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CHU Grenoble Alpes

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France Boulevard de la Chantourne, 38700 La Tronche, France

  • 23 trials recruiting
  • Acute lymphocytic leukaemia · Plasma cell myeloma · Arteriosclerosis
  • Adults and children

About Specializations

CHU Grenoble Alpes in La Tronche, France specialises in clinical trials of conditions such as Acute lymphocytic leukaemia, Plasma cell myeloma, Arteriosclerosis, Breast cancer, and other specialisations. This site conducts important research.

Main research areas of the site

Immune System Diseases

The CHU Grenoble Alpes pediatric oncology unit is conducting research on acute lymphoblastic leukemia in children and adolescents, testing new dosing schedules of pegaspargase to improve drug exposure and reduce side effects.

  • Optimizing induction therapy for standard‑risk ALL
  • Assessing fractionated pegaspargase regimens
  • Evaluating toxicity profiles in medium‑risk pediatric patients

With 177 investigators participating, the study aims to enhance survival rates and quality of life for young patients while providing valuable data on pharmacokinetics and tolerance.

Neoplasms

Researchers at CHU Grenoble Alpes are evaluating the combination of olomorasib with immune checkpoint inhibitors for KRAS G12C‑mutant non‑small cell lung cancer, seeking to boost treatment efficacy and monitor safety in patients with unresectable disease.

  • Targeted KRAS inhibition strategies
  • Combination with PD‑1/PD‑L1 blockade
  • Biomarker‑driven patient stratification

This multicenter, open‑label trial integrates detailed immunophenotypic profiling to identify which patients benefit most, aiming to expand therapeutic options for a challenging cancer subtype.

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Site location
Boulevard de la Chantourne38700 La TroncheFrance
Recruiting now
23 trials
Conditions studied
64
Partner status
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Ongoing trials

Clinical trials currently enrolling participants at this site.

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54 clinical trials

Study of Brenipatide (LY3537031) in Adults with Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:LY3537031
  • Sponsor:Eli Lilly & Co.

Osteosarcoma

Recruiting

Cabozantinib Maintenance Therapy vs Best Supportive Care in Osteosarcoma Patients in Complete Remission or with Residual Disease after First‑Line Chemotherapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Cabozantinib
  • Sponsor:Institut Gustave Roussy

Treatment Study of Arsenic Trioxide, Tretinoin, and Gemtuzumab Ozogamicin for Children and Adolescents with Acute Promyelocytic Leukemia

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Arsenic Trioxide
  • Sponsor:Associazione Italiana Ematologia Oncologia Pediatrica

A study comparing one month versus one year of aspirin and clopidogrel treatment in patients with chronic limb-threatening ischemia after below-the-knee vascular therapy.

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Clopidogrel
  • Sponsor:Fondation Hopital Saint Joseph

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Sponsor:Eli Lilly & Co.
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Adalimumab
  • Sponsor:Assistance Publique Hopitaux De Paris

A study comparing prasinezumab with placebo for people with early-stage Parkinson's disease

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Prasinezumab
  • Sponsor:F. Hoffmann-La Roche AG

Study of chemotherapy with blinatumomab and tyrosine kinase inhibitors in newly diagnosed children and young adults with Philadelphia chromosome positive B-cell acute lymphoblastic leukemia

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years
  • Substances:Blinatumomab
  • Sponsor:Universita Degli Studi Di Milano Bicocca

Study of ribociclib with or without chemotherapy for patients with hormone receptor positive, HER2 negative early breast cancer at intermediate risk

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Study on Anti-CD20 Therapy and Drug Combination for Patients with Relapsing-Remitting Multiple Sclerosis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Dimethyl Fumarate
  • Sponsor:Centre Hospitalier Universitaire De Montpellier

Study on Dexamethasone for Patients with Advanced Relapsed or Refractory Multiple Myeloma

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Dexamethasone
  • Sponsor:Assistance Publique Hopitaux De Paris

Study on Stopping Dimethyl Fumarate and Drug Combination in Patients Aged 55+ with Inactive Relapsing-Remitting Multiple Sclerosis

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Dimethyl Fumarate
  • Sponsor:Les Hopitaux Universitaires De Strasbourg
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