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Therapeutic area

Musculoskeletal and connective tissue disorders – page 8

  • 872 clinical trials
  • 359 recruiting
  • 331 conditions
  • 28 countries

Conditions in this area

331 conditions with trials, the busiest first

Clinical trials in Musculoskeletal and connective tissue disorders

872 trials across Europe, recruiting first

Type of trial
Recruitment status
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872 clinical trials

Osteoarthritis

Recruiting

A study comparing montelukast to placebo for reducing pain in patients with erosive osteoarthritis of the hands

Investigational
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Montelukast
  • Sponsor:Farmalider S.A.

A Study of Tulisokibart for Adults with Radiographic Axial Spondyloarthritis (Ankylosing Spondylitis)

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Tulisokibart
  • Sponsor:Merck Sharp & Dohme LLC

Still's disease

Recruiting

A Study of MAS825 in Children and Adults with Still's Disease to Test How Well It Works and How Safe It Is

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Human Igg1 Monoclonal Antibody Against Human Il-1 Beta And Human Il-18
  • Sponsor:Novartis Pharma AG

Osteoarthritis

Recruiting

Study of Methotrexate Treatment for Patients with Erosive Hand Osteoarthritis Not Responding to Standard Therapy

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Folic Acid
  • Sponsor:Centre Hospitalier Universitaire De Nice

Arthralgia

Recruiting

Study of Platelet-Rich Plasma Injections Combined with Exercise Compared to Betamethasone and Ropivacaine for Chronic Shoulder Pain Treatment

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Platelet Concentrate
  • Sponsor:Asociacion Instituto De Investigacion Sanitaria Biobizkaia

Study of Apitegromab Treatment in Children Under 2 Years Old with Spinal Muscular Atrophy (SMA)

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Apitegromab
  • Sponsor:Scholar Rock Inc.

Study of alpelisib in children and adults with PIK3CA-Related Overgrowth Spectrum (PROS)

InvestigationalNo placebo
Countries:AustriaAustria
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Alpelisib
  • Sponsor:Novartis Pharma AG

Comparison of Pregabalin and Baclofen Treatment in Patients with Spastic Motor Behavior Following Cervical or Thoracic Spinal Cord Injury

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Baclofen
  • Sponsor:Fakultni Nemocnice V Motole

Study of Vosoritide Safety and Effectiveness in Infants and Young Children (0 to 36 months) with Hypochondroplasia

Registered drug
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Vosoritide
  • Sponsor:Biomarin Pharmaceutical Inc.

Study of IMVT-1402 in Adults with Mild to Severe Generalized Myasthenia Gravis

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Imeroprubart
  • Sponsor:Immunovant Sciences GmbH

Back pain

Recruiting

Study comparing diclofenac, orphenadrine and paracetamol combination versus diclofenac alone and orphenadrine-paracetamol combination in patients with acute low back pain

Registered drug
Countries:GreeceGreece
  • Participants:18–64 years
  • Substances:Diclofenac potassium
  • Sponsor:Verisfield Single Member S.A.

Desmoid tumour

Recruiting

Study of nirogacestat in adult premenopausal women with desmoid tumors and aggressive fibromatosis to evaluate ovarian function recovery

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years
  • Substances:Nirogacestat Hydrobromide
  • Sponsor:Springworks Therapeutics Inc.

Substances studied in this area

The therapies tested most often in Musculoskeletal and connective tissue disorders trials.

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