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Clinical trials in Coimbra – page 4

263 clinical trials in Coimbra, Portugal across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Coimbra at a glance
263
clinical trials
  • Research sites2
Type of trial
Recruitment status
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263 trials in Coimbra

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A study comparing prasinezumab with placebo for people with early-stage Parkinson's disease

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Prasinezumab
  • Sponsor:F. Hoffmann-La Roche AG

Study of Surabgene Lomparvovec Compared to Ranibizumab for Adults with Wet Age-Related Macular Degeneration

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Ranibizumab
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Testing MK-2870 with pembrolizumab compared to pembrolizumab alone after surgery in patients with non-small cell lung cancer who did not respond fully to treatment

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Merck Sharp & Dohme LLC

Mite allergy

Recruiting

A study testing dust mite allergy extracts from Dermatophagoides pteronyssinus and Dermatophagoides farinae for patients with allergic rhinoconjunctivitis with or without controlled asthma

Registered drug
Countries:PortugalPortugal
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:LETI Pharma S.L.U.

Study of Revumenib and Chemotherapy for Patients with Newly Diagnosed Acute Myeloid Leukemia with NPM1 Gene Mutation

Registered drug
Countries:PortugalPortugal
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Cytarabine
  • Sponsor:Syndax Pharmaceuticals Inc.

A study of RO7268489 added to ocrelizumab compared to placebo in adults with progressive multiple sclerosis

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years
  • Substances:Ocrelizumab
  • Sponsor:F. Hoffmann-La Roche AG

A Study of Amivantamab With Carboplatin and Pembrolizumab for Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Amivantamab
  • Sponsor:Janssen Cilag International

Study of KarXT (trospium chloride and xanomeline tartrate) and KarX-EC (xanomeline tartrate) for cognitive impairment in mild to moderate Alzheimer's disease

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Trospium Chloride
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Study of xanomeline tartrate and trospium chloride combination for treating agitation in Alzheimer's disease patients

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Trospium Chloride
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Breast cancer+1

Recruiting

Study of Izalontamab Brengitecan Compared to Standard Chemotherapy in Untreated Triple-negative or ER-low, HER2-negative Breast Cancer Patients Not Eligible for Anti-PD1/PD-L1 Treatment

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

Study comparing GSK5764227 and topotecan in adults with relapsed small cell lung cancer

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:GSK5764227
  • Sponsor:Glaxosmithkline Research & Development Limited

Study of alteplase and tenecteplase for intravenous thrombolysis in patients with ischemic stroke who are taking direct oral anticoagulants

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Alteplase
  • Sponsor:Insel Gruppe AG

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Clinical research in Coimbra

What the registry says about research in the country

01 Ophthalmology & Vision

Innovative trials investigating treatments for polypoidal choroidal vasculopathy and thyroid eye disease, focusing on improving visual outcomes and reducing eye-related complications.

  • Retinal conditions
  • Orbital disorders
  • Visual acuity improvement

Advanced therapeutic approaches using intravitreal injections and targeted medications.

02 Dermatology

Groundbreaking research addressing various skin conditions including hidradenitis suppurativa, pyoderma gangrenosum, and neurodermatitis.

  • Inflammatory skin diseases
  • Chronic skin conditions
  • Autoimmune dermatological disorders

Novel therapeutic approaches targeting specific inflammatory pathways.

03 Cardiovascular Medicine

Comprehensive studies exploring treatments for cardiovascular disease and pulmonary arterial hypertension, with focus on preventing major adverse cardiac events.

  • Heart disease prevention
  • Vascular conditions
  • Lipid management

Innovative therapies targeting specific cardiovascular risk factors.

04 Neurology

Advanced research in ischemic stroke, epilepsy, and migraine treatments, exploring both acute interventions and preventive therapies.

  • Stroke management
  • Seizure disorders
  • Headache conditions

Cutting-edge therapeutic approaches for neurological disorders.

05 Oncology

Studies focusing on breast cancer, non-small cell lung cancer, and leiomyosarcoma, developing targeted therapies for various cancer types.

  • Metastatic disease
  • Combination therapies
  • Targeted treatments

Innovative approaches in cancer treatment and management.

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