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Karolinska Institutet
Sponsor

Karolinska Institutet

Sweden Nobels Vag 6, 171 65 Solna, Sweden

About the sponsor

Clinical research includes heart failure with reduced ejection fraction, severe chronic kidney disease, acute myocardial infarction, and left ventricular thrombosis, with additional interest in treatment strategies for acute ischaemic stroke.

  • Heart failure
  • Chronic kidney disease
  • Myocardial infarction
  • Stroke
  • Thromboembolic disease

Work in this area also extends to anticoagulation, biomarker-informed treatment selection, and cardiovascular complications after major cardiac events.

About Specializations

Karolinska Institutet runs clinical trials in conditions such as Breast cancer female, Abortion induced, Rhinitis allergic, Colorectal cancer, among others.

Recruiting now

Ongoing trials

Clinical trials run by this sponsor – those enrolling participants first.

Condition
Country
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Type of trial
Recruitment status
Quick filters

25 clinical trials

Respiratory syncytial virus infection

Recruiting

Study of RSVPreF3 vaccine with AS01E adjuvant in adults aged 60-65 and over 80 years to prevent respiratory syncytial virus infection

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Respiratory Syncytial Virus, Glycoprotein F, Recombinant, Stabilised In The Pre-Fusion Conformation, Adjuvanted With As01E
  • Sponsor:Karolinska Institutet

Breast cancer female

Recruiting

Study of personalized tamoxifen dosing (10mg, 20mg, or 40mg daily) compared to standard dose (20mg) in women with breast cancer to improve treatment continuation

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Tamoxifen
  • Sponsor:Karolinska Institutet

Polycystic ovarian syndrome

Recruiting

Study on Acupuncture and Metformin for Improving Insulin Sensitivity in Women with Polycystic Ovary Syndrome

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · Healthy volunteers
  • Substances:Metformin Hydrochloride
  • Sponsor:Karolinska Institutet

Cardiac ventricular thrombosis+1

Recruiting

Study Comparing Apixaban and Warfarin for Patients with Heart Clots After a Heart Attack

Registered drugNo placebo
Countries:DenmarkDenmark
  • Participants:18–64 years · 65+ years
  • Substances:Apixaban
  • Sponsor:Karolinska Institutet

Bone loss

Recruiting

Study on the Effectiveness of Phenoxymethylpenicillin Potassium and Amoxicillin for Patients Needing Oral Bone Augmentation

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Amoxicillin
  • Sponsor:Karolinska Institutet

Rheumatoid arthritis

Recruiting

Study Comparing Conventional Therapy and Biologic Treatments for Early Rheumatoid Arthritis Using Hydroxychloroquine, Abatacept, and Azathioprine in Responsive Patients

Registered drugNo placebo
Countries:DenmarkDenmark
  • Participants:18–64 years · 65+ years
  • Substances:Abatacept
  • Sponsor:Karolinska Institutet

Pain in jaw

Recruiting

Study on the Effects of Botulinum Toxin in Patients with Jaw Muscle Pain (TMD)

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years
  • Sponsor:Karolinska Institutet

Hormone-refractory prostate cancer+2

Recruiting

Study on the Effectiveness of Abiraterone, Capivasertib, and Enzalutamide in Patients with Metastatic Prostate Cancer

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone
  • Sponsor:Karolinska Institutet

Ectopic pregnancy

Recruiting

Study on Mifepristone and Letrozole for Treating Ectopic Pregnancy in Comparison to Methotrexate

Registered drugNo placebo
Countries:DenmarkDenmark
  • Participants:18–64 years
  • Substances:Letrozole
  • Sponsor:Karolinska Institutet

Sedative therapy

Not yet recruiting

Patient‑controlled propofol versus alfentanil and midazolam sedation for adenoma patients undergoing diagnostic and therapeutic colonoscopy: a satisfaction study

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Midazolam
  • Sponsor:Karolinska Institutet

Abortion induced

Not yet recruiting

Ropivacaine hydrochloride versus electrolytes for pain relief in women undergoing second‑trimester medical abortion after 13 weeks

Registered drug
Countries:SwedenSweden
  • Participants:18–64 years
  • Substances:Mannitol
  • Sponsor:Karolinska Institutet

Chronic kidney disease

Not yet recruiting

Study of eplerenone in patients with heart failure and reduced ejection fraction who also have severe chronic kidney disease

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years · 65+ years
  • Substances:Altizide
  • Sponsor:Karolinska Institutet

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