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Centre Hospitalier De Roubaix

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France 11 Boulevard Lacordaire, Hopital Victor Provo, 59100 Roubaix, France

  • 12 trials recruiting
  • Acute myeloid leukaemia · Crohn's disease · Acute lymphocytic leukaemia
  • Adults and children

About Specializations

Centre Hospitalier De Roubaix in Roubaix, France specialises in clinical trials of conditions such as Acute myeloid leukaemia, Crohn's disease, Acute lymphocytic leukaemia, Asthma, and other specialisations. This site conducts important research.

Main research areas of the site

Peripheral T-cell Lymphoma

The medical center is at the forefront of research in Peripheral T-cell lymphoma (PTCL), focusing on innovative treatment strategies to improve patient outcomes. The center's research is particularly centered on the efficacy of autologous stem cell transplantation (ASCT) in prolonging progression-free survival for patients who achieve a complete response after induction chemotherapy.

  • Autologous Stem Cell Transplantation
  • Progression-Free Survival
  • Response Criteria for Lymphoma

Through these studies, the center aims to refine therapeutic approaches and establish new standards of care for PTCL patients.

Alzheimer's Disease

In the realm of Alzheimer's disease, the center is pioneering research into cognitive therapies, with a particular focus on the potential benefits of caffeine treatment. This research evaluates the impact of caffeine on cognitive decline in early to moderate stages of Alzheimer's, offering new insights into non-traditional therapeutic options.

  • Cognitive Decline
  • Non-Traditional Therapies
  • Early to Moderate Alzheimer's

The center's work in this area is crucial for developing alternative treatment pathways that could enhance the quality of life for Alzheimer's patients.

Mycobacterium Avium Complex Pulmonary Infections

The center is advancing the treatment of Mycobacterium avium complex (MAC) lung disease through comparative studies of antibiotic regimens. The research focuses on the non-inferiority of azithromycin compared to clarithromycin, providing clinicians with evidence-based options for effective treatment.

  • Antibiotic Regimens
  • Sputum Conversion Rate
  • Non-Inferiority Studies

This research is instrumental in guiding clinical decisions and optimizing treatment protocols for MAC infections.

Severe Allergic Asthma

In the field of severe allergic asthma, the center is exploring the management of asthma through the strategic withdrawal of omalizumab. The research aims to demonstrate the non-inferiority of discontinuing omalizumab in patients who have achieved asthma control, potentially reducing long-term medication dependency.

  • Omalizumab Withdrawal
  • Asthma Control
  • Medication Dependency

This study is pivotal in shaping future asthma management strategies, emphasizing patient-centered care.

Crohn's Disease

The center is conducting significant research in Crohn's Disease, focusing on the comparative efficacy of azathioprine and methotrexate when used in combination with adalimumab. This research aims to determine the optimal combination therapy for achieving endoscopic response in Crohn's patients.

  • Combination Therapy
  • Endoscopic Response
  • Azathioprine vs. Methotrexate

The findings from this research are expected to enhance therapeutic strategies and improve patient outcomes in Crohn's Disease management.

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Site location
11 Boulevard Lacordaire, Hopital Victor Provo59100 RoubaixFrance
Recruiting now
12 trials
Conditions studied
20
Partner status
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Ongoing trials

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17 clinical trials

Crohn's disease

Recruiting

One-Year Effectiveness Study of Guselkumab in Adults with Crohn’s Disease

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Guselkumab
  • Sponsor:Groupe D'etude Therapeutique Des Affections Inflammatoires Du Tube Digestif

Study of ziftomenib with drug combinations for adults with newly diagnosed acute myeloid leukemia with NPM1 or KMT2A genetic changes

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Kura Oncology Inc.

Polycythaemia vera+4

Recruiting

Study on Apixaban, Rivaroxaban, and Aspirin for Preventing Blood Clots in Patients with JAK2V617F-Positive Myeloproliferative Neoplasms

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Acetylsalicylic Acid
  • Sponsor:Centre Hospitalier Regional Et Universitaire De Brest

Crohn's disease

Recruiting

Study Comparing Azathioprine and Methotrexate with Adalimumab for Patients with Crohn's Disease

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Adalimumab
  • Sponsor:Centre Hospitalier Universitaire Amiens Picardie

Asthma

Recruiting

Study on Stopping Omalizumab in Patients with Well-Controlled Severe Allergic Asthma After 3 Years of Treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Omalizumab
  • Sponsor:Assistance Publique Hopitaux De Paris

Study Comparing Clarithromycin and Azithromycin for Treating Mycobacterium Avium Complex Lung Infections in Adults

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Azithromycin
  • Sponsor:Centre Hospitalier Universitaire Amiens Picardie

Study on the Effects of Caffeine on Cognitive Function in Patients with Early to Moderate Alzheimer's Disease

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Caffeine
  • Sponsor:Centre Hospitalier Universitaire De Lille

Study Comparing CPX-351 and Chemotherapy for Patients with New Intermediate or High-Risk Acute Myeloid Leukemia

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Cytarabine
  • Sponsor:Centre Hospitalier Universitaire De Nice

Study on Blood Pressure Management with Amiloride Hydrochloride, Indapamide, and Furosemide for Patients with Uncontrolled Hypertension and Chronic Kidney Disease

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Furosemide
  • Sponsor:Centre Hospitalier Regional Universitaire De Tours

Study on the Benefits of Autologous Stem Cell Transplantation for Patients with Peripheral T-cell Lymphoma Using Etoposide and Drug Combination

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Brentuximab Vedotin
  • Sponsor:LYSARC

Septic shock

Recruiting

Study on Landiolol Hydrochloride and Sodium Chloride for Reducing Mortality in Patients with Septic Shock and High Heart Rate

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Centre Hospitalier Universitaire Amiens Picardie

Study on Blinatumomab, Ponatinib, and Isatuximab for Adults Aged 18-65 with Newly Diagnosed Acute Lymphoblastic Leukemia or T-Cell Lymphoblastic Lymphoma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Blinatumomab
  • Sponsor:Assistance Publique Hopitaux De Paris
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