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Leiden University Medical Center
Sponsor

Leiden University Medical Center

The Netherlands P. O. Box 9600, 2300 RC Leiden, The Netherlands

About the sponsor

Clinical research spans solid tumours and haematological malignancies, with a strong emphasis on breast cancer, colorectal cancer, gastric cancer, pancreatic cancer, rectal cancer, melanoma, ovarian carcinoma, endometrial cancer, and lymphoma. Imaging-guided surgery and tumour delineation are central themes, including fluorescence-based approaches in the operating room and whole-body staging.

  • Fluorescence-guided surgery
  • Intraoperative tumour detection
  • Colorectal and pancreatic malignancies
  • Melanoma and brain metastases

Research also includes biomarkers and imaging tools for surgical planning, residual disease assessment, and improved localisation of metastatic or recurrent lesions.

About Specializations

Leiden University Medical Center runs clinical trials in conditions such as Rectal cancer, Rheumatoid arthritis, Cluster headache, Systemic lupus erythematosus, among others.

Recruiting now

Ongoing trials

Clinical trials run by this sponsor – those enrolling participants first.

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Quick filters

61 clinical trials

Herpes zoster

Recruiting

Non‑inferiority of fractional varicella zoster virus glycoprotein E vaccine (AS01B) versus recombinant varicella zoster virus glycoprotein E vaccine in adults with shingles

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Recombinant Varicella Zoster Virus Glycoprotein E
  • Sponsor:Leiden University Medical Center

Ovarian cancer

Recruiting

Study of Tumor-Infiltrating Lymphocyte Cell Therapy and Aldesleukin for Patients with Advanced Stage Ovarian Cancer as Initial Treatment

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:TIL cells
  • Sponsor:Leiden University Medical Center

Calculus urinary

Recruiting

A Study Testing Erector Spinae Plane Block with Ropivacaine versus Placebo for Pain Relief in Adults with Acute Kidney Stone Pain in the Emergency Department

Registered drug
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Ropivacaine Hydrochloride
  • Sponsor:Leiden University Medical Center

Transplant rejection+1

Recruiting

A Study of Belimumab to Help Identify Safe Kidney Transplant Matches in Patients with High Antibody Levels Against Donor Tissue Types

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Belimumab
  • Sponsor:Leiden University Medical Center

Renal cell carcinoma

Recruiting

Testing Cabozantinib Dose Skipping Schedule Compared to Dose Reduction in Patients with Kidney Cancer Taking Cabozantinib Treatment

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Cabozantinib
  • Sponsor:Leiden University Medical Center

B-cell lymphoma+2

Recruiting

Study of LUMC-BOB1-B7-TCR.

InvestigationalNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:LUMC-BOB1-B7-TCR.1
  • Sponsor:Leiden University Medical Center

Asplenia

Recruiting

Study of Pneumococcal Vaccine Response in Patients Without a Spleen: Comparing Vaccination Before and After Spleen Removal Using PCV20 and PCV21

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Pneumococcal Polysaccharide Serotype 1 Conjugated To Crm197 Adsorbed On Aluminium Phosphate
  • Sponsor:Leiden University Medical Center

Malignant melanoma

Recruiting

Study to Evaluate IOpener-Melanoma Test for Predicting Response to Immunotherapy in Stage III or IV Skin Melanoma Patients

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Nivolumab
  • Sponsor:Leiden University Medical Center

Study on BCG Vaccine and Rabies Virus (Inactivated) for Healthy Volunteers: Exploring Pre-Vaccination Immune Status and Its Impact on Vaccine Response

Recruiting
Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:Mycobacterium bovis, Danish strain 1331
  • Sponsor:Leiden University Medical Center

HIV infection

Recruiting

Study of pneumococcal vaccines in healthy young adults, older adults and people with HIV infection

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years · Healthy volunteers
  • Substances:Pneumococcal polysaccharide serotype 1
  • Sponsor:Leiden University Medical Center

Rabies+1

Recruiting

Study of Single-Dose Rabies Vaccine (Inactivated Flury LEP Strain) Immunity After Five Years: Testing Booster Response in Previously Vaccinated Adults

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:Rabies virus (inactivated) strain Flury LEP
  • Sponsor:Leiden University Medical Center

Influenza immunisation

Recruiting

Study on Antibody Responses in Healthy Individuals After Intranasal and Intramuscular Influenza Vaccination with Fluenz Tetra and Vaxigrip Tetra

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · Healthy volunteers
  • Substances:A/DARWIN/9/2021 (H3N2) - LIKE STRAIN (A/NORWAY/16606/2021, MEDI 355293)
  • Sponsor:Leiden University Medical Center

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