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Musculoskeletal and connective tissue disorders – page 36

  • 872 clinical trials
  • 359 recruiting
  • 331 conditions
  • 28 countries

Conditions in this area

331 conditions with trials, the busiest first

Rheumatoid arthritis75Osteoarthritis63Systemic lupus erythematosus63Psoriatic arthropathy46Myasthenia gravis44Systemic scleroderma40Sjogren's syndrome31Duchenne muscular dystrophy28Soft tissue sarcoma28Axial spondyloarthritis21Juvenile idiopathic arthritis21Back pain19Ewing's sarcoma19Lupus nephritis18Spinal muscular atrophy17Dermatomyositis16Cutaneous lupus erythematosus14Glycogen storage disease type II14Myotonic dystrophy12Osteochondrodysplasia12Osteosarcoma12Rhabdomyosarcoma11Sarcoma11Osteoporosis10+307

Clinical trials in Musculoskeletal and connective tissue disorders

872 trials across Europe, recruiting first

Type of trial
Recruitment status
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872 clinical trials

Polymyalgia rheumatica

Not yet recruiting

A study to evaluate the safety and effectiveness of resomelagon in patients with polymyalgia rheumatica who are in remission using glucocorticoids

Investigational
Countries:DenmarkDenmark
  • Participants:18–64 years · 65+ years
  • Substances:Resomelagon
  • Sponsor:Synact Pharma ApS

Axial spondyloarthritis+1

Not yet recruiting

Study to evaluate the effect of upadacitinib on the frequency of eye inflammation in patients with axial spondyloarthritis.

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Upadacitinib
  • Sponsor:Care Arthritis Ltd.

Sjogren's syndrome

Not yet recruiting

A study to evaluate the effect of obinutuzumab on removing specific immune cells in the tissues of patients with Sjögren's syndrome.

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:18–64 years · 65+ years
  • Substances:Obinutuzumab
  • Sponsor:Stichting Radboud universitair medisch centrum

Osteoporosis postmenopausal

Not yet recruiting

Comparing the effect of romosozumab and denosumab on coronary artery damage in women with postmenopausal osteoporosis

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Denosumab
  • Sponsor:Ospedale Galeazzi S.p.A.

Bone sarcoma

Not yet recruiting

Study of regorafenib as maintenance treatment after first-line therapy in patients with bone sarcomas without remaining disease

Investigational
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Regorafenib
  • Sponsor:Centre Leon Berard

Systemic scleroderma

Not yet recruiting

Comparing Dapagliflozin and Tocilizumab for Treating Patients with Systemic Sclerosis

Registered drug
Countries:PolandPoland
  • Participants:18–64 years · 65+ years
  • Substances:Dapagliflozin
  • Sponsor:Centrum Medycznego Ksztalcenia Podyplomowego

Psoriatic arthropathy

Not yet recruiting

A Study of Guselkumab and Ciclosporin in Patients with Early Psoriatic Arthritis Transitioning from Skin to Joint Disease

Registered drugNo placebo
Countries:ItalyItaly
  • Participants:18–64 years · 65+ years
  • Substances:Ciclosporin
  • Sponsor:Azienda Sanitaria Universitaria Friuli Centrale

Fibromyalgia

Not yet recruiting

Study of rituximab for reducing pain in patients with fibromyalgia caused by autoantibodies

Registered drugNo placebo
Countries:SwedenSweden
  • Participants:18–64 years
  • Substances:Methylprednisolone
  • Sponsor:Region Stockholm – SLSO

Congenital myopathy

Not yet recruiting

Study of ASP2957 Gene Therapy for Male Patients with X-linked Myotubular Myopathy Who Require Breathing Support with Ventilators

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:ASP2957
  • Sponsor:Astellas Gene Therapies Inc.

Osteoarthritis

Not yet recruiting

Comparing nerve block methods with ropivacaine and epinephrine for pain relief in patients undergoing total knee replacement surgery for knee osteoarthritis

Registered drugNo placebo
Countries:SpainSpain
  • Participants:18–64 years · 65+ years
  • Substances:Epinephrine
  • Sponsor:Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques August Pi I Sunyer

Systemic lupus erythematosus+1

Not yet recruiting

A Study of Obecabtagene Autoleucel for Patients with Severe Lupus and Active Kidney Inflammation Not Responding to Standard Treatment

Registered drugNo placebo
Countries:GreeceGreece
  • Participants:18–64 years
  • Substances:Cyclophosphamide
  • Sponsor:Autolus Limited

Back pain

Not yet recruiting

Study of Ropivacaine and Dexamethasone Nerve Block for Patients with Acute Low Back Pain

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Ketoprofen
  • Sponsor:Centre Hospitalier Universitaire De Montpellier

Substances studied in this area

The therapies tested most often in Musculoskeletal and connective tissue disorders trials.

Sodium Chloride47 clinical trialsParacetamol32 clinical trialsTocilizumab29 clinical trialsMethotrexate26 clinical trialsAdalimumab24 clinical trialsRituximab23 clinical trialsCyclophosphamide20 clinical trialsEtanercept20 clinical trialsBaricitinib17 clinical trials
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