Study of Trastuzumab Deruxtecan for Patients with Early Stage HER2-Positive Breast Cancer
- Substances:PaclitaxelPertuzumab+2
Ireland- Participants:18–64 years · 65+ years
- Substances:Paclitaxel
- Sponsor:Cancer Trials Ireland
Rare diseases
Investigational molecules
Locations

Rcsi House, 121 Saint Stephen's Green, D02 H903 Dublin, Ireland
Research activity includes early-stage HER2-positive breast cancer, hormone receptor-positive and HER2-negative breast cancer with low recurrence score, and node-positive breast cancer with 1-3 positive nodes. The funded trials focus on neoadjuvant therapy, endocrine therapy, and decisions about the role of chemotherapy in recurrence risk.
Clinical interest also extends to treatment selection guided by tumour biology and risk of relapse.
Cancer Trials Ireland runs clinical trials in conditions such as Prostate cancer, Squamous cell carcinoma, Breast cancer, Serous cystadenocarcinoma ovary, among others.
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