Clinical trials in Brest – page 7

591 clinical trials in Brest, France across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Brest at a glance

591

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591 trials in Brest

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Cervix carcinoma

Recruiting

A Study of Sacituzumab Tirumotecan, Pembrolizumab, and Bevacizumab for Patients with Metastatic Cervical Cancer That Has Spread or Returned

Registered drugNo placebo

A Study of Sacituzumab Tirumotecan, Pembrolizumab, and Bevacizumab for Patients with Metastatic Cervical Cancer That Has Spread or Returned

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:Merck Sharp & Dohme LLC

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Crohn's disease

Recruiting

A study testing how well mirikizumab works to achieve transmural healing in patients with Crohn's Disease

Registered drugNo placebo

A study testing how well mirikizumab works to achieve transmural healing in patients with Crohn's Disease

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Mirikizumab
Sponsor:Groupe D'etude Therapeutique Des Affections Inflammatoires Du Tube Digestif

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Non-small cell lung cancer

Recruiting

A Study Comparing PF-08046054 to Docetaxel in Adults with Previously Treated PD-L1 Positive Non-Small Cell Lung Cancer

Registered drugNo placebo

A Study Comparing PF-08046054 to Docetaxel in Adults with Previously Treated PD-L1 Positive Non-Small Cell Lung Cancer

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Docetaxel
Sponsor:Pfizer Inc.

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Hormone-refractory prostate cancer

Recruiting

A Study of JNJ-78278343 Compared to Placebo for Patients with Advanced Prostate Cancer That No Longer Responds to Hormone Treatment

Investigational

A Study of JNJ-78278343 Compared to Placebo for Patients with Advanced Prostate Cancer That No Longer Responds to Hormone Treatment

Investigational

France

Participants:18–64 years · 65+ years
Substances:JNJ-78278343
Sponsor:Janssen Cilag International

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Non-small cell lung cancer stage IV

Recruiting

A Study of Amivantamab and Lazertinib for Adults with EGFR-Mutated Advanced or Metastatic Non-Small Cell Lung Cancer

InvestigationalNo placebo

A Study of Amivantamab and Lazertinib for Adults with EGFR-Mutated Advanced or Metastatic Non-Small Cell Lung Cancer

InvestigationalNo placebo

France

Participants:18–64 years · 65+ years
Substances:Amivantamab
Sponsor:Janssen Cilag International

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Clear cell renal cell carcinoma

Recruiting

A Study Testing Casdatifan and Cabozantinib Compared to Placebo and Cabozantinib in Patients With Advanced Clear Cell Kidney Cancer

Registered drug

A Study Testing Casdatifan and Cabozantinib Compared to Placebo and Cabozantinib in Patients With Advanced Clear Cell Kidney Cancer

Registered drug

France

Participants:18–64 years · 65+ years
Substances:AB521
Sponsor:Arcus Biosciences Inc.

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Cutaneous lupus erythematosus

Recruiting

Comparing lenalidomide and methotrexate for patients with difficult-to-treat cutaneous lupus erythematosus

Registered drugNo placebo

Comparing lenalidomide and methotrexate for patients with difficult-to-treat cutaneous lupus erythematosus

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Lenalidomide
Sponsor:Assistance Publique Hopitaux De Paris

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Endometrial cancer+12

Recruiting

A Study of Zanidatamab for Patients with Previously Treated HER2-Expressing Solid Tumors

InvestigationalNo placebo

A Study of Zanidatamab for Patients with Previously Treated HER2-Expressing Solid Tumors

InvestigationalNo placebo

France

Participants:18–64 years · 65+ years
Substances:Zanidatamab
Sponsor:Jazz Pharmaceuticals Ireland Limited

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Adenocarcinoma gastric+2

Recruiting

A study comparing injection under the skin versus infusion into the vein of tislelizumab with chemotherapy for patients with advanced gastric or gastroesophageal junction cancer

Registered drugNo placebo

A study comparing injection under the skin versus infusion into the vein of tislelizumab with chemotherapy for patients with advanced gastric or gastroesophageal junction cancer

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Tislelizumab
Sponsor:BeOne Medicines AG

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Gastrooesophageal cancer+1

Recruiting

A study comparing trifluridine, tipiracil, and fruquintinib versus trifluridine and tipiracil alone for patients with metastatic stomach or esophageal cancer

Registered drugNo placebo

A study comparing trifluridine, tipiracil, and fruquintinib versus trifluridine and tipiracil alone for patients with metastatic stomach or esophageal cancer

Registered drugNo placebo

France

Participants:18–64 years · 65+ years
Substances:Fruquintinib
Sponsor:Fondation Franc.Cancerologie Digestive

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Non-small cell lung cancer stage IV+2

Recruiting

A Study of BMS-986504 with Drug Combination Compared to Placebo with Drug Combination in Patients with Advanced Non-Small Cell Lung Cancer Starting First Treatment

Registered drug

A Study of BMS-986504 with Drug Combination Compared to Placebo with Drug Combination in Patients with Advanced Non-Small Cell Lung Cancer Starting First Treatment

Registered drug

France

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Thrombocytopenia

Recruiting

Study of romiplostim given before heart surgery in patients with low platelet counts to improve blood clotting after surgery

Registered drug

Study of romiplostim given before heart surgery in patients with low platelet counts to improve blood clotting after surgery

Registered drug

France

Participants:18–64 years · 65+ years
Substances:Romiplostim
Sponsor:Centre Hospitalier Universitaire De Nantes

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Clinical research in Brest

What the registry says about research in the country

01 Oncology Research

Groundbreaking trials focusing on head and neck squamous cell carcinoma, exploring innovative treatments combining radiotherapy with targeted therapies. Studies also examine new approaches for esophageal cancer and pancreatic adenocarcinoma.

Advanced Cancer Therapies
Combination Treatments
Targeted Therapeutics

Multiple trials are investigating novel drug combinations and immunotherapy approaches for various cancer types.

02 Autoimmune Conditions

Comprehensive research into Sjögren's syndrome treatment options, including innovative biological therapies and histopathological studies. Additional focus on rheumatoid arthritis and novel therapeutic approaches.

Biological Treatments
Disease Mechanisms
Treatment Response

Studies aim to understand disease mechanisms and evaluate new therapeutic options for autoimmune disorders.

03 Cardiovascular and Respiratory Studies

Investigation of treatments for pulmonary arterial hypertension and heart failure prevention. Research includes innovative drug combinations and preventive approaches for cardiovascular conditions.

Heart Failure Prevention
Hypertension Management
Asthma Control

Focus on developing effective treatments for chronic cardiovascular and respiratory conditions.

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