Study of datopotamab deruxtecan with or without durvalumab compared to standard treatment for patients with Stage I-III triple-negative breast cancer who have remaining cancer after initial therapy

Registered drugNo placebo

Study of datopotamab deruxtecan with or without durvalumab compared to standard treatment for patients with Stage I-III triple-negative breast cancer who have remaining cancer after initial therapy

Registered drugNo placebo

Sweden

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:AstraZeneca AB

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Clinical research in Sundsvall

What the registry says about research in the country

01 Oncology Research

Innovative trials focusing on breast cancer treatment strategies, including studies for HER2-positive, triple-negative, and hormone receptor-positive variants. Additional research encompasses testicular cancer and prostate cancer therapies.

Advanced/Metastatic Breast Cancer
Testicular Cancer Management
Prostate Cancer Biomarkers

Several trials are evaluating novel drug combinations and personalized treatment approaches.

02 Cardiovascular Studies

Research focusing on acute ischemic stroke treatment and prevention strategies. Studies include evaluation of new therapies for heart failure and investigation of anticoagulation in special populations.

Stroke Treatment Innovation
Heart Failure Management
Thromboembolism Prevention

Trials are exploring both established and novel therapeutic approaches.

03 Public Health Initiatives

Comprehensive studies addressing obesity management in different age groups and HPV prevention strategies. Research includes innovative approaches to weight management in adolescents.

Pediatric Weight Management
HPV Vaccination Programs
Preventive Healthcare

Focus on population-level interventions and preventive strategies.

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Clinical trials in Sundsvall – page 2

35 trials in Sundsvall

Hormone-refractory prostate cancer+2

Study on the Effectiveness of Abiraterone, Capivasertib, and Enzalutamide in Patients with Metastatic Prostate Cancer

Induced labour+1

Study on Misoprostol for Inducing Labor in Pregnant Women: Comparing Outpatient and Inpatient Settings

Atrial fibrillation+2

Study on Apixaban for Preventing Stroke in Patients with Atrial Fibrillation and Stage 5 Chronic Kidney Disease

HER2 positive breast cancer

Study Comparing Trastuzumab Deruxtecan with Standard Treatment for Patients with HER2-positive Breast Cancer

Cerebrovascular accident

Study on Tranexamic Acid and Sodium Chloride for Patients with Stroke-Related Brain Bleeding

Malignant melanoma

Study on Short vs. Long Immunotherapy with Pembrolizumab and Nivolumab for Patients with High-Risk Skin Melanoma After Surgery

Urinary tract infection+1

Study of Pivmecillinam and Amoxicillin/Clavulanic Acid for Treating Urinary Tract Infections in Patients with Multidrug-Resistant Bacteria

Prophylaxis of nausea and vomiting

Study of palonosetron and fosaprepitant to prevent nausea and vomiting after laparoscopic surgery

Colorectal cancer

Study on Acetylsalicylic Acid for Colorectal Cancer Patients with PI3K Pathway Mutations

Ischaemic stroke

Study on Imatinib for Improving Recovery in Patients with Acute Ischemic Stroke

Chronic kidney disease

Study of BI 690517 and empagliflozin combination for protection of heart and kidneys in patients with chronic kidney disease

Triple negative breast cancer

Study of datopotamab deruxtecan with or without durvalumab compared to standard treatment for patients with Stage I-III triple-negative breast cancer who have remaining cancer after initial therapy

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