Clinical trials in Heerlen – page 2

97 clinical trials in Heerlen, The Netherlands. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Heerlen at a glance

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97 trials in Heerlen

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Triple negative breast cancer

Recruiting

Evaluating sacituzumab tirumotecan alone or with pembrolizumab compared to standard treatment in untreated patients with metastatic triple-negative breast cancer with low PD-L1 expression

Registered drugNo placebo

Evaluating sacituzumab tirumotecan alone or with pembrolizumab compared to standard treatment in untreated patients with metastatic triple-negative breast cancer with low PD-L1 expression

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Merck Sharp & Dohme LLC

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Non-small cell lung cancer+2

Recruiting

Study Comparing Nivolumab and Relatlimab with Chemotherapy to Pembrolizumab with Chemotherapy for Advanced Non-Small Cell Lung Cancer Patients

Registered drugNo placebo

Study Comparing Nivolumab and Relatlimab with Chemotherapy to Pembrolizumab with Chemotherapy for Advanced Non-Small Cell Lung Cancer Patients

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Small cell lung cancer extensive stage

Recruiting

Study Comparing Sacituzumab Govitecan and Standard Treatment for Patients with Previously Treated Extensive Stage Small Cell Lung Cancer

Registered drugNo placebo

Study Comparing Sacituzumab Govitecan and Standard Treatment for Patients with Previously Treated Extensive Stage Small Cell Lung Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Topotecan
Sponsor:Gilead Sciences Inc.

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Cardiac failure+1

Recruiting

Study on CDR132L for Heart Failure with Reduced Ejection Fraction and Left Ventricular Hypertrophy in Adults

Investigational

Study on CDR132L for Heart Failure with Reduced Ejection Fraction and Left Ventricular Hypertrophy in Adults

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Novo Nordisk A/S

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Cerebral haemorrhage

Recruiting

Study of clopidogrel and acetylsalicylic acid (aspirin) for prevention of cardiovascular events in patients who survived intracerebral hemorrhage stroke

Registered drugNo placebo

Study of clopidogrel and acetylsalicylic acid (aspirin) for prevention of cardiovascular events in patients who survived intracerebral hemorrhage stroke

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Acetylsalicylic Acid
Sponsor:University Of Edinburgh

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Appendicitis+4

Recruiting

Study on Using Gentamicin and Clindamycin to Prevent Abscesses After Surgery for Complicated Appendicitis in Patients

Registered drugNo placebo

Study on Using Gentamicin and Clindamycin to Prevent Abscesses After Surgery for Complicated Appendicitis in Patients

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Clindamycin
Sponsor:Amsterdam UMC Stichting

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Malignant melanoma

Recruiting

Study on Stopping Nivolumab or Pembrolizumab in Advanced Melanoma Patients After Achieving a Response

Registered drugNo placebo

Study on Stopping Nivolumab or Pembrolizumab in Advanced Melanoma Patients After Achieving a Response

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Nivolumab
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Ischaemic stroke

Recruiting

Study on Statins for Frail Older Patients with Recent Ischemic Stroke or TIA: Fluvastatin, Simvastatin, Pravastatin Sodium, Atorvastatin, and Rosuvastatin Combination

Registered drugNo placebo

Study on Statins for Frail Older Patients with Recent Ischemic Stroke or TIA: Fluvastatin, Simvastatin, Pravastatin Sodium, Atorvastatin, and Rosuvastatin Combination

Registered drugNo placebo

The Netherlands

Participants:65+ years
Substances:Atorvastatin
Sponsor:Amsterdam UMC Stichting

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Peripheral artery restenosis+4

Recruiting

Study on the Effect of Clopidogrel and Acetylsalicylic Acid on Reducing Heart and Blood Vessel Events in Patients with Peripheral Arterial Disease

Registered drug

Study on the Effect of Clopidogrel and Acetylsalicylic Acid on Reducing Heart and Blood Vessel Events in Patients with Peripheral Arterial Disease

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Acetylsalicylic Acid
Sponsor:Universitair Medisch Centrum Utrecht

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Cerebrovascular accident

Recruiting

Study on Stopping or Continuing Clopidogrel, Carbasalate Calcium, and Dipyridamole for Young Patients After Stroke Without a Known Cause

Registered drugNo placebo

Study on Stopping or Continuing Clopidogrel, Carbasalate Calcium, and Dipyridamole for Young Patients After Stroke Without a Known Cause

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Acetylsalicylic Acid
Sponsor:Stichting Radboud universitair medisch centrum

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Obesity

Recruiting

Study of Semaglutide for Weight Loss in Obesity Patients with Low Response After Bariatric Surgery

InvestigationalNo placebo

Study of Semaglutide for Weight Loss in Obesity Patients with Low Response After Bariatric Surgery

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Semaglutide
Sponsor:Zuyderland Medisch Centrum Stichting

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Subdural haematoma

Recruiting

Study on Tranexamic Acid to Prevent Surgery in Patients with Chronic Subdural Hematoma

Registered drug

Study on Tranexamic Acid to Prevent Surgery in Patients with Chronic Subdural Hematoma

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Tranexamic Acid
Sponsor:Amsterdam UMC Stichting

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Clinical research in Heerlen

What the registry says about research in the country

01 Neurological Disorders

Research focusing on multiple sclerosis and stroke management, including trials evaluating new therapeutic approaches for both relapsing and progressive forms of MS.

MS Treatment Innovations
Stroke Prevention Studies
Cerebral Hemorrhage Management

Novel therapies being tested include frexalimab and tolebrutinib for multiple sclerosis patients.

02 Oncology Research

Comprehensive studies in cancer treatment, with particular focus on lung cancer, melanoma, and prostate cancer therapies.

Non-Small Cell Lung Cancer Treatments
Advanced Melanoma Management
Prostate Cancer Diagnostics

Innovative approaches including PSMA-PET/CT imaging and immunotherapy combinations are being evaluated.

03 Cardiovascular Medicine

Studies addressing cardiovascular diseases and related conditions, including innovative treatments for heart disease and stroke prevention.

Major Cardiovascular Events Prevention
Atrial Fibrillation Management
Lipid-Lowering Therapies

Trials include pelacarsen for cardiovascular risk reduction and statin therapy evaluations.

04 Respiratory Medicine

Research into pulmonary conditions, particularly focusing on fibrotic lung diseases and their treatment approaches.

Pulmonary Fibrosis Treatments
Interstitial Lung Disease Studies
Long-term Safety Evaluations

Including trials of inhaled treprostinil and nerandomilast for various forms of lung fibrosis.

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