carboplatin for Advanced Non-Small Cell Lung Cancer in Patients Without Actionable Genomic Alterations

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:AstraZeneca AB

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Cholangiocarcinoma

Not recruiting

Study of Durvalumab with Gemcitabine and Cisplatin for Patients with Advanced Biliary Tract Cancer

Registered drugNo placebo

Study of Durvalumab with Gemcitabine and Cisplatin for Patients with Advanced Biliary Tract Cancer

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Cisplatin
Sponsor:AstraZeneca AB

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Breast cancer+1

Not recruiting

Study of PF-07220060 and PF-07104091 with Endocrine Therapy for Patients with Advanced HR-positive HER2-negative Breast Cancer

Registered drugNo placebo

Study of PF-07220060 and PF-07104091 with Endocrine Therapy for Patients with Advanced HR-positive HER2-negative Breast Cancer

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Fulvestrant
Sponsor:Pfizer Inc.

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Dermatitis atopic

Not recruiting

Study on the Effectiveness and Safety of Amlitelimab for Patients Aged 12 and Older with Moderate-to-Severe Atopic Dermatitis Using Topical Corticosteroids

Registered drug

Study on the Effectiveness and Safety of Amlitelimab for Patients Aged 12 and Older with Moderate-to-Severe Atopic Dermatitis Using Topical Corticosteroids

Registered drug

Bulgaria

Participants:0–17 years · 18–64 years · 65+ years
Substances:Amlitelimab
Sponsor:Sanofi-Aventis Recherche & Developpement

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Systemic lupus erythematosus+3

Not recruiting

Study of Enpatoran in Adults with Systemic Lupus Erythematosus (SLE) and Cutaneous Lupus Erythematosus (CLE)

Investigational

Study of Enpatoran in Adults with Systemic Lupus Erythematosus (SLE) and Cutaneous Lupus Erythematosus (CLE)

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Enpatoran
Sponsor:Merck Healthcare KGaA

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Clinical research in Sofia

What the registry says about research in the country

01 Respiratory Research

Clinical studies focusing on respiratory infections and conditions, including trials for RSV, human metapneumovirus, and influenza vaccines in older adults. Research also includes investigations into asthma treatments and chronic rhinosinusitis management.

Respiratory Syncytial Virus (RSV)
Influenza Prevention
Chronic Rhinosinusitis
Asthma Management

02 Dermatological Studies

Comprehensive research into various skin conditions, evaluating new treatments for chronic urticaria, hidradenitis suppurativa, and different forms of psoriasis. These trials aim to improve patient outcomes through innovative therapeutic approaches.

Chronic Spontaneous Urticaria
Hidradenitis Suppurativa
Genital Psoriasis
Plaque Psoriasis

03 Autoimmune Disorders

Groundbreaking studies examining treatments for various autoimmune conditions, including multiple sclerosis, Sjögren's disease, and systemic sclerosis. Research focuses on developing targeted therapies to manage these chronic conditions.

Multiple Sclerosis
Sjögren's Disease
Systemic Sclerosis
Psoriatic Arthritis

04 Metabolic and Cardiovascular Research

Studies investigating treatments for metabolic disorders and heart conditions, including research on hypertriglyceridemia, obesity management, and heart failure prevention. Focus on both therapeutic interventions and preventive measures.

Hypertriglyceridemia
Obesity Management
Heart Failure Prevention
Cardiovascular Health

05 Oncology Research

Advanced clinical trials focusing on breast cancer treatments and blood disorders, particularly investigating new therapeutic approaches for advanced/metastatic breast cancer and myelodysplastic syndrome.

Advanced Breast Cancer
Myelodysplastic Syndrome
Targeted Therapies

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