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Centre Hospitalier Metropole Savoie

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France Place Lucien Biset, Bp 31125, 73000 Chambery, France

  • 26 trials recruiting
  • Follicular lymphoma · Hormone receptor positive HER2 negative breast cancer · Non-small cell lung cancer
  • Adults and children

About Specializations

Centre Hospitalier Metropole Savoie in Chambery, France specialises in clinical trials of conditions such as Follicular lymphoma, Hormone receptor positive HER2 negative breast cancer, Non-small cell lung cancer, Plasma cell myeloma, and other specialisations. This site conducts important research.

Main research areas of the site

Pneumology and Oncology Research at Centre Hospitalier Metropole Savoie

Clinical research here focuses strongly on neoplasms, with studies centered on small cell lung cancer and prostate cancer. The trials are designed to evaluate new treatment combinations and compare how well they control advanced disease, especially in patients with limited treatment options.

  • Testing whether new cancer therapies can improve outcomes in extensive-stage small cell lung cancer
  • Assessing treatment effectiveness for metastatic prostate cancer in patients with reduced functional ability
  • Exploring better ways to manage advanced solid tumors through combination approaches

This work reflects a clear interest in improving both disease control and patient benefit in difficult-to-treat oncology settings.

Hematology and Lymphoma Studies

A major part of the site’s trial activity is dedicated to hemic and lymphatic diseases, especially follicular lymphoma, marginal zone lymphoma, acute myeloid leukemia, and myelodysplastic syndrome. These studies aim to improve treatment response, safety, and long-term disease control in blood cancers.

  • Evaluating new options for relapsed or refractory follicular lymphoma and marginal zone lymphoma
  • Studying treatment strategies for newly diagnosed acute myeloid leukemia and myelodysplastic syndrome
  • Comparing newer therapies with established lymphoma and leukemia treatment approaches

The Centre Hospitalier Metropole Savoie contributes to research that seeks more effective and better-tolerated care for patients with complex hematologic cancers.

Hemophilia and Joint Health Research

Another important area of study involves hemophilia A and hemophilia B, with attention to how preventive treatment supports joint health over time. The research is aimed at improving disease monitoring and understanding the impact of ongoing prophylaxis in patients living with bleeding disorders.

  • Assessing joint status in patients receiving preventive therapy for hemophilia
  • Using ultrasound to better understand musculoskeletal outcomes in long-term care
  • Supporting improved follow-up for people with inherited bleeding disorders

These studies combine hematology and diagnostic care, with the goal of making treatment follow-up more informative and patient-centered.

Targeted and Combination Therapy Development

The site is also involved in trials that test how newer targeted therapies perform when combined with standard treatments. These studies span lymphoma, leukemia, and other blood cancers, with a focus on safety, tolerability, and improved disease control.

  • Studying whether new combinations can improve outcomes in follicular lymphoma
  • Evaluating treatment response in indolent lymphoma and related subtypes
  • Comparing novel approaches with established regimens to find more effective care

This research highlights a broader effort in clinical oncology to refine treatment strategies and expand options for patients with relapsed or newly diagnosed disease.

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Site location
Place Lucien Biset, Bp 3112573000 ChamberyFrance
Recruiting now
26 trials
Conditions studied
59
Partner status
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65 clinical trials

Study of personalized treatment using drug combination therapy for young women with early stage hormone receptor-positive breast cancer based on gene expression testing

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Study of vicadrostat and empagliflozin combination in patients with type 2 diabetes, high blood pressure and cardiovascular disease

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:BI 690517
  • Sponsor:Boehringer Ingelheim Espana S.A.

Comparing sotorasib and pembrolizumab with chemotherapy for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Amgen Inc.

Study of ribociclib with or without chemotherapy for patients with hormone receptor positive, HER2 negative early breast cancer at intermediate risk

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Unicancer

A Study of MK-1084 and Drug Combination Versus Pembrolizumab and Chemotherapy for Adults with Advanced Lung Cancer with KRAS G12C Mutation

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Merck Sharp & Dohme LLC

Bronchiolitis+1

Recruiting

Study of nirsevimab and RSV vaccine (Abrysvo) for prevention of respiratory syncytial virus infection in infants during their first year of life

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years
  • Substances:Nirsevimab
  • Sponsor:Centre Hospitalier Annecy Genevois

Comparing rifampin-free treatment versus rifampin in adults with staphylococcal prosthetic valve endocarditis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Cefazolin Sodium
  • Sponsor:Centre Hospitalier Universitaire De Nantes
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Infliximab
  • Sponsor:AstraZeneca AB

Study of elranatamab and lenalidomide combination versus standard chemotherapy and transplant in newly diagnosed multiple myeloma patients

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bortezomib
  • Sponsor:Intergroupe Francophone Du Myelome

Study on the Effectiveness of Cemiplimab, Carboplatin, and Paclitaxel for Unfit or Elderly Patients with Unresectable Stage III Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Intergroupe Francophone De Cancerologie Thoracique

Pyrexia+1

Recruiting

Study on the Safety and Immune Response of the 20-Valent Pneumococcal Vaccine in Adults with Fever and High Risk for Pneumococcal Infection

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Pneumococcal Polysaccharide Serotype 1 Conjugated To Crm197 Adsorbed On Aluminium Phosphate
  • Sponsor:Centre Hospitalier Universitaire De Saint Etienne

Study Comparing Continuous and Fixed Duration Therapy with Daratumumab, Lenalidomide, and Dexamethasone for Patients with Relapsed Multiple Myeloma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Daratumumab
  • Sponsor:Assistance Publique Hopitaux De Paris
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