Rare diseases
Investigational molecules
Locations
Study of melpida with drug combination in patients with Hereditary Spastic Paraplegia Type 50 (SPG50)
SpainEfficacy and Safety of Transmucosal Midazolam for Proportional Palliative Sedation in Children with Refractory Symptoms
FrancePreventing urinary tract infections in infants and children under 2 years with oral Escherichia coli strain Nissle 1917 probiotic: a randomized controlled trial
FinlandStudy of blinatumomab plus drug combination in children and adolescents with acute lymphoblastic leukemia
GermanyIntranasal remestemcel therapy for newborns with hypoxic‑ischemic brain injury: a phase II placebo‑controlled trial
The NetherlandsBrain Fluid Clearance Guided Intrathecal Chemotherapy with Gadobutrol in Adolescents aged 12-17 with Acute Lymphoblastic Leukemia and Lymphoma
NorwaySafety and Tolerability of Intrathecal ION337 in Patients with Dravet Syndrome
BelgiumMaintenance versus tapered TNF‑alpha inhibitor therapy (golimumab, etanercept, adalimumab) in children and adolescents with juvenile idiopathic arthritis
NorwayPharmacokinetics, Safety, and Immunogenicity of Subcutaneous Ocrelizumab in Children and Adolescents with Relapsing‑Remitting Multiple Sclerosis
FranceIntranasal Dexmedetomidine for Pain Relief During Retinopathy of Prematurity Screening in Preterm Infants <30 Weeks Gestation Using Standard Drug Combination
NorwayShort Course Amoxicillin for Children with Acute Streptococcal Pharyngotonsillitis: A Phase III Randomized Trial
SpainSafety and pharmacodynamics of cangrelor tetrasodium in paediatric patients with congenital heart disease undergoing percutaneous vascular procedures
AustriaClinical research plays a vital role in developing safe and effective treatments for younger patients. Pediatric clinical trials are trials designed specifically for infants, children, and adolescents. They help researchers understand how new therapies, vaccines, or medical procedures work in younger populations and ensure that treatments are safe and appropriate for their age group.
Children are not simply smaller versions of adults. Their bodies grow and develop, which means medications may work differently than they do in adults. For this reason, therapies must be carefully studied in pediatric populations.
Another important reason for pediatric clinical trials is that some diseases occur primarily or exclusively in children. Certain genetic conditions, developmental disorders, and rare pediatric diseases affect only young patients. Without dedicated research involving children and adolescents, it would be difficult to develop treatments specifically designed for these conditions.
Pediatric research also helps doctors determine:
Participants in pediatric clinical trials may include infants, children, and teenagers depending on the trial design. Each trial has specific eligibility criteria based on age, health condition, and medical history.
Because participants are minors, the process always involves:
This ensures that families fully understand the purpose of the research, the procedures involved, and any potential risks or benefits.
Safety is the highest priority in pediatric clinical trials. These trials follow strict ethical and regulatory standards in Europe and internationally. Research protocols are reviewed by ethics committees and regulatory authorities to ensure that the risks are minimized and justified by the potential benefits of the research.
Children participating in clinical trials are monitored closely by qualified healthcare professionals throughout the entire process. Families receive detailed information about trial procedures, medical monitoring, and the right to withdraw from the trial at any time.
Our search platform allows parents and guardians to explore pediatric clinical trials available in different regions. Using the search tool, families can find trials based on factors such as age group, medical condition, and location.
Clinical trials for children and adolescents are essential for advancing pediatric medicine. By participating in research, families contribute to the development of safer and more effective treatments for young patients today and in the future.
Tell us about your condition – we search every trial in Europe and connect you with the right site.
