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Clinical Trials – home

Find clinical trials for children in your area – page 55

recruiting
314
countries
27
conditions
393

759 paediatric trials match your criteria

Long-Term Study of Tofacitinib for Children and Teens with Juvenile Idiopathic Arthritis

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Tofacitinib

Colitis ulcerative

Not recruiting

Study on Vedolizumab for Children with Moderate to Severe Ulcerative Colitis

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Prednisone

Study of Entrectinib in Children and Adolescents with Advanced or Metastatic Solid Tumors or Primary CNS Tumors with No Satisfactory Treatment Options

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Entrectinib

Study on the Effectiveness and Safety of Oral Semaglutide Compared to Placebo in Children and Adolescents with Type 2 Diabetes Using Metformin or Basal Insulin

Registered drug
Countries:AustriaAustria
  • Participants:0–17 years
  • Substances:Semaglutide

Study on the Safety and Feasibility of Diamyd (Glutamate Decarboxylase 2) for Individuals Aged 8-17 at Risk for Type 1 Diabetes with HLA DR3-DQ2 Haplotype

InvestigationalNo placebo
Countries:SwedenSweden
  • Participants:0–17 years
  • Substances:Glutamate decarboxylase 2, human, recombinant

Study on Belimumab for Children with Systemic Lupus Erythematosus (SLE)

Registered drug
Countries:SpainSpain
  • Participants:0–17 years
  • Substances:Belimumab

Study on Oral Glibenclamide for Managing High Blood Sugar in Premature Infants Weighing Less Than 1500g

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Glibenclamide

Colitis ulcerative

Not recruiting

Study of Tofacitinib for Children with Moderate to Severe Ulcerative Colitis

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Tofacitinib
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Avelumab

Renal transplant

Not recruiting

Personalized Tacrolimus Treatment for Children with Kidney Transplants Using a Dosing Algorithm

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years
  • Substances:Tacrolimus

Study Comparing Tacrolimus Levels in Children with Organ Transplants Switching from Prograf to Advagraf

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:0–17 years
  • Substances:Tacrolimus

Study on Mepolizumab for Children and Teens with Hypereosinophilic Syndrome

Registered drugNo placebo
Countries:The NetherlandsThe Netherlands
  • Participants:0–17 years
  • Substances:Mepolizumab

About paediatric clinical trials

Pediatric Clinical Trials: Research Opportunities for Children and Adolescents

Clinical research plays a vital role in developing safe and effective treatments for younger patients. Pediatric clinical trials are trials designed specifically for infants, children, and adolescents. They help researchers understand how new therapies, vaccines, or medical procedures work in younger populations and ensure that treatments are safe and appropriate for their age group.

Why Pediatric Clinical Trials Are Important

Children are not simply smaller versions of adults. Their bodies grow and develop, which means medications may work differently than they do in adults. For this reason, therapies must be carefully studied in pediatric populations.

Another important reason for pediatric clinical trials is that some diseases occur primarily or exclusively in children. Certain genetic conditions, developmental disorders, and rare pediatric diseases affect only young patients. Without dedicated research involving children and adolescents, it would be difficult to develop treatments specifically designed for these conditions.

Pediatric research also helps doctors determine:

  • the correct dosage of medications for children of different ages
  • how developing organs respond to treatments
  • whether therapies are safe and effective in younger patients
  • how treatments affect long-term growth and development

Who Can Participate in Pediatric Clinical Trials

Participants in pediatric clinical trials may include infants, children, and teenagers depending on the trial design. Each trial has specific eligibility criteria based on age, health condition, and medical history.

Because participants are minors, the process always involves:

  • Informed consent from parents or legal guardians
  • Age-appropriate explanation of the trial to the child
  • In many cases, assent from the child or adolescent confirming they agree to participate

This ensures that families fully understand the purpose of the research, the procedures involved, and any potential risks or benefits.

Safety and Ethical Oversight

Safety is the highest priority in pediatric clinical trials. These trials follow strict ethical and regulatory standards in Europe and internationally. Research protocols are reviewed by ethics committees and regulatory authorities to ensure that the risks are minimized and justified by the potential benefits of the research.

Children participating in clinical trials are monitored closely by qualified healthcare professionals throughout the entire process. Families receive detailed information about trial procedures, medical monitoring, and the right to withdraw from the trial at any time.

How Families Can Find Pediatric Clinical Trials

Our search platform allows parents and guardians to explore pediatric clinical trials available in different regions. Using the search tool, families can find trials based on factors such as age group, medical condition, and location.

Clinical trials for children and adolescents are essential for advancing pediatric medicine. By participating in research, families contribute to the development of safer and more effective treatments for young patients today and in the future.

Clinical Trials Concierge

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