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Centre Jean Perrin

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France 58 Rue Montalembert, 63000 Clermont Ferrand, France

  • 87 trials recruiting
  • Breast cancer · Hormone-refractory prostate cancer · Triple negative breast cancer
  • Adults and children

About Specializations

Centre Jean Perrin in Clermont Ferrand, France specialises in clinical trials of conditions such as Breast cancer, Hormone-refractory prostate cancer, Triple negative breast cancer, Hormone receptor positive HER2 negative breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Urothelial Cancer

The medical center is at the forefront of research in urothelial cancer, focusing on innovative treatments for metastatic or locally advanced unresectable urothelial cancer. The center's research aims to improve overall survival rates through novel therapeutic approaches.

  • Metastatic Urothelial Cancer
  • Advanced Unresectable Urothelial Cancer

By exploring new treatment paradigms, the center contributes significantly to the understanding and management of this challenging condition.

Breast Cancer

Specializing in breast cancer, the center conducts extensive research on ER-positive, HER2-negative breast cancer, particularly in patients with genetic mutations. The focus is on enhancing progression-free survival through targeted therapies.

  • ER-positive, HER2-negative Breast Cancer
  • BRCA Gene Mutations

The center's work in this area is pivotal in developing personalized treatment strategies for breast cancer patients.

Migraine Research

The center is pioneering research in the field of migraines with aura, investigating the efficacy of novel prophylactic treatments. This research aims to provide new insights into migraine management and prevention.

  • Migraine Aura Prophylaxis

Through innovative studies, the center is enhancing the understanding of migraine pathophysiology and treatment.

Prostate Cancer

Focusing on prostate cancer, the center is involved in cutting-edge research for castration-resistant prostate cancer and hormone-sensitive prostate cancer. The goal is to improve survival outcomes through advanced therapeutic strategies.

  • Castration-Resistant Prostate Cancer
  • Hormone-Sensitive Prostate Cancer

The center's research is instrumental in developing new treatment protocols for prostate cancer patients.

Endometrial and Ovarian Cancer

The center is advancing research in endometrial and ovarian cancer, focusing on innovative treatment combinations to improve patient outcomes. This includes exploring the efficacy of novel drug combinations in recurrent cases.

  • Metastatic Endometrial Cancer
  • Ovarian Carcinosarcoma

Through its research, the center is contributing to the development of more effective therapies for these cancers.

Thyroid Cancer

Specializing in thyroid cancer, the center is conducting research on RET-mutant medullary thyroid cancer. The focus is on comparing the efficacy of different kinase inhibitors to improve progression-free survival.

  • RET-Mutant Medullary Thyroid Cancer

The center's research efforts are crucial in advancing treatment options for thyroid cancer patients.

Neuroendocrine Tumors

The center is at the forefront of research in neuroendocrine tumors, particularly those of gastroenteric or pancreatic origin. The focus is on improving progression-free survival through targeted radioligand therapies.

  • Gastroenteric Neuroendocrine Tumors
  • Pancreatic Neuroendocrine Tumors

By exploring new therapeutic avenues, the center is enhancing the management of neuroendocrine tumors.

Soft Tissue Sarcoma

The center is engaged in research on soft tissue sarcoma, focusing on improving metastasis-free survival through innovative chemotherapy regimens. This research is vital for patients with high-risk sarcomas.

  • High-Risk Soft Tissue Sarcoma

The center's work is pivotal in developing new treatment strategies for sarcoma patients.

Lung Cancer

Specializing in lung cancer, the center is conducting research on non-small cell lung cancer and small cell lung cancer. The focus is on improving survival outcomes through novel immunotherapy and chemotherapy combinations.

  • Non-Small Cell Lung Cancer
  • Small Cell Lung Cancer

The center's research is instrumental in advancing treatment options for lung cancer patients.

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Site location
58 Rue Montalembert63000 Clermont FerrandFrance
Recruiting now
87 trials
Conditions studied
108
Partner status
Verified site

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Ongoing trials

Clinical trials currently enrolling participants at this site.

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195 clinical trials

Study of personalized treatment using drug combination therapy for young women with early stage hormone receptor-positive breast cancer based on gene expression testing

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Study on Long-term Safety of Nivolumab and Drug Combination for Cancer Patients from Previous BMS Trials

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Study on the Long-term Safety and Efficacy of Pembrolizumab and Lenvatinib for Patients with Advanced Tumors

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Favezelimab
  • Sponsor:Merck Sharp & Dohme LLC

Rinatabart Sesutecan with or without bevacizumab versus standard platinum‑based chemotherapy drug combination in patients with recurrent platinum‑sensitive ovarian cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Genmab A/S

Bladder cancer

Recruiting

Study of Enfortumab Vedotin and Pembrolizumab for Bladder Preservation in Patients with Muscle‑Invasive Bladder Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Enfortumab Vedotin
  • Sponsor:Astellas Pharma Global Development Inc.

Docetaxel and Apalutamide in Patients with Metastatic Hormone-Sensitive Prostate Cancer Who Did Not Have a Deep PSA Response After Initial Apalutamide Treatment

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Apalutamide

Ovarian cancer

Recruiting

A study of sacituzumab tirumotecan and bevacizumab in patients with newly diagnosed advanced ovarian cancer following first-line platinum-based chemotherapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Bevacizumab
  • Sponsor:Merck Sharp & Dohme LLC

Bladder cancer

Recruiting

A study of sacituzumab tirumotecan versus docetaxel, paclitaxel, or vinflunine for patients with pretreated advanced or metastatic bladder cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:Merck Sharp & Dohme LLC

Endometrial cancer+2

Recruiting

A study comparing Rinatabart Sesutecan to other treatments in patients with endometrial cancer who have previously received platinum-based chemotherapy and PD-L1 therapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Paclitaxel
  • Sponsor:Genmab A/S

A study of JNJ-78278343 and docetaxel compared to docetaxel and prednisone in patients with metastatic castration-resistant prostate cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Docetaxel
  • Sponsor:Janssen Cilag International

Study of AMO959, lutetium (177Lu) vipivotide tetraxetan, and a drug combination for adults with advanced prostate cancer.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone
  • Sponsor:Novartis Pharma AG

Phase 1b-2 Study of Elacestrant and Abemaciclib in Patients with Brain Metastases from ER-Positive, HER2-Negative Breast Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Abemaciclib
  • Sponsor:Stemline Therapeutics Inc.
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