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Goethe University Frankfurt
Sponsor

Goethe University Frankfurt

Germany Theodor-Stern-Kai 7, 60590 Frankfurt, Germany

About the sponsor

Research activity includes acute lymphoblastic leukemia, with studies in Philadelphia chromosome-positive ALL, B-cell precursor ALL, and T-cell ALL. The portfolio also covers relapsed/refractory disease and molecular remission strategies.

  • Relapsed/refractory ALL
  • CD38-positive T-cell ALL
  • Ph-positive ALL

These studies reflect a focus on treatment-resistant blood cancers and precision-directed immunotherapy or targeted therapy combinations.

About Specializations

Goethe University Frankfurt runs clinical trials in conditions such as Post-acute COVID-19 syndrome, Acute lymphocytic leukaemia, COVID-19, Urinary tract infection, among others.

Recruiting now

Ongoing trials

Clinical trials run by this sponsor – those enrolling participants first.

Condition
Country
City
Type of trial
Recruitment status
Quick filters

15 clinical trials

Post-acute COVID-19 syndrome

Recruiting

Randomized trial of bupropion hydrochloride for fatigue in patients with long COVID (post‑COVID syndrome)

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bupropion Hydrochloride
  • Sponsor:Goethe University Frankfurt

Urinary tract infection

Recruiting

Study on Fecal Microbiota Transfer for Preventing Recurrent Urinary Tract Infections in Premenopausal Women Using Intestifix

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Ascorbic Acid
  • Sponsor:Goethe University Frankfurt

T-cell type acute leukaemia

Recruiting

Study on the Safety and Effectiveness of Isatuximab and Drug Combination for Adults with Relapsed or Refractory CD38 Positive T-cell Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bortezomib
  • Sponsor:Goethe University Frankfurt

Acute lymphocytic leukaemia

Recruiting

Study on Ponatinib and Imatinib for Adults with Philadelphia-Chromosome Positive Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Blinatumomab
  • Sponsor:Goethe University Frankfurt

B precursor type acute leukaemia

Not yet recruiting

Phase II study of autologous enriched T‑cell therapy expressing CD19 and CD22 CARs in Philadelphia‑negative B‑precursor ALL patients with measurable residual disease

InvestigationalNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Autologous Enriched T Cells Retrovirally Transduced To Express Two Chimeric Antigen Receptors Targeting Cd19 And Cd22
  • Sponsor:Goethe University Frankfurt

COVID-19

Not yet recruiting

Study of nirmatrelvir and remdesivir to achieve viral clearance in immunocompromised patients with persistent COVID-19

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Nirmatrelvir
  • Sponsor:Goethe University Frankfurt

Enterobacter infection

Not yet recruiting

Study on the Effectiveness of Intestifix, Colistin Sulfate, and Vancomycin for Patients with Infections from Multidrug-Resistant Enterobacteriaceae

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Colistin Sulfate
  • Sponsor:Goethe University Frankfurt

Cardiac failure chronic

Not yet recruiting

Study on the Effects of Colchicine on Blood Vessel Function in Patients with Chronic Heart Failure and CHIP Mutations

Registered drug
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Colchicine
  • Sponsor:Goethe University Frankfurt

Anal cancer stage II+1

Not recruiting

Study on Durvalumab with Radiochemotherapy for Patients with Locally-Advanced Anal Cancer

Registered drugNo placebo
Countries:AustriaAustria
  • Participants:18–64 years · 65+ years
  • Substances:Durvalumab
  • Sponsor:Goethe University Frankfurt

Rectal cancer

Not recruiting

Study Comparing Short Course Radiotherapy and Chemoradiotherapy with Fluorouracil, Calcium Folinate, and Capecitabine for Intermediate and High-Risk Rectal Cancer Patients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Goethe University Frankfurt

Acute lymphocytic leukaemia

Not recruiting

Study of Venetoclax and Blinatumomab for Adults with Relapsed or Refractory B Cell Precursor Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Blinatumomab
  • Sponsor:Goethe University Frankfurt

Post-acute COVID-19 syndrome

Not recruiting

Study on the Effects of Vidofludimus Calcium for Patients with Post-COVID Syndrome

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Vidofludimus Calcium
  • Sponsor:Goethe University Frankfurt

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