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Clinical trials in Brno

394 clinical trials in Brno, Czechia across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Brno at a glance
394
clinical trials
  • Research sites1
Type of trial
Recruitment status
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394 trials in Brno

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Pancreatic carcinoma metastatic

Recruiting

Phase 3 Study of atebimetinib with gemcitabine and paclitaxel versus gemcitabine and paclitaxel in patients with metastatic pancreatic cancer

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Paclitaxel

Obesity+2

Recruiting

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years
  • Sponsor:Novo Nordisk A/S

A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis

Recruiting
Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years
  • Sponsor:Zenas Biopharma (USA) LLC

Colitis ulcerative

Recruiting

Long‑Term Safety and Efficacy of SPY001-001, SPY002 and SPY003 in Adults with Ulcerative Colitis

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:SPY002
  • Sponsor:Spyre Therapeutics Inc.

Primary progressive multiple sclerosis

Recruiting

Orelabrutinib in Patients with Primary Progressive Multiple Sclerosis

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years
  • Sponsor:Zenas Biopharma (USA) LLC

Crohn's disease

Recruiting

A study to evaluate the effectiveness and safety of duvakitug in patients with moderate to severe Crohn's disease

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Crohn's disease

Recruiting

A study to evaluate the efficacy and safety of duvakitug in patients with moderate to severe Crohn's disease

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Duvakitug
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Chronic inflammatory demyelinating polyradiculoneuropathy

Recruiting

A Study Comparing Empasiprubart Versus Intravenous Immunoglobulin in Adults With Chronic Inflammatory Demyelinating Polyneuropathy

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Empasiprubart
  • Sponsor:Argenx

Colitis ulcerative

Recruiting

A Study of Long-acting Antibodies SPY001-001 and SPY002 Alone and Combined for Adults with Moderate to Severe Ulcerative Colitis

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:SPY002
  • Sponsor:Spyre Therapeutics Inc.

Cachexia

Recruiting

A Study of Visugromab Compared to Placebo in Patients with Cancer-Related Cachexia to Test How Well It Works and How Safe It Is

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Visugromab
  • Sponsor:CatalYm GmbH

Cardiovascular disorder+1

Recruiting

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Zilebesiran
  • Sponsor:Alnylam Pharmaceuticals Inc.

Dementia Alzheimer's type

Recruiting

A study testing xanomeline tartrate and trospium chloride for treating agitation in patients with Alzheimer's disease

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Trospium Chloride
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Clinical research in Brno

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01 Oncology Research

Innovative clinical trials focusing on advanced cancer treatments, including studies for leukemia, prostate cancer, and gastric cancer.

  • Chronic Lymphocytic Leukemia
  • Metastatic Prostate Cancer
  • Esophageal Cancer
  • Advanced Breast Cancer

Studies evaluating novel therapeutic combinations and targeted treatments for various cancer types.

02 Autoimmune Conditions

Research focused on treating inflammatory disorders and autoimmune conditions, with particular emphasis on innovative therapies.

  • Ulcerative Colitis
  • Psoriatic Arthritis
  • Plaque Psoriasis
  • Multiple Sclerosis

Evaluating new biological treatments and their long-term effectiveness in managing chronic conditions.

03 Respiratory and Cardiovascular

Studies addressing respiratory diseases and heart conditions, focusing on prevention and treatment strategies.

  • Chronic Obstructive Pulmonary Disease
  • RSV Prevention
  • Heart Failure Prevention
  • Cardiovascular Risk Management

Testing innovative approaches to improve patient outcomes in respiratory and cardiac conditions.

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