Instituto de Investigacion Sanitaria Fundacion para la Investigacion del Hospital Clinico de Valencia-INCLIVA

At Instituto de Investigacion Sanitaria Fundacion para la Investigacion del Hospital Clinico de Valencia-INCLIVA, research in this area focuses on therapeutic techniques and supportive care approaches for kidney disease and refractory heart failure. The trials are designed to better understand how treatments may improve fluid balance and sodium handling in patients with complex chronic conditions.

• Improving diuresis and natriuresis in chronic kidney disease
• Evaluating sodium removal through peritoneal dialysis
• Assessing treatment strategies for refractory heart failure

This work reflects a practical focus on optimizing everyday clinical management for patients who need better control of fluid overload and related symptoms.

The oncology research at this Valencia site includes studies in neoplasms, especially cancers with microsatellite instability-high or mismatch repair deficiency. These trials aim to test new treatment options and explore how targeted therapies may help patients with advanced solid tumors that are difficult to treat.

• Studying MSIhi and dMMR advanced solid tumors
• Exploring novel cancer therapy options alone or in combination
• Supporting treatment development for metastatic and unresectable cancer

The research is centered on improving outcomes for patients whose tumors carry specific DNA alterations and may respond differently to standard care.