Rare diseases
Investigational molecules
Locations
Study of Benralizumab Safety, Pharmacokinetics, and Efficacy in Children with Eosinophilic Disease
FrancePhase IIb Open‑Label Study of Intrathecal Melpida (AAV9/AP4M1) in Patients with Hereditary Spastic Paraplegia Type 50 (SPG50)
DenmarkWeekly Somatrogon versus Daily Somatropin in Children with Small for Gestational Age or Idiopathic Short Stature
CzechiaLong‑Term Safety Follow‑up of Ornithine Transcarbamylase Deficiency Patients Treated with ECUR‑506D and ECUR‑506A
FranceLong‑term immunity after a 6‑month‑old MMR vaccine (live attenuated) in infants: follow‑up of antibody levels 1‑3 years after routine vaccination
DenmarkEfficacy and safety of indacaterol acetate (combined with glycopyrronium bromide and mometasone furoate) versus salmeterol/fluticasone in adolescents with asthma
FranceLong‑Term Safety and Tolerability of KarXT in Adolescents with Schizophrenia and of KarXT + KarX‑EC in Children and Adolescents with Autism‑Related Irritability
RomaniaSafety and Efficacy of Ifinatamab Deruxtecan in Pediatric Patients Under 18 With Relapsed or Refractory Solid Tumors
BelgiumSafety and Efficacy of Sodium Phenylbutyrate Eye Drops in Children with Myopia
AustriaDuchenne Muscular Dystrophy in Patients with Gene Mutations Amenable to Exon 44 Skipping Treated with Delpacibart Zotadirsen
BelgiumAsciminib in Pediatric Patients With Philadelphia Positive Chronic Myeloid Leukemia in Chronic Phase
FranceLerodalcibep for Heterozygous Familial Hypercholesterolemia in Children and Adolescents 6 to 17 Years Old
NorwayClinical research plays a vital role in developing safe and effective treatments for younger patients. Pediatric clinical trials are trials designed specifically for infants, children, and adolescents. They help researchers understand how new therapies, vaccines, or medical procedures work in younger populations and ensure that treatments are safe and appropriate for their age group.
Children are not simply smaller versions of adults. Their bodies grow and develop, which means medications may work differently than they do in adults. For this reason, therapies must be carefully studied in pediatric populations.
Another important reason for pediatric clinical trials is that some diseases occur primarily or exclusively in children. Certain genetic conditions, developmental disorders, and rare pediatric diseases affect only young patients. Without dedicated research involving children and adolescents, it would be difficult to develop treatments specifically designed for these conditions.
Pediatric research also helps doctors determine:
Participants in pediatric clinical trials may include infants, children, and teenagers depending on the trial design. Each trial has specific eligibility criteria based on age, health condition, and medical history.
Because participants are minors, the process always involves:
This ensures that families fully understand the purpose of the research, the procedures involved, and any potential risks or benefits.
Safety is the highest priority in pediatric clinical trials. These trials follow strict ethical and regulatory standards in Europe and internationally. Research protocols are reviewed by ethics committees and regulatory authorities to ensure that the risks are minimized and justified by the potential benefits of the research.
Children participating in clinical trials are monitored closely by qualified healthcare professionals throughout the entire process. Families receive detailed information about trial procedures, medical monitoring, and the right to withdraw from the trial at any time.
Our search platform allows parents and guardians to explore pediatric clinical trials available in different regions. Using the search tool, families can find trials based on factors such as age group, medical condition, and location.
Clinical trials for children and adolescents are essential for advancing pediatric medicine. By participating in research, families contribute to the development of safer and more effective treatments for young patients today and in the future.
Tell us about your condition – we search every trial in Europe and connect you with the right site.
