Study on HPV Vaccine for Women with Vulvar HSIL: Evaluating the Effectiveness of Nonavalent HPV Vaccine in Preventing Recurrence of Vulvar High-Grade Lesions

Registered drug

Study on HPV Vaccine for Women with Vulvar HSIL: Evaluating the Effectiveness of Nonavalent HPV Vaccine in Preventing Recurrence of Vulvar High-Grade Lesions

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Human Papillomavirus Type 11 L1 Protein - Adsorbed - In The Form Of Virus-Like Particles Produced In Yeast Cells (Saccharomyces Cerevisiae Canade 3C-5 (Strain 1895)) By Rdna
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Hormone-refractory prostate cancer

Recruiting

Study Comparing MK-5684 with Abiraterone Acetate or Enzalutamide for Patients with Advanced Prostate Cancer After Hormonal Therapy and Chemotherapy

Registered drugNo placebo

Study Comparing MK-5684 with Abiraterone Acetate or Enzalutamide for Patients with Advanced Prostate Cancer After Hormonal Therapy and Chemotherapy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Abiraterone Acetate
Sponsor:Merck Sharp & Dohme LLC

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Study on the Effects of Baricitinib and Drug Combination for Adults with Severe Community-Acquired Pneumonia, Severe Influenza, or Severe and Moderate COVID-19

Recruiting

Registered drugNo placebo

Study on the Effects of Baricitinib and Drug Combination for Adults with Severe Community-Acquired Pneumonia, Severe Influenza, or Severe and Moderate COVID-19

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Amoxicillin Sodium
Sponsor:Universitair Medisch Centrum Utrecht

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Oesophageal carcinoma

Recruiting

Study on Preventing Infections After Esophageal Cancer Surgery Using Colistin Sulfate, Tobramycin, and Amphotericin B in Patients with Resectable Esophageal Cancer

Registered drugNo placebo

Study on Preventing Infections After Esophageal Cancer Surgery Using Colistin Sulfate, Tobramycin, and Amphotericin B in Patients with Resectable Esophageal Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Amphotericin B
Sponsor:Stichting Radboud universitair medisch centrum

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Prolymphocytic leukaemia+2

Recruiting

Study on the Effectiveness of Entrectinib and Other Drug Combinations for Patients with Advanced Solid Tumors, Multiple Myeloma, or Non-Hodgkin Lymphoma

Registered drugNo placebo

Study on the Effectiveness of Entrectinib and Other Drug Combinations for Patients with Advanced Solid Tumors, Multiple Myeloma, or Non-Hodgkin Lymphoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Abemaciclib
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Relapsing multiple sclerosis+2

Recruiting

Study on Long-Term Safety of Tolebrutinib and Teriflunomide for Patients with Multiple Sclerosis

Registered drug

Study on Long-Term Safety of Tolebrutinib and Teriflunomide for Patients with Multiple Sclerosis

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Teriflunomide
Sponsor:Sanofi-Aventis Recherche & Developpement

Contact Research Centre

Obesity+1

Recruiting

Study on Tranexamic Acid and Sodium Chloride to Reduce Bleeding in Gastric Bypass Surgery for Patients with Severe Obesity

Registered drug

Study on Tranexamic Acid and Sodium Chloride to Reduce Bleeding in Gastric Bypass Surgery for Patients with Severe Obesity

Registered drug

The Netherlands

Participants:18–64 years
Substances:Sodium Chloride
Sponsor:Sint Franciscus Vlietland Groep Stichting

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Interstitial lung disease

Recruiting

Study on Long-Term Safety of Inhaled Treprostinil for Patients with Fibrotic Lung Disease

InvestigationalNo placebo

Study on Long-Term Safety of Inhaled Treprostinil for Patients with Fibrotic Lung Disease

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Treprostinil
Sponsor:United Therapeutics Corp.

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Dermatomyositis+2

Recruiting

Study on Filgotinib for Patients with Refractory Behcet's Disease, Idiopathic Inflammatory Myopathies, and IgG4-Related Disease

Registered drugNo placebo

Study on Filgotinib for Patients with Refractory Behcet's Disease, Idiopathic Inflammatory Myopathies, and IgG4-Related Disease

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Filgotinib
Sponsor:Universitair Medisch Centrum Utrecht

Contact Research Centre

Electrocardiogram ST segment elevation

Recruiting

Study on Rituximab for Patients with Acute Myocardial Infarction

Registered drug

Study on Rituximab for Patients with Acute Myocardial Infarction

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Rituximab
Sponsor:Assistance Publique Hopitaux De Paris

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Other cities in the Netherlands

The busiest research cities in the country

All 103 cities in the Netherlands

Clinical research in Heerlen

What the registry says about research in the country

01 Neurological Disorders

Research focusing on multiple sclerosis and stroke management, including trials evaluating new therapeutic approaches for both relapsing and progressive forms of MS.

MS Treatment Innovations
Stroke Prevention Studies
Cerebral Hemorrhage Management

Novel therapies being tested include frexalimab and tolebrutinib for multiple sclerosis patients.

02 Oncology Research

Comprehensive studies in cancer treatment, with particular focus on lung cancer, melanoma, and prostate cancer therapies.

Non-Small Cell Lung Cancer Treatments
Advanced Melanoma Management
Prostate Cancer Diagnostics

Innovative approaches including PSMA-PET/CT imaging and immunotherapy combinations are being evaluated.

03 Cardiovascular Medicine

Studies addressing cardiovascular diseases and related conditions, including innovative treatments for heart disease and stroke prevention.

Major Cardiovascular Events Prevention
Atrial Fibrillation Management
Lipid-Lowering Therapies

Trials include pelacarsen for cardiovascular risk reduction and statin therapy evaluations.

04 Respiratory Medicine

Research into pulmonary conditions, particularly focusing on fibrotic lung diseases and their treatment approaches.

Pulmonary Fibrosis Treatments
Interstitial Lung Disease Studies
Long-term Safety Evaluations

Including trials of inhaled treprostinil and nerandomilast for various forms of lung fibrosis.

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Clinical trials in Heerlen – page 3

97 trials in Heerlen

Oesophageal adenocarcinoma

Study on Adding Trastuzumab and Pertuzumab to Treatment for Patients with Resectable HER2 Positive Esophageal Cancer

Pulmonary sarcoidosis

Study on Methotrexate and Prednisone for Treating Lung Sarcoidosis in Patients

Human papilloma virus immunisation+1

Study on HPV Vaccine for Women with Vulvar HSIL: Evaluating the Effectiveness of Nonavalent HPV Vaccine in Preventing Recurrence of Vulvar High-Grade Lesions

Hormone-refractory prostate cancer

Study Comparing MK-5684 with Abiraterone Acetate or Enzalutamide for Patients with Advanced Prostate Cancer After Hormonal Therapy and Chemotherapy

Study on the Effects of Baricitinib and Drug Combination for Adults with Severe Community-Acquired Pneumonia, Severe Influenza, or Severe and Moderate COVID-19

Study on the Effects of Baricitinib and Drug Combination for Adults with Severe Community-Acquired Pneumonia, Severe Influenza, or Severe and Moderate COVID-19

Oesophageal carcinoma

Study on Preventing Infections After Esophageal Cancer Surgery Using Colistin Sulfate, Tobramycin, and Amphotericin B in Patients with Resectable Esophageal Cancer

Prolymphocytic leukaemia+2

Study on the Effectiveness of Entrectinib and Other Drug Combinations for Patients with Advanced Solid Tumors, Multiple Myeloma, or Non-Hodgkin Lymphoma

Relapsing multiple sclerosis+2

Study on Long-Term Safety of Tolebrutinib and Teriflunomide for Patients with Multiple Sclerosis

Obesity+1

Study on Tranexamic Acid and Sodium Chloride to Reduce Bleeding in Gastric Bypass Surgery for Patients with Severe Obesity

Interstitial lung disease

Study on Long-Term Safety of Inhaled Treprostinil for Patients with Fibrotic Lung Disease

Dermatomyositis+2

Study on Filgotinib for Patients with Refractory Behcet's Disease, Idiopathic Inflammatory Myopathies, and IgG4-Related Disease

Electrocardiogram ST segment elevation

Study on Rituximab for Patients with Acute Myocardial Infarction

Filter the trials

Other cities in the Netherlands

Clinical research in Heerlen

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