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Ospedale Pediatrico Bambino Gesu
Sponsor

Ospedale Pediatrico Bambino Gesu

Italy Piazza Di Sant'onofrio 4, 00165 Rome, Italy

About the sponsor

Clinical research at Ospedale Pediatrico Bambino Gesu includes CAR T-cell therapy and related immuno-oncology approaches for children and young adults with relapsed/refractory acute lymphoblastic leukemia, B-cell non-Hodgkin lymphoma, neuroblastoma, and GD2-positive tumours.

  • CD19-directed CAR T cells
  • GD2-directed CAR T cells
  • Relapsed/refractory B-cell malignancies
  • Malignant central nervous system tumours

The oncology programme also extends to minimal residual disease assessment and response-focused treatment strategies in paediatric blood cancers and solid tumours.

About Specializations

Ospedale Pediatrico Bambino Gesu runs clinical trials in conditions such as Allogenic stem cell transplantation, Malignant central nervous system neoplasm, Cardiac failure acute, Dilated cardiomyopathy, among others.

Recruiting now

Ongoing trials

Clinical trials run by this sponsor – those enrolling participants first.

Condition
Country
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Type of trial
Recruitment status
Quick filters

10 clinical trials

Allogenic stem cell transplantation

Recruiting

Testing Stem Cell Transplant Methods and Medications Including Ruxolitinib and Blinatumomab for Children and Young Adults with Acute Lymphoblastic Leukemia

Registered drugNo placebo
Countries:AustriaAustria
  • Participants:0–17 years · 18–64 years
  • Substances:Blinatumomab
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Malignant central nervous system neoplasm

Recruiting

Study on the Safety of Anti-GD2 CAR T Cells, Cyclophosphamide, and Fludarabine in Children and Young Adults with Relapsed or Refractory Brain Tumors

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years
  • Substances:Cyclophosphamide
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Cardiac failure acute+1

Recruiting

Study on Early Use of Ivabradine for Children with Heart Failure Due to Dilated Cardiomyopathy

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:0–17 years
  • Substances:Ivabradine Hydrochloride
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Neuroblastoma

Recruiting

Study of GD2-CAR T Cells, Cyclophosphamide, and Fludarabine for Children with High-Risk or Relapsed Neuroblastoma and Other GD2+ Tumors

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years
  • Substances:Cyclophosphamide
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Dent's disease

Recruiting

Study on the Effectiveness and Safety of Alpelisib for Patients with Dent 2 Disease

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years
  • Substances:Alpelisib
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Trisomy 21

Recruiting

Study on Bumetanide for Improving Cognitive Function in Children and Adolescents with Down Syndrome

Registered drug
Countries:ItalyItaly
  • Participants:0–17 years
  • Substances:Bumetanide
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Neuromyelitis optica spectrum disorder+7

Not yet recruiting

Safety and dose‑finding study of CD19‑CART01 in patients with SLE, SSc, DM/PM, IMNM, AAV, MG, NMOSD, or chronic GVHD

InvestigationalNo placebo
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years · 65+ years
  • Sponsor:Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico

Acute HIV infection

Not recruiting

Study on HIV Treatment Interruption in Children with Perinatal HIV Using Lamivudine and Drug Combination

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years
  • Substances:Abacavir
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Acute lymphocytic leukaemia+2

Not recruiting

Study of CD19-CAR_Lenti, Fludarabine, and Cyclophosphamide in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia or Aggressive B-Cell Lymphomas

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:0–17 years · 18–64 years
  • Substances:Cyclophosphamide
  • Sponsor:Ospedale Pediatrico Bambino Gesu

Bipolar disorder

Not recruiting

Study on Memantine Hydrochloride for Adolescents with Bipolar Disorder

Registered drug
Countries:ItalyItaly
  • Participants:0–17 years
  • Substances:Memantine Hydrochloride
  • Sponsor:Ospedale Pediatrico Bambino Gesu

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