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Clinical trials in Kladno

18 clinical trials in Kladno, Czechia. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Kladno at a glance
18
clinical trials
  • Paediatric trials0
  • Research sites0
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18 trials in Kladno

Open in trial search
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Golimumab
  • Sponsor:Janssen Cilag International

Agitation+1

Recruiting

A study to evaluate the safety and effectiveness of dextromethorphan, deramciclane fumarate, and deramciclane in treating agitation in people with Alzheimer's disease

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Dextromethorphan Hydrobromide

Efficacy, Safety, and Tolerability of NBI-1065890 in Adults with Tardive Dyskinesia

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Sponsor:Neurocrine Biosciences Inc.

Efficacy and Safety of JNJ-78934804 (guselkumab and golimumab) in Adults with Moderately to Severely Active Ulcerative Colitis

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Golimumab
  • Sponsor:Janssen Cilag International

Crohn's disease

Recruiting

Study of icotrokinra for adults with moderately to severely active Crohn's disease

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

Testing icotrokinra compared to placebo for adults and adolescents with moderately to severely active ulcerative colitis

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Icotrokinra
  • Sponsor:Janssen Cilag International

Long-Term Safety Study of ACP-204 for Adults with Alzheimer's Disease Psychosis

InvestigationalNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:ACP-204 tartrate
  • Sponsor:Acadia Pharmaceuticals Inc.

Obesity+1

Not yet recruiting

A Phase III Study of Lenbelintide in Adults with Obesity or Overweight and Weight‑Related Comorbidity Without Type 2 Diabetes

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:AZD6234
  • Sponsor:AstraZeneca AB

Anxiety

Not yet recruiting

Efficacy of Etifoxine in Adults with Adjustment Disorder with Anxiety: A Randomized, Double‑Blind, Placebo‑Controlled Trial

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Etifoxine Hydrochloride
  • Sponsor:Biocodex

Migraine

Not recruiting

Study on the Safety and Effectiveness of MEDI0618 for Reducing Migraine Days in Adults with Episodic Migraine

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:MEDI0618
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Dyslipidaemia

Not recruiting

Study of Evolocumab to Prevent Heart Disease Events in High-Risk Patients Without Previous Heart Attack or Stroke

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Evolocumab
  • Sponsor:Amgen Inc.

Major depression

Not recruiting

Testing Ulotaront Added to Antidepressants for Adults with Major Depressive Disorder Who Did Not Respond Well to Initial Treatment

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Citalopram
  • Sponsor:Otsuka Pharmaceutical Development & Commercialization Inc.

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Clinical research in Kladno

What the registry says about research in the country

01 Mental Health Studies

Comprehensive research focusing on Major Depressive Disorder, investigating multiple therapeutic approaches including novel compounds for treatment-resistant cases.

  • Depression with anhedonia
  • Adjunctive therapy evaluation
  • Long-term safety assessments

Studies aim to improve treatment outcomes for patients with varying severity levels of depression.

02 Neurodegenerative Disorders

Innovative clinical trials targeting Alzheimer's Disease Psychosis, evaluating new therapeutic compounds for symptom management and long-term treatment.

  • Psychosis management
  • Safety evaluations
  • Extended treatment protocols

Research focuses on both acute symptom control and long-term disease management strategies.

03 Neurological Conditions

Advanced research into migraine prevention and treatment, including studies on both episodic and chronic forms of the condition.

  • Preventive therapies
  • Long-term effectiveness
  • Novel treatment approaches

Trials aim to develop more effective preventive treatments for various migraine presentations.

04 Gastrointestinal Research

Pioneering studies in Crohn's Disease treatment, examining innovative biological therapies for moderate to severe cases.

  • Clinical remission evaluation
  • Endoscopic response assessment
  • Subcutaneous treatments

Research focuses on developing more effective treatment options for inflammatory bowel conditions.

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