Innovative research focusing on inflammatory bowel diseases, including studies evaluating new therapies for both ulcerative colitis and Crohn's disease. Clinical trials are investigating advanced treatments like OD-07656 and TAK-279 for managing moderate to severe cases.

Ulcerative Colitis Treatment
Crohn's Disease Management
Clostridioides difficile Studies

Additional research explores antibiotic optimization and novel therapeutic combinations.

02 Oncology Research

Comprehensive studies in cancer treatment, including trials for metastatic prostate cancer and advanced gastric cancers. Research focuses on innovative therapies combining targeted treatments with immunotherapy approaches.

Prostate Cancer Therapeutics
Gastric Cancer Treatment
Melanoma Interventions

Investigations include novel drug combinations and immunotherapy strategies.

03 Neurological Conditions

Advanced research in multiple sclerosis and Parkinson's disease, evaluating new therapeutic approaches and comparing treatment efficacies. Studies include assessments of innovative medications and comparative analyses.

Multiple Sclerosis Treatments
Parkinson's Disease Therapy
Stroke Management

Focus on both disease-modifying treatments and symptom management.

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Clinical trials in Hradec Kralove

191 trials in Hradec Kralove

Pancreatic carcinoma metastatic

Phase 3 Study of atebimetinib with gemcitabine and paclitaxel versus gemcitabine and paclitaxel in patients with metastatic pancreatic cancer

Study of JNJ-78934804 (guselkumab and golimumab) versus guselkumab in adults with moderately to severely active Crohn’s disease

Study of JNJ-78934804 (guselkumab and golimumab) versus guselkumab in adults with moderately to severely active Crohn’s disease

Type 2 diabetes mellitus

A study to assess the effect of elecoglipron alone and in combination with dapagliflozin on blood sugar control in adults with Type 2 diabetes

Chronic kidney disease

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Chronic obstructive pulmonary disease

Study of lunsekimig versus placebo in adults with inadequately controlled eosinophilic COPD

Colitis ulcerative

Study of LY4268989 adipic acid in adults with moderately to severely active ulcerative colitis

A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis

A Phase 3 Study of Orelabrutinib to Delay Disability Progression in Patients with Non‑Active Secondary Progressive Multiple Sclerosis

Primary progressive multiple sclerosis

Orelabrutinib in Patients with Primary Progressive Multiple Sclerosis

Bladder transitional cell carcinoma+1

A study of loxo-435, enfortumab vedotin, and pembrolizumab in adults with advanced or metastatic bladder cancer

Crohn's disease

A study to evaluate the effectiveness and safety of duvakitug in patients with moderate to severe Crohn's disease

Crohn's disease

A study to evaluate the efficacy and safety of duvakitug in patients with moderate to severe Crohn's disease

Hereditary angioedema with C1 esterase inhibitor deficiency+1

A study of navenibart for long-term safety in patients with hereditary angioedema

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