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Clinical trials in Coimbra – page 5

263 clinical trials in Coimbra, Portugal across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Coimbra at a glance
263
clinical trials
  • Research sites2
Type of trial
Recruitment status
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263 trials in Coimbra

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Dry age-related macular degeneration

Recruiting

Study of ONL1204 eye injections to slow vision loss in patients with age-related macular degeneration and geographic atrophy

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Xelafaslatide
  • Sponsor:ONL Therapeutics Inc.

Relapsing multiple sclerosis

Recruiting

Study comparing remibrutinib and ocrelizumab in patients with relapsing multiple sclerosis who switch from ocrelizumab treatment

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Ocrelizumab
  • Sponsor:Novartis Pharma AG

Colitis ulcerative+1

Recruiting

Long-term safety study of subcutaneous vedolizumab in children and adolescents with ulcerative colitis or Crohn's disease

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:0–17 years
  • Substances:Vedolizumab
  • Sponsor:Takeda Development Center Americas Inc.

Plasma cell myeloma

Recruiting

Study comparing daratumumab, lenalidomide and dexamethasone followed by linvoseltamab versus continued initial treatment in newly diagnosed multiple myeloma patients

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Daratumumab
  • Sponsor:Emn Trial Office S.r.l. Impresa Sociale

Squamous cell carcinoma of head and neck

Recruiting

Study of ficerafusp alfa and pembrolizumab as first treatment for patients with PD-L1-positive recurrent or metastatic head and neck cancer

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:Bicara Therapeutics Inc.

IgA nephropathy

Recruiting

Study of felzartamab compared to placebo in adults with IgA nephropathy

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Codeine Phosphate
  • Sponsor:Biogen Idec Research Limited

Hypochondroplasia

Recruiting

Study on the Effectiveness and Safety of Infigratinib for Children with Hypochondroplasia and Short Stature

Registered drug
Countries:PortugalPortugal
  • Participants:0–17 years
  • Substances:Infigratinib
  • Sponsor:Qed Therapeutics Inc.

Primary biliary cholangitis

Recruiting

Study of Seladelpar Treatment in Patients with Primary Biliary Cholangitis and Compensated Cirrhosis

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Seladelpar
  • Sponsor:Gilead Sciences Inc.

Polypoidal choroidal vasculopathy

Recruiting

Study on the Effects of Faricimab for Caucasian Patients with Polypoidal Choroidal Vasculopathy

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Faricimab
  • Sponsor:Association For Innovation And Biomedical Research On Light And Image

Epileptic encephalopathy

Recruiting

Study on the Safety and Effectiveness of Bexicaserin for Seizures in Children and Adults with Developmental and Epileptic Encephalopathy

Investigational
Countries:PortugalPortugal
  • Participants:0–17 years · 18–64 years · 65+ years
  • Sponsor:Longboard Pharmaceuticals Inc.

Study of Rilvegostomig or Pembrolizumab for First-line Treatment in Patients with PD-L1-high Metastatic Non-small Cell Lung Cancer

Recruiting
Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Infliximab
  • Sponsor:AstraZeneca AB

Non-small cell lung cancer+2

Recruiting

Study Comparing Nivolumab and Relatlimab with Chemotherapy to Pembrolizumab with Chemotherapy for Advanced Non-Small Cell Lung Cancer Patients

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Clinical research in Coimbra

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01 Ophthalmology & Vision

Innovative trials investigating treatments for polypoidal choroidal vasculopathy and thyroid eye disease, focusing on improving visual outcomes and reducing eye-related complications.

  • Retinal conditions
  • Orbital disorders
  • Visual acuity improvement

Advanced therapeutic approaches using intravitreal injections and targeted medications.

02 Dermatology

Groundbreaking research addressing various skin conditions including hidradenitis suppurativa, pyoderma gangrenosum, and neurodermatitis.

  • Inflammatory skin diseases
  • Chronic skin conditions
  • Autoimmune dermatological disorders

Novel therapeutic approaches targeting specific inflammatory pathways.

03 Cardiovascular Medicine

Comprehensive studies exploring treatments for cardiovascular disease and pulmonary arterial hypertension, with focus on preventing major adverse cardiac events.

  • Heart disease prevention
  • Vascular conditions
  • Lipid management

Innovative therapies targeting specific cardiovascular risk factors.

04 Neurology

Advanced research in ischemic stroke, epilepsy, and migraine treatments, exploring both acute interventions and preventive therapies.

  • Stroke management
  • Seizure disorders
  • Headache conditions

Cutting-edge therapeutic approaches for neurological disorders.

05 Oncology

Studies focusing on breast cancer, non-small cell lung cancer, and leiomyosarcoma, developing targeted therapies for various cancer types.

  • Metastatic disease
  • Combination therapies
  • Targeted treatments

Innovative approaches in cancer treatment and management.

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